Elexacaftor/tezacaftor/ivacaftor, sold under the brand names Trikafta and Kaftrio, is a fixed-dose combination medication used to treat cystic fibrosis...

Elexacaftor is a medication that acts as cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It is available in a single pill with ivacaftor...

Symdeko. It was approved by the U.S. FDA in 2018. The combination of elexacaftor, tezacaftor, and ivacaftor is being sold as Trikafta. In 2019, the U...

combination medications, lumacaftor/ivacaftor, tezacaftor/ivacaftor, and elexacaftor/tezacaftor/ivacaftor which are used to treat people with cystic fibrosis...

treat people with the F508del mutation. In 2019, the combination drug elexacaftor/ivacaftor/tezacaftor, marketed as Trikafta,was approved for CF patients...

lumacaftor R07AX31 Ivacaftor and tezacaftor R07AX32 Ivacaftor, tezacaftor and elexacaftor "ATC (Anatomical Therapeutic Chemical Classification System) – Synopsis"...

filed with it, the FDA approved Vertex's Triple-combo therapy Trikafta (elexacaftor/tezacaftor/ivacaftor) for patients 12 and older with at least one F508del...

Pembrolizumab Merck endometrial carcinoma Lenvatinib Eisai endometrial carcinoma Elexacaftor/tezacaftor/ivacaftor Vertex Pharmaceuticals cystic fibrosis Zanubrutinib...

some approved CFTR modulators for specific mutations. One such drug is elexacaftor/tezacaftor/ivacaftor. However, the cost of CFTR modulators is high. In...

Most recently, Grootenhuis's team discovered Tezacaftor (VX-661) and Elexacaftor (VX-445), which in combination with Ivacaftor are the components of Trikafta...

the discovery of tezacaftor and elexacaftor, 2 other correctors of the CFTR protein. The triple combination elexacaftor/tezacaftor/ivacaftor was approved...