• Endopeptidase So (EC 3.4.21.67, E. coli cytoplasmic proteinase, proteinase So, Escherichia coli serine proteinase So) is an enzyme. This enzyme catalyses...
    1 KB (152 words) - 01:22, 22 June 2024
  • Thumbnail for Neprilysin
    Neprilysin (/ˌnɛprɪˈlaɪsɪn/; also known as membrane metallo-endopeptidase (MME), neutral endopeptidase (NEP), cluster of differentiation 10 (CD10) and common...
    23 KB (2,581 words) - 06:57, 21 July 2024
  • Thumbnail for Serine protease
    Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins. Serine serves as the nucleophilic amino acid at the (enzyme's)...
    22 KB (2,343 words) - 20:13, 29 August 2024
  • EC 3.4.21.64 Thermomycolin, EC 3.4.21.65 Thermitase, EC 3.4.21.66 Endopeptidase So, EC 3.4.21.67 This set index page lists enzyme articles associated...
    546 bytes (76 words) - 19:23, 11 March 2023
  • (oryzin), EC 3.4.21.64 (endopeptidase K), EC 3.4.21.65 (thermomycolin), EC 3.4.21.66 (thermitase) and EC 3.4.21.67 (endopeptidase So) EC 3.4.4.17: Now covered...
    119 KB (15,555 words) - 06:24, 19 September 2024
  • (formerly referred to as "dynorphin-converting enzyme"), an enzyme of the endopeptidase family. Leumorphin behaves as a potent and selective κ-opioid receptor...
    9 KB (519 words) - 02:53, 21 October 2021
  • Thumbnail for Cysteine protease
    Cysteine Peptidases Archived 2017-04-04 at the Wayback Machine Cysteine+endopeptidases at the U.S. National Library of Medicine Medical Subject Headings (MeSH)...
    14 KB (1,278 words) - 22:29, 25 April 2024
  • Thumbnail for Candoxatril
    prodrug of candoxatrilat (UK-73967). Human neutral endopeptidase (neprilysin) as the neutral endopeptidase 24.11 complexed (RB-101) with phosphoramidon degrades...
    9 KB (940 words) - 02:00, 5 June 2024
  • Thumbnail for 3C-like protease
    3C-like protease (3CLpro) or main protease (Mpro), formally known as C30 endopeptidase or 3-chymotrypsin-like protease, is the main protease found in coronaviruses...
    17 KB (1,653 words) - 12:43, 26 September 2024
  • Thumbnail for Chymosin
    or rennin /ˈrɛnɪn/ is a protease found in rennet. It is an aspartic endopeptidase belonging to MEROPS A1 family. It is produced by newborn ruminant animals...
    12 KB (1,306 words) - 17:48, 23 April 2024
  • oryzae strain RIB40 has 65 endopeptidase genes and 69 exopeptidase genes, and A. sojae strain SMF134 has 83 endopeptidase genes and 67 exopeptidase genes...
    17 KB (2,150 words) - 02:41, 15 October 2024
  • Thumbnail for Opiorphin
    (proline-rich, lacrimal 1). Opiorphin inhibits three proteases: neutral ecto-endopeptidase (MME), ecto-aminopeptidase N (ANPEP) and perhaps also a dipeptidyl peptidase...
    9 KB (757 words) - 05:28, 31 October 2023
  • Thumbnail for Progerin
    amino-acid group near the C-terminus of the prelamin A protein. The endopeptidase ZMPSTE24 cannot cleave between the missing RSY - LLG amino acid sequence...
    9 KB (1,036 words) - 15:42, 31 May 2024
  • Thumbnail for Factor XII
    factor XIIa (EC 3.4.21.38), an enzyme of the serine protease (or serine endopeptidase) class. In humans, factor XII is encoded by F12 gene. The gene for factor...
    25 KB (3,092 words) - 05:52, 25 September 2024
  • Thumbnail for S-17092
    enzyme prolyl endopeptidase. This enzyme is involved in the metabolic breakdown of a number of neuropeptide neurotransmitters in the brain, and so inhibiting...
    4 KB (322 words) - 01:20, 24 September 2024
  • Thumbnail for Lysin
    (lysozyme-like, EC 3.2.1.17) Endopeptidase N-acetylmuramoyl-L-alanine amidase (T7-like, EC 3.5.1.28) γ-D-glutaminyl-L-lysine endopeptidase (EC 3.4.14.13) Peptidoglycan...
    16 KB (1,989 words) - 07:05, 27 July 2024
  • Thumbnail for TEV protease
    TEV protease (EC 3.4.22.44, Tobacco Etch Virus nuclear-inclusion-a endopeptidase) is a highly sequence-specific cysteine protease from Tobacco Etch Virus...
    16 KB (1,866 words) - 02:28, 14 August 2024
  • Thumbnail for Factor X
    coagulation cascade, encoded in humans by F10 gene. It is a serine endopeptidase (protease group S1, PA clan). Factor X is synthesized in the liver and...
    27 KB (3,353 words) - 00:12, 28 October 2024
  • Thumbnail for Trypsin
    suggest cleavage occurs even with proline. Trypsin is considered an endopeptidase, i.e., the cleavage occurs within the polypeptide chain rather than...
    26 KB (2,827 words) - 03:08, 1 October 2024
  • Thumbnail for Cysteine
    ionized, and cysteine residues in proteins have pKa values close to neutrality, so are often in their reactive thiolate form in the cell. Because of its high...
    38 KB (3,795 words) - 15:00, 29 October 2024
  • Thumbnail for Plasmodium malariae
    published in 1997, Westling et al. focused their attention on the aspartic endopeptidase class of enzymes, simply called plasmepsins. They sought to characterize...
    24 KB (2,921 words) - 18:37, 12 August 2024
  • Thumbnail for Racecadotril
    pharmacodynamics, pharmacokinetics, and clinical effects of the neutral endopeptidase inhibitor racecadotril". Frontiers in Pharmacology. 3: 93. doi:10.3389/fphar...
    12 KB (920 words) - 20:04, 15 September 2024
  • Thumbnail for PYCARD
    in direct IL-1β processing regulation. Isoform 3 is an inhibitory isoform, so that it only co-localizes with caspase-1, but not with NLRs. Isoform 4 is...
    11 KB (1,338 words) - 13:44, 2 November 2024
  • modifications. Endopeptidases are enzymes that add water to an internal peptide bond in a peptide chain and break that bond. Three common endopeptidases that come...
    27 KB (2,828 words) - 23:11, 3 November 2024
  • Saccharopepsin (EC 3.4.23.25, yeast endopeptidase A, Saccharomyces aspartic proteinase, aspartic proteinase yscA, proteinase A, proteinase yscA, yeast...
    4 KB (462 words) - 15:46, 26 August 2023
  • Thumbnail for Tetanus toxin
    that membrane and into the neuron. The A-chain, an M27-family zinc endopeptidase, attacks the vesicle-associated membrane protein (VAMP). The TetX gene...
    17 KB (1,928 words) - 04:15, 5 November 2024
  • Thumbnail for Pepsin
    Pepsin /ˈpɛpsɪn/ is an endopeptidase that breaks down proteins into smaller peptides and amino acids. It is one of the main digestive enzymes in the digestive...
    30 KB (3,450 words) - 06:54, 10 June 2024
  • Thumbnail for Renin
    position. Renin activates the renin–angiotensin system by using its endopeptidase activity to cleave the peptide bonds between leucine and valine residues...
    18 KB (2,105 words) - 06:00, 5 November 2024
  • Thumbnail for Picornain 3C
    which cleaves peptide bonds of non-terminal sequences. Picornain 3C’s endopeptidase activity is primarily responsible for the catalytic process of selectively...
    19 KB (2,412 words) - 14:53, 29 September 2023
  • enkephalin opioid peptides. They include: Aminopeptidase N (APN) Neutral endopeptidase (NEP) Dipeptidyl peptidase 3 (DPP3) Carboxypeptidase A6 (CPA6) Leucyl/cystinyl...
    2 KB (159 words) - 16:44, 22 September 2024