• Exon shuffling is a molecular mechanism for the formation of new genes. It is a process through which two or more exons from different genes can be brought...
    18 KB (2,249 words) - 07:08, 22 February 2024
  • Thumbnail for Exon
    in overall reputable secondary sources. DBASS3/5 Exitron Exon-intron database Exon shuffling Interrupted gene Outron Twintron Untranslated region (UTR)...
    13 KB (1,517 words) - 23:39, 2 April 2024
  • Thumbnail for Genome evolution
    Exon shuffling is a mechanism by which new genes are created. This can occur when two or more exons from different genes are combined or when exons are...
    42 KB (4,943 words) - 09:10, 4 September 2024
  • Paralogous exon shuffling involves shuffling of exon from different genes from the same species. Paralogous domain shuffling involves shuffling of entire...
    58 KB (7,493 words) - 11:39, 18 July 2024
  • presence of these exons in protein transcripts. Exon shuffling Gene duplication Letunic I, Copley RR, Bork P (Jun 2002). "Common exon duplication in animals...
    1 KB (146 words) - 21:03, 8 April 2023
  • Thumbnail for Transposable element
    the adjacent base pairs; this phenomenon is called exon shuffling. Shuffling two unrelated exons can create a novel gene product or, more likely, an...
    60 KB (7,362 words) - 19:54, 10 May 2024
  • them, exon shuffling may occur. Exon shuffling is the creation of novel gene products due to the new placement of two previously unrelated exons through...
    26 KB (3,086 words) - 10:41, 3 December 2023
  • Thumbnail for Reverse transcriptase
    been shown to be involved in processes such as transcript fusions, exon shuffling and creating artificial antisense transcripts. It has been speculated...
    27 KB (3,043 words) - 03:16, 30 June 2024
  • spliceosome Outron Function MicroRNA Others: Exon shuffling Intein Noncoding DNA Noncoding RNA Selfish DNA Twintron Exon-intron database "The notion of the cistron...
    47 KB (5,839 words) - 23:00, 11 July 2024
  • Thumbnail for Perlecan
    that it has evolved from ancient ancestors by gene duplication and exon shuffling. Perlecan consists of a core protein of molecular weight 469 kDa to...
    84 KB (11,012 words) - 18:25, 12 September 2024
  • modifications. Comparative genomics DbDNV (2010) De novo gene birth Exon shuffling Gene amplification in Paramecium tetraurelia Gene fusion Horizontal...
    34 KB (3,679 words) - 17:16, 24 May 2024
  • for new genes through studies of homologues include gene duplication, exon shuffling, gene fusion and fission, etc. Studying the origins of a gene becomes...
    38 KB (4,621 words) - 03:27, 22 July 2024
  • genes result from domain shuffling, which is accomplished via exon shuffling, gene fusion, or gene fission. Domain shuffling has been found to be at least...
    17 KB (2,076 words) - 16:50, 9 June 2024
  • Thumbnail for Evolution
    to form new combinations with new functions (exon shuffling). When new genes are assembled from shuffling pre-existing parts, domains act as modules with...
    238 KB (24,717 words) - 15:06, 14 September 2024
  • Thumbnail for Major histocompatibility complex
    organizations of the MHC genes were a result of later cis-duplication and exon shuffling in a process termed "the MHC Big Bang." Genes in this locus are apparently...
    57 KB (6,753 words) - 06:14, 8 September 2024
  • Thumbnail for Lancelet
    animals sequenced to date, due to high rates of genetic changes like exon shuffling and domain combination. Among the three extant (living) genera, Asymmetron...
    63 KB (6,459 words) - 08:23, 16 September 2024
  • Thumbnail for Fusion gene
    fusion protein. Chimeric gene De novo gene birth ETV6-NTRK3 gene fusion Exon shuffling Gene duplication Horizontal gene transfer List of RNA-Seq bioinformatics...
    17 KB (1,928 words) - 19:40, 5 August 2024
  • do genes exhibit the supposed exon shuffling phenomenon. Furthermore, molecular biologists questioned the exon shuffling proposal, from a purely evolutionary...
    69 KB (8,037 words) - 13:18, 18 August 2024
  • Thumbnail for Mosaic protein
    Stemmer, Willem P. C. (2001-05-01). "Directed evolution of proteins by exon shuffling". Nature Biotechnology. 19 (5): 423–428. doi:10.1038/88084. PMID 11329010...
    5 KB (621 words) - 18:23, 2 June 2023
  • Thumbnail for Mobile genetic elements
    CLAssification of Mobile genetic Elements) database De novo gene birth Exon shuffling Gene fusion Gene duplication Horizontal gene transfer Virulence factors...
    33 KB (3,783 words) - 19:40, 6 April 2024
  • Q, et al. (December 2005). "Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains". Nat. Biotechnol. 23 (12): 1556–61...
    9 KB (732 words) - 21:50, 23 August 2023
  • Thumbnail for Circular RNA
    distinct alternatively spliced isoforms. Exon scrambling, also called exon shuffling, describes an event in which exons are spliced in a "non-canonical" (atypical)...
    55 KB (6,557 words) - 21:55, 24 August 2024
  • Thumbnail for CLEC11A
    secreted mucin-like protein with a C-type lectin domain: A new model of exon shuffling". Genomics. 57 (2): 316–7. doi:10.1006/geno.1999.5762. PMID 10198175...
    6 KB (753 words) - 02:50, 17 April 2022
  • Thumbnail for Short interspersed nuclear element
    retrotransposition. Insertion of a SINE upstream of a coding region may result in exon shuffling or changes to the regulatory region of the gene. Insertion of a SINE...
    41 KB (5,252 words) - 08:25, 18 July 2024
  • Evolutionary rate Excision repair Exconjugant Exogenote Exogenous DNA Exon Exon shuffling Exonuclease Expected progeny difference Experimental design Expressed...
    33 KB (2,517 words) - 18:31, 3 September 2024
  • Thumbnail for LCCL domain
    been used for the construction of various modular proteins through exon-shuffling. It has been found in various metazoan proteins in association with...
    4 KB (415 words) - 04:30, 1 January 2021
  • sequence would be captured. In this regard, Helitrons can be viewed as an exon shuffling machines. As a random sequence provides the novel termination signal...
    28 KB (3,784 words) - 18:50, 27 August 2023
  • ; Stemmer, W. P. C. (2005). "Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains". Nature Biotechnology. 23 (12):...
    4 KB (418 words) - 20:45, 28 March 2024
  • better understanding of its mechanism of action. combinatorial chemistry exon shuffling - note that although introns are conceptually analogous to inteins,...
    3 KB (422 words) - 10:11, 24 August 2023
  • sequence in RNA transcripts. Contrast exon. intron intrusion intron-mediated recombination See exon shuffling. invagination The infolding of a membrane...
    294 KB (27,232 words) - 03:46, 16 September 2024