• Thumbnail for FTO gene
    as alpha-ketoglutarate-dependent dioxygenase FTO is an enzyme that in humans is encoded by the FTO gene located on chromosome 16. As one homolog in the...
    35 KB (3,886 words) - 21:41, 7 June 2024
  • traded on the NYSE as FTO FTO, initialism used for the New South Wales Film and Television Office, former name of Screen NSW FTO gene, a fat mass and obesity-associated...
    551 bytes (107 words) - 22:10, 29 June 2022
  • 542–546. doi:10.2337/db11-1048. PMC 3266395. PMID 22210312. "Gene Symbol Report: FTO". HUGO Gene Nomenclature Committee. Archived from the original on 2012-10-24...
    36 KB (4,682 words) - 15:54, 2 April 2024
  • Thumbnail for Chocolate addiction
    between the FTO gene and intake of sugar and caffeine. The FTO gene works to regulate the body's energy usage. Some variants of the FTO gene play a major...
    36 KB (4,168 words) - 17:36, 27 August 2024
  • Thumbnail for Genetics of obesity
    Frayling TM, Timpson NJ, Weedon MN, et al. (2007). "A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult...
    25 KB (2,298 words) - 20:34, 9 March 2024
  • Thumbnail for Epigenetics
    plays a critical role in human energy homeostasis. The obesity-associated FTO gene is shown to be able to demethylate N6-methyladenosine in RNA. sRNAs are...
    161 KB (18,346 words) - 02:11, 20 August 2024
  • Thumbnail for Variant of uncertain significance
    controlling gene expression is the SNP found in an intron of the FTO gene. The FTO gene encodes the fat mass and obesity-associated protein, and the SNP...
    23 KB (2,275 words) - 11:29, 23 June 2024
  • Thumbnail for Obesity
    environment is present. People with two copies of the FTO gene (fat mass and obesity associated gene) have been found on average to weigh 3–4 kg more and...
    176 KB (18,794 words) - 07:01, 19 September 2024
  • will gain weight from a high fat diet; for people with AA genotype in the FTO gene showed a higher BMI compared those with TT genotype when having high fat...
    11 KB (1,347 words) - 00:53, 14 April 2024
  • Thumbnail for IRX3
    IRX3 (redirect from IRX3 (gene))
    decrease obesity markers in human cell cultures. Genetic variants of FTO and IRX3 genes are in high linkage disequilibrium and are associated with obesity...
    8 KB (937 words) - 03:11, 29 September 2024
  • Thumbnail for Tomas Lindahl
    F. M.; O'Rahilly, S.; Schofield, C. J. (2008). "The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science....
    16 KB (1,308 words) - 08:15, 18 September 2024
  • Thumbnail for N6-Methyladenosine
    mouse development, FTO has been shown to mediated LINE1 RNA m6A demethylation and consequently affect local chromatin state and nearby gene transcription....
    53 KB (5,629 words) - 21:25, 24 September 2024
  • Thumbnail for White people in the United Kingdom
    researchers described as the first clear genetic link, via the FTO gene, to obesity. Presence of the gene beyond that initial subject pool was not yet studied....
    78 KB (8,144 words) - 10:56, 3 September 2024
  • Thumbnail for Sadaf Farooqi
    mutations in the KSR2 gene are associated with insulin resistance and that genetic variation in the fat mass and obesity-associated protein (FTO) is associated...
    15 KB (1,303 words) - 08:12, 8 November 2023
  • Thumbnail for Childhood obesity
    ISBN 9780511544699. Frayling, Timothy M. (May 11, 2007). "A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult...
    84 KB (10,075 words) - 20:15, 29 September 2024
  • 1965), Italian criminal clan boss nicknamed "'o Chiatto" (Fatso) FTO gene, or Fatso, a gene linked to obesity and type 2 diabetes Fatso the Fat-Arsed Wombat...
    2 KB (241 words) - 01:39, 13 April 2023
  • (RBU). In 2010, work at the unit discovered that overexpression of the FTO gene led to obesity. The unit was in Oxfordshire. The unit carried out work...
    3 KB (180 words) - 13:48, 12 April 2024
  • Thumbnail for John Speakman
    examining polymorphic variation in the fat mass and obesity associated FTO gene. With Aberdeen colleague Ela Krol, among others, he has published a series...
    18 KB (2,074 words) - 12:49, 20 September 2024
  • Research Centre. Batterham identified that a genetic variation in the FTO gene can make people more likely to become obese. People with the obesity-risk...
    8 KB (844 words) - 00:23, 2 May 2024
  • for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene". PLOS Genet. 5 (8): e1000599. doi:10.1371/journal.pgen.1000599. ISSN 1553-7404...
    41 KB (4,203 words) - 06:12, 13 May 2024
  • Thumbnail for Enhancer (genetics)
    Gómez-Marín C, et al. (March 2014). "Obesity-associated variants within FTO form long-range functional connections with IRX3". Nature. 507 (7492): 371–375...
    52 KB (5,984 words) - 07:04, 5 August 2024
  • Thumbnail for NPC1
    NPC1 (redirect from NPC1 (gene))
    or responsible for obesity. These include genes such as MC4R, LEP, LEPR, and FTO. One of the lesser known gene diseases that is known to be linked to obesity...
    24 KB (2,718 words) - 10:56, 11 April 2024
  • Thumbnail for Chris Ponting
    F. M.; O'Rahilly, S.; Schofield, C. J. (2007). "The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science....
    23 KB (1,832 words) - 11:23, 4 February 2024
  • Thomas; Brüning, Jens C.; Rüther, Ulrich (2009). "Inactivation of the Fto gene protects from obesity". Nature. 458 (7240): 894–898. Bibcode:2009Natur...
    4 KB (319 words) - 10:12, 14 October 2023
  • of eating styles (notably satiety sensitivity) and established that the FTO gene contributes to obesity in part through effects on eating behaviour styles...
    16 KB (1,595 words) - 16:17, 30 September 2024
  • Thumbnail for Patrik Rorsman
    F. M.; O'Rahilly, S.; Schofield, C. J. (2007). "The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science....
    12 KB (955 words) - 08:26, 18 September 2024
  • Lindgren, C. M.; Perry, J. R. B.; et al. (2007). "A Common Variant in the FTO Gene is Associated with Body Mass Index and Predisposes to Childhood and Adult...
    19 KB (876 words) - 13:25, 13 January 2024
  • Thumbnail for Stephen O'Rahilly
    F. M.; O'Rahilly, S.; Schofield, C. J. (2007). "The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science....
    20 KB (1,630 words) - 00:10, 19 August 2024
  • RPGRIP1L (category Human chromosome 16 gene stubs)
    the RPGRIP1L gene, rs3213758, is associated with increased BMI. Genetic variations strongly associated with obesity within the FTO gene have also been...
    9 KB (952 words) - 03:31, 10 May 2024
  • Thumbnail for Manolis Kellis
    Christine; Glunk, Viktoria; Sousa, Isabel S.; Kellis, Manolis (2015-09-03). "FTO Obesity Variant Circuitry and Adipocyte Browning in Humans". New England...
    28 KB (2,678 words) - 15:23, 11 April 2024