as alpha-ketoglutarate-dependent dioxygenase FTO is an enzyme that in humans is encoded by the FTO gene located on chromosome 16. As one homolog in the...
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traded on the NYSE as FTO FTO, initialism used for the New South Wales Film and Television Office, former name of Screen NSW FTO gene, a fat mass and obesity-associated...
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Epigenetics of diabetes type 2 (section FTO loci)
542–546. doi:10.2337/db11-1048. PMC 3266395. PMID 22210312. "Gene Symbol Report: FTO". HUGO Gene Nomenclature Committee. Archived from the original on 2012-10-24...
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between the FTO gene and intake of sugar and caffeine. The FTO gene works to regulate the body's energy usage. Some variants of the FTO gene play a major...
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Genetics of obesity (section Genes)
Frayling TM, Timpson NJ, Weedon MN, et al. (2007). "A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult...
25 KB (2,298 words) - 20:34, 9 March 2024
Epigenetics (redirect from Epigenetic gene regulation)
plays a critical role in human energy homeostasis. The obesity-associated FTO gene is shown to be able to demethylate N6-methyladenosine in RNA. sRNAs are...
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Variant of uncertain significance (redirect from Gene of uncertain significance)
controlling gene expression is the SNP found in an intron of the FTO gene. The FTO gene encodes the fat mass and obesity-associated protein, and the SNP...
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environment is present. People with two copies of the FTO gene (fat mass and obesity associated gene) have been found on average to weigh 3–4 kg more and...
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will gain weight from a high fat diet; for people with AA genotype in the FTO gene showed a higher BMI compared those with TT genotype when having high fat...
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IRX3 (redirect from IRX3 (gene))
decrease obesity markers in human cell cultures. Genetic variants of FTO and IRX3 genes are in high linkage disequilibrium and are associated with obesity...
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F. M.; O'Rahilly, S.; Schofield, C. J. (2008). "The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science....
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mouse development, FTO has been shown to mediated LINE1 RNA m6A demethylation and consequently affect local chromatin state and nearby gene transcription....
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researchers described as the first clear genetic link, via the FTO gene, to obesity. Presence of the gene beyond that initial subject pool was not yet studied....
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mutations in the KSR2 gene are associated with insulin resistance and that genetic variation in the fat mass and obesity-associated protein (FTO) is associated...
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ISBN 9780511544699. Frayling, Timothy M. (May 11, 2007). "A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult...
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1965), Italian criminal clan boss nicknamed "'o Chiatto" (Fatso) FTO gene, or Fatso, a gene linked to obesity and type 2 diabetes Fatso the Fat-Arsed Wombat...
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(RBU). In 2010, work at the unit discovered that overexpression of the FTO gene led to obesity. The unit was in Oxfordshire. The unit carried out work...
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examining polymorphic variation in the fat mass and obesity associated FTO gene. With Aberdeen colleague Ela Krol, among others, he has published a series...
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Research Centre. Batterham identified that a genetic variation in the FTO gene can make people more likely to become obese. People with the obesity-risk...
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for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene". PLOS Genet. 5 (8): e1000599. doi:10.1371/journal.pgen.1000599. ISSN 1553-7404...
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Enhancer (genetics) (redirect from Gene enhancer)
Gómez-Marín C, et al. (March 2014). "Obesity-associated variants within FTO form long-range functional connections with IRX3". Nature. 507 (7492): 371–375...
52 KB (5,984 words) - 07:04, 5 August 2024
NPC1 (redirect from NPC1 (gene))
or responsible for obesity. These include genes such as MC4R, LEP, LEPR, and FTO. One of the lesser known gene diseases that is known to be linked to obesity...
24 KB (2,718 words) - 10:56, 11 April 2024
F. M.; O'Rahilly, S.; Schofield, C. J. (2007). "The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science....
23 KB (1,832 words) - 11:23, 4 February 2024
Thomas; Brüning, Jens C.; Rüther, Ulrich (2009). "Inactivation of the Fto gene protects from obesity". Nature. 458 (7240): 894–898. Bibcode:2009Natur...
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of eating styles (notably satiety sensitivity) and established that the FTO gene contributes to obesity in part through effects on eating behaviour styles...
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F. M.; O'Rahilly, S.; Schofield, C. J. (2007). "The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science....
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Lindgren, C. M.; Perry, J. R. B.; et al. (2007). "A Common Variant in the FTO Gene is Associated with Body Mass Index and Predisposes to Childhood and Adult...
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F. M.; O'Rahilly, S.; Schofield, C. J. (2007). "The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase". Science....
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RPGRIP1L (category Human chromosome 16 gene stubs)
the RPGRIP1L gene, rs3213758, is associated with increased BMI. Genetic variations strongly associated with obesity within the FTO gene have also been...
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Christine; Glunk, Viktoria; Sousa, Isabel S.; Kellis, Manolis (2015-09-03). "FTO Obesity Variant Circuitry and Adipocyte Browning in Humans". New England...
28 KB (2,678 words) - 15:23, 11 April 2024