Factor V Leiden (rs6025 or F5 p.R506Q) is a variant (mutated form) of human factor V (one of several substances that helps blood clot), which causes an...

hemorrhage, while some mutations (most notably factor V Leiden) predispose for thrombosis. The gene for factor V is located on the first chromosome (1q24)...

identified in 1965, while the most common abnormalities (including factor V Leiden) were described in the 1990s. The most common conditions associated...

clotting pathway mutations that increase the risk of clots include factor V Leiden. Prothrombin G20210A was identified in the 1990s. About 2% of Caucasians...

rates. Genetic factors include non-O blood type, deficiencies of antithrombin, protein C, and protein S and the mutations of factor V Leiden and prothrombin...

form is Factor V Leiden, which is responsible for more than 95% of cases. Other genetic causes include Factor V Cambridge (VThr306) and the factor V HR2 haplotype...

disorder called factor V Leiden. In factor V Leiden, a G1691A nucleotide replacement results in an R506Q amino acid mutation. Factor V Leiden increases the...

with normal plasma), coagulation factor assays, antiphospholipid antibodies, D-dimer, genetic tests (e.g. factor V Leiden, prothrombin mutation G20210A)...

County, Illinois, USA Leiden scale, for measuring extreme low temperatures. Factor V Leiden is named after the city of Leiden where it was discovered...

hormone therapy and hormonal contraceptives) Genetic thrombophilia (factor V Leiden, prothrombin mutation G20210A, protein C deficiency, protein S deficiency...

types Pheochromocytoma Livedoid vasculopathy and its association with factor V Leiden mutation FILS syndrome (polymerase ε1 mutation in a human syndrome...

polycythemia vera (high red blood cell counts), and is an additional risk factor for complications.[citation needed] A very small number of people report...

may be appropriate to check the antithrombin, protein C, protein S, factor V Leiden, prothrombin G20210A, and antiphospholipid antibodies.[citation needed]...

Prothrombin G20210A is not usually accompanied by other factor mutations (i.e., the most common is factor V Leiden). The gene may be inherited heterozygous (1 pair)...

Gurgey A. (1999). "Clinical manifestations in thrombotic children with factor V Leiden mutation". Pediatr Hematol Oncol. 16 (3): 233–237. doi:10.1080/088800199277281...

triad of Virchow (/ˈfɪərkoʊ/) describes the three broad categories of factors that are thought to contribute to thrombosis. Hypercoagulability Hemodynamic...

clotting disorders such as protein S deficiency, protein C deficiency, or factor V Leiden are also at increased risk of thrombophlebitis. Thrombophlebitis can...

autoimmune diseases such as lupus, various inherited thrombophilias such as Factor V Leiden, renal disease, multiple gestation (twins or multiple birth), and advanced...

to pulmonary embolism Ischemic stroke Hypercoagulable states (e.g., Factor V Leiden) — can lead to deep vein thrombosis Mechanical heart valves Myocardial...

OMIM. It can present in conjunction with protein S deficiency and factor V Leiden. It is not currently known if sticky platelet syndrome is a distinct...

(December 2017). "Laboratory assessment of Activated Protein C Resistance/Factor V-Leiden and performance characteristics of a new quantitative assay". Transfus...

hypercoagulability. Hereditary APC resistance is usually caused by the factor V Leiden mutation, whereas acquired APC resistance has been linked to antiphospholipid...

such as antiphospholipid antibodies, and congenital ones, including factor V Leiden, prothrombin mutation, proteins C and S deficiencies, and antithrombin...

such as Factor V Leiden, antiphospholipid syndrome), malignancy (such as pancreatic cancer) or metastasis, or a combination of these factors. In some...

Budd–Chiari syndrome. Factor V Leiden is responsible for 8% of cases. Other less common inherited disorders leading to the condition include factor II mutation...

might be involved in cancer progression. A SNP in the F5 gene causes Factor V Leiden thrombophilia. rs3091244 is an example of a triallelic SNP in the CRP...

vein. It most commonly affects leg veins, such as the femoral vein. Three factors are important in the formation of a blood clot within a deep vein—these...

characteristics. Other causes for thrombophilia are- Antiphospholipid syndrome, Factor V Leiden and Prothrombin G20210A mutations, protein C deficiency and antithrombin...

development of SVT, such as factor V Leiden, prothrombin 20210A mutation, and protein C, S, and antithrombin III and factor XII deficiency. The mechanism...

Thrombophilias (anti-phospholipid syndrome, protein C/S deficiency, factor V Leiden) Having donated a kidney Pregnancy Multiple gestation (twins or triplets...