• Thumbnail for Fas receptor
    The Fas receptor, also known as Fas, FasR, apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily...
    23 KB (2,675 words) - 19:25, 12 November 2023
  • Thumbnail for Fas ligand
    endothelial cells and natural killer (NK) cells. It binds with its receptor, called FAS receptor (also called CD95) and plays a crucial role in the regulation...
    22 KB (2,547 words) - 08:19, 11 August 2024
  • antigen leads to coexpression of Fas and Fas receptor on the T cell surface. The engagement of Fas by Fas receptor results in apoptosis of the cell and...
    8 KB (776 words) - 14:33, 15 August 2024
  • Look up FAS, Fas, or fas in Wiktionary, the free dictionary. Fas or FAS may refer to: Fez, Morocco, alternate spelling Poti, Georgia, a port city in Georgia...
    2 KB (278 words) - 15:48, 31 July 2024
  • Thumbnail for Activation-induced cell death
    programmed cell death caused by the interaction of Fas receptors (Fas, CD95) and Fas ligands (FasL, CD95 ligand). AICD is a negative regulator of activated...
    3 KB (434 words) - 20:08, 23 October 2022
  • Thumbnail for Alternative splicing
    membrane-bound form of the Fas receptor, which promotes apoptosis, or programmed cell death. Increased expression of Fas receptor in skin cells chronically...
    62 KB (7,809 words) - 17:56, 21 May 2024
  • Thumbnail for TNF receptor superfamily
    refers to those members of the TNF receptor superfamily that contain a death domain, such as TNFR1, Fas receptor, DR4 and DR5. They were named after...
    8 KB (501 words) - 13:55, 10 September 2024
  • Thumbnail for FADD
    protein that bridges members of the tumor necrosis factor receptor superfamily, such as the Fas-receptor, to procaspases 8 and 10 to form the death-inducing...
    34 KB (4,191 words) - 16:39, 21 December 2023
  • Thumbnail for Apoptosis
    uncontrolled cell proliferation, such as cancer. Some factors like Fas receptors and caspases promote apoptosis, while some members of the Bcl-2 family...
    91 KB (10,653 words) - 17:23, 6 September 2024
  • Thumbnail for Trypsin
    However Accutase decreases the surface levels of FasL and Fas receptor on macrophages, these receptors are associated with cell cytotoxicity in the immune...
    26 KB (2,827 words) - 03:08, 1 October 2024
  • progenitor cells and lymphocytes in the bone marrow over-express the Fas receptor, the main element in apoptotic signaling. A significant increase in the...
    40 KB (4,353 words) - 21:26, 6 September 2024
  • Thumbnail for Decoy receptor 3
    M68, is a soluble protein of the tumor necrosis factor receptor superfamily which inhibits Fas ligand-induced apoptosis. Dcr3 was identified in 1998 by...
    12 KB (1,243 words) - 23:39, 29 November 2023
  • Thumbnail for Butyric acid
    that is bound to the Fas gene promoter in T cells, resulting in hyperacetylation of the Fas promoter and up-regulation of Fas receptor on the T-cell surface...
    65 KB (6,434 words) - 21:47, 20 October 2024
  • Thumbnail for Death-inducing signaling complex
    complex formed by members of the death receptor family of apoptosis-inducing cellular receptors. A typical example is FasR, which forms the DISC upon trimerization...
    7 KB (993 words) - 08:12, 18 August 2023
  • Thumbnail for CCR5
    CCR5 (redirect from CCR5 receptor)
    C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it...
    67 KB (7,852 words) - 00:52, 17 October 2024
  • CXC chemokine receptors are integral membrane proteins that specifically bind and respond to cytokines of the CXC chemokine family. They represent one...
    9 KB (885 words) - 07:16, 30 April 2024
  • Thumbnail for Lupus
    other genes, i.e., NEIL3, TMEM173, ADAR1, NRAS, SAMHD1, SOS1, FASLG, FAS receptor gene, RAG1, RAG2, DNASE1, SHOC2, KRAS, PTPN11, PTEN, BLK, RNASEH2A, RNASEH2B...
    129 KB (14,190 words) - 06:36, 19 October 2024
  • Interleukin-1 receptor (IL-1R) is a cytokine receptor which binds interleukin 1. Two forms of the receptor exist. The type I receptor is primarily responsible...
    3 KB (244 words) - 17:53, 24 January 2023
  • of. The other pathway is the Fas ligand pathway. In this pathway, a Fas ligand (FasL) on the CTL binds to Fas receptor (FasR) on the target cell. This pathway...
    3 KB (416 words) - 08:59, 30 June 2024
  • Thumbnail for Interleukin-3 receptor
    coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes. The receptor belongs to the type I cytokine receptor family and...
    2 KB (206 words) - 15:30, 8 September 2024
  • Thumbnail for Erythropoietin receptor
    Additionally, EpoR has been implicated in suppressing expression of death receptors Fas, Trail and TNFa that negatively affect erythropoiesis. Based on current...
    28 KB (3,409 words) - 18:05, 8 June 2024
  • Thumbnail for Cell death
    interaction of Fas receptor (Fas, CD95)and Fas ligand (FasL, CD95 ligand). It occurs as a result of repeated stimulation of specific T-cell receptors (TCR) and...
    16 KB (1,909 words) - 19:13, 26 September 2024
  • Thumbnail for Sertoli cell
    part of the body. FAS/FAS-L system – expression of Fas ligand (Fas-L) on the surface of SCs activates apoptotic death of Fas receptor-bearing cells, e...
    26 KB (3,061 words) - 14:02, 25 September 2024
  • Thumbnail for Eosinophilia
    gene defect, and autoimmune lymphoproliferative syndrome (defective Fas receptor gene). More than 30 other primary immunodeficiency diseases are sometimes...
    50 KB (5,523 words) - 16:49, 13 October 2024
  • The prolactin receptor (PRLR) is a type I cytokine receptor encoded in humans by the PRLR gene on chromosome 5p13-14. It is the receptor for prolactin...
    17 KB (1,865 words) - 06:48, 21 December 2023
  • Thumbnail for Fetal alcohol spectrum disorder
    severe to least severe) are: fetal alcohol syndrome (FAS), partial fetal alcohol syndrome (pFAS), alcohol-related neurodevelopmental disorder (ARND),...
    138 KB (15,872 words) - 04:09, 19 October 2024
  • Thumbnail for Growth hormone receptor
    acids. The receptor is part of the Type I cytokine receptor family of receptors. GHR exists in two forms as a full length membrane-bound receptor and as a...
    18 KB (1,925 words) - 16:27, 31 March 2024
  • Thumbnail for IL-2 receptor
    The interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds...
    9 KB (934 words) - 16:50, 3 October 2024
  • Thumbnail for Ligand (biochemistry)
    the function of the receptor that triggers a physiological response is called a receptor agonist. Ligands that bind to a receptor but fail to activate...
    29 KB (3,166 words) - 21:19, 21 August 2024
  • Thumbnail for IL2RA
    The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2...
    23 KB (2,548 words) - 17:16, 27 August 2024