A first-in-class medication is a prototype drug that uses a "new and unique mechanism of action" to treat a particular medical condition. While the Food...

considers it to be a first-in-class medication. Angiotensin II is a vasoconstrictor used to increase blood pressure in adults with septic or other distributive...

Administration (FDA) considers it to be a first-in-class medication. It was approved by the FDA for weight loss in November 2023. In November 2023, the UK Medicines...

A drug class is a group of medications and other compounds that have similar chemical structures, the same mechanism of action (i.e. binding to the same...

a first-in-class medication. Tofersen is indicated to treat people with amyotrophic lateral sclerosis (ALS) associated with a mutation in the superoxide...

with paroxysmal nocturnal hemoglobinuria in December 2023. The FDA considers it to be a first-in-class medication. Iptacopan is indicated for the treatment...

Administration (FDA) considers it to be a first-in-class medication. Sparsentan is indicated to reduce proteinuria in people with primary immunoglobulin A...

considers it to be a first-in-class medication. In the US, bempedoic acid is indicated for the treatment of hypercholesterolemia in combination with diet...

use in the United States in May 2023 under the brand Miebo. The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. Perfluorohexyloctane...

protein in the liver via the RNAi pathway. Patisiran was developed and is marketed by Alnylam. The FDA considers it to be a first-in-class medication. Patisiran...

U.S. Food and Drug Administration considers it to be a first-in-class medication. In the United States, finerenone is indicated to reduce the risk of...

Administration (FDA) considers it to be a first-in-class medication. In December 2021, voxelotor received accelerated approval in the United States for the treatment...

Bremelanotide, sold under the brand name Vyleesi, is a medication used to treat low sexual desire in women. Specifically it is used for low sexual desire...

The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. Omaveloxolone is indicated for the treatment of Friedreich's...

Food and Drug Administration (FDA) considers it to be a first-in-class medication. In 2006, scientists from Purdue University designed a targeting ligand...

U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. Studies indicate that emicizumab is a better therapy compared...

to be a first-in-class medication. Fezolinetant is indicated for the treatment of moderate to severe vasomotor symptoms due to menopause. In September...

used in combination with fulvestrant. The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. Capivasertib, used in combination...

approved for medical use in the United States. The U.S. Food and Drug Administration considers it to be a first-in-class medication. In August 2023, the National...

Vyvgart, is a medication used to treat myasthenia gravis. Efgartigimod alfa is a neonatal Fc receptor blocker and is a new class of medication. It is an antibody...

for medical use in the United States in 2022. The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. Terlipressin is...

The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. Luspatercept is indicated for the treatment of adults with...

atopic dermatitis in 2017, and for asthma in 2018. The FDA considers it to be a first-in-class medication. Dupilumab is the first treatment for eosinophilic...

medical use in the United States in April 2022. The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. Mavacamten is...

for medical use in the United States in May 2022. The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. Tapinarof is...

medical use in the United States in September 2023. The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. Primary hyperoxaluria...

patented in 1969 and approved for medical use in 1985. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication for Duchenne...

2024. "U.S. Food and Drug Administration Approves Zelsuvmi as a First-in-Class Medication for the Treatment of Molluscum Contagiosum". Ligand Pharmaceuticals...

to be a first-in-class medication. In the United States, nirmatrelvir/ritonavir is indicated for the treatment of mild-to-moderate COVID‑19 in adults who...

and Drug Administration (FDA). The FDA considers it to be a first-in-class medication. In the United States, avacopan is indicated as an adjunctive treatment...