Flumazenil (also known as flumazepil, code name Ro 15-1788) is a selective GABAA receptor antagonist administered via injection, otic insertion, or intranasally...
23 KB (2,421 words) - 04:02, 12 January 2025
Narcolepsy (section Flumazenil)
improve sleepiness. These currently include clarithromycin and flumazenil. Flumazenil is the only GABAA receptor antagonist on the market as of January...
72 KB (8,224 words) - 16:08, 15 January 2025
Benzodiazepine overdose (section Flumazenil)
mainstay of treatment of benzodiazepine overdose. There is an antidote, flumazenil, but its use is controversial. Deaths from single-drug benzodiazepine...
37 KB (4,044 words) - 15:12, 21 November 2024
severe side effects include memory problems and hallucinations. While flumazenil, a GABAA–receptor antagonist, can reverse zolpidem's effects, usually...
68 KB (6,619 words) - 18:10, 9 February 2025
involved, the flumazenil detoxification method is controversial and can only be done as an inpatient procedure under medical supervision. Flumazenil was found...
87 KB (9,014 words) - 15:49, 9 February 2025
thienotriazolodiazepine, but produces very similar effects as benzodiazepines. Flumazenil is an imidazobenzodiazepine derivative, and in layman's terms, it is a...
108 KB (3,088 words) - 16:43, 19 December 2024
subsequently, the administration of flumazenil may result in seizures. Therefore, slow administration of flumazenil is necessary to prevent the occurrence...
6 KB (740 words) - 18:59, 21 June 2024
benzodiazepine) is flumazenil (Anexate). This drug is only used in cases with severe respiratory depression or cardiovascular complications. Because flumazenil is a...
103 KB (10,009 words) - 03:21, 10 February 2025
Coma cocktail (section Flumazenil)
D50W IV), flumazenil (0.2 mg IV), naloxone (2 mg IV), and thiamine (100 mg IV). It has been suggested that the use of naloxone and flumazenil be administered...
7 KB (809 words) - 06:09, 12 September 2024
improve sleepiness. These currently include clarithromycin and flumazenil. Flumazenil, a GABAA receptor antagonist is approved by the FDA for use in anesthesia...
48 KB (5,176 words) - 18:06, 12 January 2025
Benzodiazepine dependence (section Flumazenil)
3% of patients discontinuing benzodiazepines completely within a year. Flumazenil delivered via slow subcutaneous infusion represents a safe procedure for...
75 KB (8,852 words) - 05:46, 9 February 2025
benzodiazepines, the LD50 is still far beyond the prescribed or recommended dose. Flumazenil, a GABA antagonist agent used to reverse benzodiazepine overdoses, inhibits...
31 KB (2,835 words) - 00:08, 14 February 2025
the benzodiazepine antidote flumazenil. The main interest in Ro15-4513 was as an antidote to alcohol (ethanol). Flumazenil effectively blocks the effects...
9 KB (901 words) - 00:38, 17 October 2024
PMID 15214628. S2CID 39966201. "Treatment of benzodiazepine overdose with flumazenil. The Flumazenil in Benzodiazepine Intoxication Multicenter Study Group". Clinical...
164 KB (17,195 words) - 07:47, 15 February 2025
and liver damage. Its effect can be quickly reversed by the action of flumazenil, which is already used as an antidote to benzodiazepine overdose. Nutt...
8 KB (809 words) - 19:32, 11 January 2025
basis develop a dependence. Physiological dependence was demonstrated by flumazenil-precipitated withdrawal. Use of alcohol or other CNS depressants while...
78 KB (7,618 words) - 21:11, 11 January 2025
most closely related to other imidazobenzodiazepines such as midazolam, flumazenil, and bretazenil. Imidazenil is a highly potent benzodiazepine receptor...
8 KB (699 words) - 02:45, 2 February 2025
Anexate is the trade name of two different drugs: Flumazenil, a benzodiazepine antagonist Mefenorex, a stimulant drug which was used as an appetite suppressant...
192 bytes (55 words) - 16:49, 27 December 2019
consisting of a combination of gabapentin and two other medications (flumazenil and hydroxyzine) as well as therapy, is an ineffective treatment promoted...
101 KB (10,116 words) - 18:13, 16 February 2025
can be treated with the GABAA receptor benzodiazepine site antagonist flumazenil, which displaces zopiclone from its binding site, thereby rapidly reversing...
55 KB (6,030 words) - 03:17, 12 January 2025
contrast, most benzodiazepine overdose does not benefit from its antidote, flumazenil. Respiratory therapy/respiratory physiotherapy may be beneficial in some...
18 KB (1,806 words) - 03:06, 3 January 2025
which can range from six months to several years in more severe cases. Flumazenil was found to be more effective than placebo in reducing feelings of hostility...
22 KB (2,389 words) - 13:17, 11 February 2025
securinine and metrazol, and the benzodiazepine GABAA receptor antagonist flumazenil. Other agents which may have GABAA receptor antagonism include the antibiotic...
3 KB (315 words) - 21:55, 14 April 2024
if necessary, considering the hazards of doing so, giving intravenous flumazenil. People are ideally nursed in a kind, frustration-free environment, since...
83 KB (8,677 words) - 00:38, 24 January 2025
tranquillizer drugs before the development of newer antidotes such as flumazenil. It produces dimethylethanolamine as a metabolite.[citation needed] Meclofenoxate...
2 KB (110 words) - 02:39, 14 January 2025
abuse is manifested, an inpatient detoxification may be required, with flumazenil as a possible detoxification tool. Nonbenzodiazepine hypnotic drugs, similar...
33 KB (3,584 words) - 19:32, 27 January 2025
clomethiazole's action at the barbiturate complex the benzodiazepine antidote flumazenil cannot reverse the effects of overdose; overdose treatment is restricted...
9 KB (831 words) - 03:35, 12 January 2025
help combat any belief or fear that they were "awake" during anesthesia. Flumazenil, reverses the effects of benzodiazepines Naloxone, reverses the effects...
21 KB (2,208 words) - 22:22, 28 January 2025
psychologist, involved a combination of three medications (gabapentin, flumazenil and hydroxyzine) as well as therapy. While the individual drugs had been...
22 KB (2,293 words) - 05:30, 16 February 2025
Yajnik S, Coalson D, Lichtor JL, Apfelbaum JL, Rupani G, et al. (1995). "Flumazenil may attenuate some subjective effects of nitrous oxide in humans: a preliminary...
95 KB (9,860 words) - 23:12, 9 February 2025