In molecular biology, foldases are a particular kind of molecular chaperones that assist the non-covalent folding of proteins in an ATP-dependent manner...

refolding them. They stand in opposition to foldases, which are chaperones that use ATP to fold proteins. Foldase Chaperonin Co-chaperone Hoffmann, J. R....

cytosol of eukaryotes, and in mitochondria. Some chaperone systems work as foldases: they support the folding of proteins in an ATP-dependent manner (for example...

PMID 13683522. Kris Pauwels and other (2007). "Chaperoning Anfinsen:The Steric Foldases" (PDF). Molecular Microbiology. 64 (4): 917–922. doi:10.1111/j.1365-2958...

initiation of the UPR. BiP can actively fold its substrates (acting as a foldase) or simply bind and restrict a substrate from folding or aggregating (acting...

a rate limiting step in protein folding. PrsA homologs also contain a foldase domain suspected to aid in the folding of proteins but, unlike the parvulin...

substrate protein (step 3). Protein disulfide isomerase (PDI), a resident foldase of the endoplasmic reticulum, is a multi-functional protein that catalyses...

demonstrated that the apo state of the chaperonin GroEL possesses intrinsic foldase/unfoldase activities." Clore played a pivotal role in the development of...

proteins such as P3H1, CRTAP, BiP, GRP94, PDI, and calreticulin to form foldase and chaperone complexes and facilitate protein folding, especially for...

to the multiple myeloma treatment bortezomib (Btz) by impacting BiP's foldase and ATPase activities. In another collaborative study published in Scientific...