• Genome-wide complex trait analysis (GCTA) Genome-based restricted maximum likelihood (GREML) is a statistical method for heritability estimation in genetics...
    32 KB (3,510 words) - 17:14, 5 June 2024
  • Thumbnail for Complex traits
    studied with statistical techniques like quantitative trait loci (QTL) mapping, and genome-wide association studies (GWAS) on a large scale. The overall...
    27 KB (2,719 words) - 19:59, 11 September 2024
  • Thumbnail for Genome-wide association study
    In genomics, a genome-wide association study (GWA study, or GWAS), is an observational study of a genome-wide set of genetic variants in different individuals...
    69 KB (6,790 words) - 03:14, 15 July 2024
  • for genome-wide interaction analysis (GWIA) of case-control SNP data and analysis of quantitative traits Precision Mapping of Quantitative Trait Loci...
    33 KB (3,825 words) - 00:32, 21 October 2024
  • Thumbnail for Heritability
    Heritability (redirect from Heritable trait)
    Goddard ME, Visscher PM (January 2011). "GCTA: a tool for genome-wide complex trait analysis". American Journal of Human Genetics. 88 (1): 76–82. doi:10...
    47 KB (5,648 words) - 19:13, 19 November 2024
  • examining both human and pig quantitative trait loci through a method known as genome-wide complex trait analysis (GCTA), which allowed the researchers to...
    23 KB (2,679 words) - 22:04, 2 December 2023
  • using mixed effects models implemented in software such as genome-wide complex trait analysis (GCTA). To do this, researchers find the average genetic relatedness...
    83 KB (8,036 words) - 11:54, 24 November 2024
  • Thumbnail for Polygenic score
    individual's phenotype. The PGS is also called the polygenic index (PGI) or genome-wide score; in the context of disease risk, it is called a polygenic risk...
    59 KB (6,725 words) - 04:30, 29 July 2024
  • Gene-environment interaction Gene-environment correlation Genome-wide complex trait analysis Heritability Heritability of IQ Human nature Identical Strangers:...
    65 KB (7,725 words) - 22:03, 23 September 2024
  • was supported by the introduction of Genome-wide complex trait analysis (GCTA) in 2010, which demonstrated that trait similarity could be predicted by the...
    20 KB (2,295 words) - 07:11, 6 August 2024
  • personality traits, also known as the five-factor model (FFM) or the OCEAN model, is the prevailing model for personality traits. When factor analysis (a statistical...
    24 KB (2,999 words) - 20:14, 18 December 2023
  • times. Microsatellites occur at thousands of locations within an organism's genome. They have a higher mutation rate than other areas of DNA leading to high...
    67 KB (7,394 words) - 16:46, 2 September 2024
  • prioritization of candidate causal genes in candidate gene analysis following genome-wide association studies. TWAS looks at the RNA products of a specific...
    22 KB (2,971 words) - 02:30, 1 December 2023
  • Daly; Hirschhorn, Joel N. (2005-02-01). "Genome-wide association studies for common diseases and complex traits". Nature Reviews Genetics. 6 (2): 95–108...
    30 KB (3,953 words) - 20:23, 16 September 2024
  • Thumbnail for Genome
    children. Bacterial genome size Cryoconservation of animal genetic resources Genome Browser Genome Compiler Genome topology Genome-wide association study...
    80 KB (7,349 words) - 03:33, 21 November 2024
  • Thumbnail for Metagenomics
    Function-driven analysis seeks to identify clones expressing a desired trait or useful activity, followed by biochemical characterization and sequence analysis. This...
    88 KB (9,198 words) - 18:29, 3 November 2024
  • Thumbnail for Single-nucleotide polymorphism
    R.; Jaffe, Andrew E. (2021-09-02). "Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia...
    58 KB (6,240 words) - 04:24, 29 September 2024
  • Thumbnail for Michael Goddard
    Goddard, M. E.; Visscher, P. M. (2011). "GCTA: A tool for genome-wide complex trait analysis". The American Journal of Human Genetics. 88 (1): 76–82. doi:10...
    11 KB (783 words) - 06:00, 20 March 2023
  • Thumbnail for Genetics
    Genetics (redirect from Genetic trait)
    to look for locations in the genome that are associated with diseases, a method especially useful for multigenic traits not clearly defined by a single...
    98 KB (10,409 words) - 22:59, 14 November 2024
  • In bioinformatics, sequence analysis is the process of subjecting a DNA, RNA or peptide sequence to any of a wide range of analytical methods to understand...
    33 KB (3,894 words) - 07:15, 23 July 2024
  • in validation of genome-wide association study (GWAS) results, breeding, prediction of traits, and discovering the etiology of traits & diseases. They...
    50 KB (5,821 words) - 04:35, 8 July 2024
  • polymorphism heritability of behavior problems in childhood: genome-wide complex trait analysis". Journal of the American Academy of Child & Adolescent Psychiatry...
    19 KB (2,246 words) - 15:31, 11 December 2023
  • Thumbnail for Epigenome-wide association study
    An epigenome-wide association study (EWAS) is an examination of a genome-wide set of quantifiable epigenetic marks, such as DNA methylation, in different...
    32 KB (3,597 words) - 15:04, 21 April 2024
  • Thumbnail for Gene–environment interaction
    through genome wide approaches. A particular concern with gene–environment interaction studies is the lack of reproducibility. Specifically complex traits studies...
    36 KB (4,404 words) - 01:51, 27 January 2024
  • Thumbnail for Bioinformatics
    provides. Genome-wide association studies have successfully identified thousands of common genetic variants for complex diseases and traits; however,...
    133 KB (8,447 words) - 15:20, 9 November 2024
  • Thumbnail for Genomics
    Genomics (redirect from Genome biology)
    affecting more than one trait), heterosis (hybrid vigour), and other interactions between loci and alleles within the genome. From the Greek ΓΕΝ gen,...
    79 KB (7,635 words) - 19:55, 14 November 2024
  • Thumbnail for Whole genome sequencing
    (August 2016). "Genome-wide association study using whole-genome sequencing rapidly identifies new genes influencing agronomic traits in rice". Nature...
    113 KB (9,500 words) - 04:44, 27 September 2024
  • Thumbnail for Functional genomics
    structures. A key characteristic of functional genomics studies is their genome-wide approach to these questions, generally involving high-throughput methods...
    32 KB (4,013 words) - 04:45, 28 May 2024
  • Thumbnail for Genome editing
    Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the...
    78 KB (9,361 words) - 01:20, 25 September 2024
  • Thumbnail for CRISPR gene editing
    CRISPR gene editing (category Genome editing)
    system. By delivering the Cas9 nuclease complexed with a synthetic guide RNA (gRNA) into a cell, the cell's genome can be cut at a desired location, allowing...
    170 KB (19,890 words) - 19:36, 10 November 2024