• Glia maturation factor is a neurotrophic factor implicated in nervous system development, angiogenesis and immune function. In humans, the glia maturation...
    2 KB (115 words) - 20:48, 18 October 2022
  • neurotrophic factors include: glia maturation factor, insulin, insulin-like growth factor 1 (IGF-1), vascular endothelial growth factor (VEGF), fibroblast...
    16 KB (1,784 words) - 04:08, 6 January 2024
  • Thumbnail for Nerve growth factor
    Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
    27 KB (3,064 words) - 04:17, 25 November 2024
  • Thumbnail for NF-κB
    (December 2001). "Effects of glia maturation factor overexpression in primary astrocytes on MAP kinase activation, transcription factor activation, and neurotrophin...
    89 KB (9,773 words) - 11:16, 4 October 2024
  • Thumbnail for Glucose-6-phosphate isomerase
    called autocrine motility factor and stimulates metastasis. Extracellular GPI is also known to function as a maturation factor. Though originally treated...
    27 KB (3,057 words) - 12:53, 9 September 2024
  • Thumbnail for Epidermal growth factor
    Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
    17 KB (1,708 words) - 22:30, 15 October 2024
  • Thumbnail for Brain-derived neurotrophic factor
    Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin...
    46 KB (5,344 words) - 17:28, 12 October 2024
  • Thumbnail for Platelet-derived growth factor
    Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
    24 KB (2,882 words) - 16:31, 25 October 2024
  • Thumbnail for Receptor tyrosine kinase
    are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90 unique tyrosine kinase genes identified...
    28 KB (3,078 words) - 07:46, 3 June 2024
  • Thumbnail for Neurotrophin
    to a class of growth factors, secreted proteins that can signal particular cells to survive, differentiate, or grow. Growth factors such as neurotrophins...
    27 KB (3,078 words) - 19:34, 17 October 2024
  • promote cell differentiation and maturation, which varies between growth factors. For example, epidermal growth factor (EGF) enhances osteogenic differentiation...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
    40 KB (4,578 words) - 12:30, 10 September 2024
  • Thumbnail for Epidermal growth factor receptor
    growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
    60 KB (6,879 words) - 14:26, 16 July 2024
  • Thumbnail for Insulin-like growth factor 1
    Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in...
    35 KB (4,575 words) - 09:00, 2 November 2024
  • Thumbnail for Testosterone
    strength, and stimulation of linear growth and bone maturation. Androgenic effects include maturation of the sex organs, particularly the penis, and the...
    149 KB (15,703 words) - 10:37, 23 November 2024
  • Thumbnail for Hepatocyte growth factor
    Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells...
    23 KB (2,635 words) - 06:03, 24 August 2024
  • Transforming growth factor ([attribution needed], or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ. The name "Transforming...
    6 KB (596 words) - 05:15, 1 January 2024
  • growth factor receptors (FGFRs). FGF1 is also known as acidic fibroblast growth factor, and FGF2 is also known as basic fibroblast growth factor. Members...
    25 KB (3,124 words) - 21:38, 18 August 2024
  • Thumbnail for Dexamethasone
    Dexamethasone may be given to women at risk of delivering prematurely to promote maturation of the fetus's lungs. This administration, given from one day to one week...
    72 KB (6,433 words) - 04:45, 17 November 2024
  • Thumbnail for Nintedanib
    targeting vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Ofev was developed by...
    34 KB (3,021 words) - 12:39, 5 August 2024
  • neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF). Although...
    13 KB (1,177 words) - 01:44, 4 November 2024
  • Thumbnail for Lenvatinib
    endothelial growth factor receptors VEGFR1, 2 and 3, as well as fibroblast growth factor receptors (FGFR) 1, 2, 3 and 4, platelet-derived growth factor receptor...
    11 KB (934 words) - 11:38, 21 October 2024
  • Thumbnail for Adult neurogenesis
    example, NeuN/Fox3 and GFAP are antigens commonly used to detect neurons, glia, and ependymal cells. Ki67 is the most commonly used antigen to detect cell...
    105 KB (12,338 words) - 00:34, 29 September 2024
  • Thumbnail for Osimertinib
    carcinomas with specific mutations. It is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor. The most common side effects include...
    18 KB (1,573 words) - 05:19, 15 October 2024
  • Thumbnail for Cetuximab
    Cetuximab, sold under the brand name Erbitux, is an epidermal growth factor receptor (EGFR) inhibitor medication used for the treatment of metastatic colorectal...
    26 KB (2,420 words) - 02:40, 26 September 2024
  • Thumbnail for Erythropoietin
    Erythropoietin (category Growth factors)
    Erythropoietin is the primary erythropoietic factor that cooperates with various other growth factors (e.g., IL-3, IL-6, glucocorticoids, and SCF) involved...
    31 KB (3,421 words) - 06:52, 2 November 2024
  • Thumbnail for Insulin-like growth factor
    The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
    14 KB (1,689 words) - 01:31, 19 August 2024
  • Thumbnail for Vascular endothelial growth factor A
    growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. This gene is a member of the platelet-derived growth factor (PDGF)/vascular...
    24 KB (3,053 words) - 21:43, 17 August 2024
  • Thumbnail for Tyrosine kinase
    endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), stem cell factor receptor, and colony-stimulating factor-1 receptor...
    43 KB (5,251 words) - 10:44, 24 June 2024
  • growth factor therapy, also known as anti-VEGF (/vɛdʒˈɛf/) therapy or medication, is the use of medications that block vascular endothelial growth factor. This...
    14 KB (1,693 words) - 18:18, 18 October 2024