• Thumbnail for Glucuronide
    A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond. The glucuronides...
    2 KB (173 words) - 16:11, 19 October 2024
  • Thumbnail for Ethyl glucuronide
    Ethyl glucuronide (EtG) is a metabolite of ethanol which is formed in the body by glucuronidation following exposure to ethanol, usually from drinking...
    9 KB (929 words) - 13:26, 17 March 2024
  • Thumbnail for Bilirubin glucuronide
    Bilirubin glucuronide is a water-soluble reaction intermediate over the process of conjugation of indirect bilirubin. Bilirubin glucuronide itself belongs...
    30 KB (2,694 words) - 12:35, 16 July 2024
  • Quercetin glucuronide or Quercetol glucuronide may refer to: Quercetin 3-O-glucuronide Quercetin 3'-O-glucuronide Flavonoid glucuronides are substrates...
    460 bytes (97 words) - 22:35, 25 August 2021
  • Thumbnail for Bromazolam
    bromazolam N-glucuronide, phenyl-hydroxy bromazolam glucuronide, α-hydroxy bromazolam glucuronide, and 4-hydroxy bromazolam glucuronide. In the blood...
    19 KB (2,022 words) - 23:29, 11 September 2024
  • Thumbnail for Morphine-6-glucuronide
    Morphine-6-glucuronide (M6G) is a major active metabolite of morphine. M6G is formed from morphine by the enzyme UGT2B7. It has analgesic effects more...
    7 KB (567 words) - 16:30, 21 October 2024
  • Thumbnail for Androstanediol glucuronide
    3α-Androstanediol glucuronide (3α-ADG) is a metabolite formed from human androgens; compounds involved in the development and maintenance of sexual characteristics...
    4 KB (259 words) - 05:28, 21 February 2024
  • Thumbnail for Estrogen conjugate
    3-glucuronide (E1-G) Estradiol 3-glucuronide (E2-3G) and estradiol 17β-glucuronide (E2-17G) Estriol 3-glucuronide (E3-3G), estriol 16α-glucuronide (E3-16G)...
    3 KB (221 words) - 00:06, 4 September 2022
  • Thumbnail for Testosterone glucuronide
    Testosterone glucuronide is an endogenous, naturally occurring steroid and minor urinary metabolite of testosterone. Androstanediol glucuronide Androsterone...
    2 KB (120 words) - 19:07, 7 May 2023
  • Thumbnail for Lorazepam
    conjugated at its 3-hydroxy group into lorazepam glucuronide which is then excreted in the urine. Lorazepam glucuronide has no demonstrable CNS activity in animals...
    82 KB (8,641 words) - 21:44, 16 October 2024
  • Thumbnail for Androsterone glucuronide
    Androsterone glucuronide (ADT-G) is a major circulating and urinary metabolite of testosterone and dihydrotestosterone (DHT). It accounts for 93% of total...
    3 KB (119 words) - 22:41, 28 April 2023
  • In enzymology, a luteolin-7-O-glucuronide 2"-O-glucuronosyltransferase (EC 2.4.1.190) is an enzyme that catalyzes the chemical reaction UDP-glucuronate...
    2 KB (196 words) - 18:22, 23 January 2024
  • Thumbnail for Estrone glucuronide
    Estrone glucuronide, or estrone-3-D-glucuronide, is a conjugated metabolite of estrone. It is formed from estrone in the liver by UDP-glucuronyltransferase...
    5 KB (367 words) - 03:04, 1 May 2023
  • Thumbnail for Bilirubin diglucuronide
    Bilirubin di-glucuronide is a conjugated form of bilirubin formed in bilirubin metabolism. The hydrophilic character of bilirubin diglucuronide enables...
    4 KB (135 words) - 12:35, 16 July 2024
  • Thumbnail for Codeine-6-glucuronide
    Codeine-6-glucuronide (C6G) is a major active metabolite of codeine and may be responsible for as much as 60% of the analgesic effects of codeine. C6G...
    3 KB (176 words) - 11:20, 21 October 2024
  • Thumbnail for Estriol glucuronide
    Estriol glucuronide (E3G), or oestriol glucuronide, also known as estriol monoglucuronide, as well as estriol 16α-β-D-glucosiduronic acid, is a natural...
    8 KB (588 words) - 04:50, 2 October 2023
  • Thumbnail for Estradiol glucuronide
    Estradiol glucuronide, or estradiol 17β-D-glucuronide, is a conjugated metabolite of estradiol. It is formed from estradiol in the liver by UDP-glucuronyltransferase...
    10 KB (874 words) - 15:35, 11 March 2024
  • Thumbnail for Sulfamethoxazole
    5-methylhydroxy-, N4-acetyl-5-methylhydroxy-sulfamethoxazole metabolites, and an N-glucuronide conjugate. The CYP2C9 enzyme is responsible for the formation of the...
    12 KB (982 words) - 15:35, 8 October 2024
  • Thumbnail for Morphine-3-glucuronide
    Morphine-3-glucuronide is a metabolite of morphine produced by UGT2B7. It is not active as an opioid agonist, but does have some action as a convulsant...
    4 KB (296 words) - 00:38, 5 May 2023
  • Thumbnail for Catechin
    Catechin /ˈkætɪtʃɪn/ is a flavan-3-ol, a type of secondary metabolite providing antioxidant roles in plants. It belongs to the subgroup of polyphenols...
    38 KB (3,561 words) - 13:44, 12 October 2024
  • Thumbnail for Buprenorphine-3-glucuronide
    Buprenorphine-3-glucuronide (B3G) is a major active metabolite of the opioid modulator buprenorphine. It has affinity for the μ-opioid receptor (Ki =...
    4 KB (238 words) - 16:53, 28 April 2024
  • Thumbnail for Glucuronic acid
    hydroxyl groups. This linkage process is known as glucuronidation (or glucuronide conjugation). Glucuronidation occurs mainly in the liver, although the...
    17 KB (1,882 words) - 14:14, 7 August 2024
  • Thumbnail for Estriol 3-glucuronide
    Estriol 3-glucuronide, or oestriol 3-glucuronide, also known as estriol 3-β-D-glucosiduronic acid, is a natural, steroidal estrogen and a glucuronic acid...
    4 KB (202 words) - 21:33, 15 September 2023
  • The enzyme mycophenolic acid acyl-glucuronide esterase (EC 3.1.1.93, mycophenolic acid acyl-glucuronide deglucuronidase; AcMPAG deglucuronidase; systematic...
    6 KB (740 words) - 00:43, 24 August 2023
  • Thumbnail for Silodosin
    metabolite is silodosin glucuronide, which inhibits the α1A receptor with 1/8 of the affinity of the parent substance. 91% of the glucuronide are bound to plasma...
    15 KB (1,151 words) - 20:15, 6 October 2024
  • Thumbnail for Desloratadine
    3-hydroxylation of desloratadine N-glucuronide by CYP2C8; and finally, a non-enzymatic deconjugation of 3-hydroxydesloratadine N-glucuronide. Both desloratadine and...
    14 KB (1,039 words) - 04:17, 1 June 2024
  • Thumbnail for Ezetimibe
    extensively conjugated to a phenolic glucuronide (active metabolite). Mean Cmax (45–71 ng/ml) of ezetimibe-glucuronide is attained within 1–2 hours. The...
    20 KB (1,874 words) - 10:04, 21 October 2024
  • Thumbnail for Norbuprenorphine-3-glucuronide
    Norbuprenorphine-3-glucuronide (N3G) is a major active metabolite of the opioid modulator buprenorphine. It has affinity for the κ-opioid receptor (Ki...
    4 KB (228 words) - 18:03, 21 October 2024
  • Thumbnail for Quercetin
    metabolites (quercetin glucuronides) have been found in human plasma after quercetin ingestion. Taken together, the quercetin glucuronides have a half-life...
    26 KB (2,467 words) - 14:07, 12 September 2024
  • Thumbnail for SN-38
    then less easily excreted from the body in its SN-38 glucuronide form. SN-38 and its glucuronide are lost into the bile and intestines. It can cause the...
    3 KB (225 words) - 16:48, 11 January 2024