The ascorbate-glutathione cycle, sometimes Foyer-Halliwell-Asada pathway, is a metabolic pathway that detoxifies hydrogen peroxide (H2O2), a reactive...

component of the glutathione-ascorbate cycle, a system that reduces poisonous hydrogen peroxide. It is the precursor of phytochelatins, glutathione oligomers...

state of the NMDA receptor complex. Glutathione-ascorbate cycle Antioxidant Meister A, Anderson ME (1983). "Glutathione". Annual Review of Biochemistry....

reduced glutathione participates in the glutathione-ascorbate cycle in which reduced glutathione reduces dehydroascorbate, a reactive byproduct of the...

dehydroascorbic acid and ascorbate. APX is an integral component of the glutathione-ascorbate cycle. APX enzymes show high specificity for ascorbate as an electron...

other metabolites and enzyme systems, such as ascorbate in the glutathione-ascorbate cycle, glutathione peroxidases and glutaredoxins, as well as reacting...

vitamin E and vitamin C. In mild cases, ascorbate and N-acetylcysteine have been shown to increase glutathione levels and increase erythrocyte production...

monodehydroascorbate reductase (MDAR) is an enzymatic component of the glutathione-ascorbate cycle that is one of the major antioxidant systems of plant cells for...

dehydroascorbate reductase activity and may function in the glutathione-ascorbate cycle as part of antioxidant metabolism. GRCh38: Ensembl release 89:...

hydroperoxides. Glutathione functions as reductant in the enzymatic detoxification of reactive oxygen species in the glutathione-ascorbate cycle and as thiol...

where with Christine Foyer and others in 1976, he discovered the glutathione–ascorbate cycle (also known as the Foyer–Halliwell–Asada pathway) by which chloroplasts...

by glutathione to reform minoxidil. Such a process would cycle until the minoxidil is otherwise metabolized and would result in rapid glutathione depletion...

oxidative stress. It reduces glutathione via glutathione reductase, which converts reactive H2O2 into H2O by glutathione peroxidase. If absent, the H2O2...

Crohn's disease. Glutamine maintains redox balance by participating in glutathione synthesis and contributing to anabolic processes such as lipid synthesis...

testis, have a large concentration of antioxidants such as vitamin C (ascorbate) and β-carotene and anti-oxidant enzymes. If too much damage is present...

include cytochrome P450 oxidases, UDP-glucuronosyltransferases, and glutathione S-transferases. This system of enzymes acts in three stages to firstly...

thioredoxin-like proteins, or possibly glutathione, whereas the 1-Cys enzymes may be reduced by ascorbic acid or glutathione in the presence of GST-π. Using...

enzymes such as superoxide dismutase, the components of the ascorbate-glutathione cycle, and the NADP-dehydrogenases of the pentose-phosphate pathway...

depletion of intracellular ascorbate. The addition of ascorbate to the culture medium increased the intracellular ascorbate level and reversed both the...

antioxidants, including vitamin E, coenzyme Q10, ascorbate, carotenoids, superoxide dismutase, catalase, and glutathione peroxidase. These antioxidants provide...

methylglyoxal, then to pyruvate, or to D-lactaldehyde (via S-D-lactoyl-glutathione or otherwise) then D-lactate. D-lactate metabolism (to glucose) is slow...

oxidative stress. The synthesis of enzymes such as superoxide dismutase, L-ascorbate oxidase, and Delta 1 DNA polymerase is initiated in plants with the activation...

mutations in the enzyme prolyl hydroxylase or lack of the necessary ascorbate (vitamin C) cofactor. Peptide bonds to proline, and to other N-substituted...

Nanoparticles Phytotoxicity in Wheat Seedlings: Implication of the Ascorbate–Glutathione Cycle". Frontiers in Plant Science. 8: 1. doi:10.3389/fpls.2017.00001...

scavenging enzymes including: catalase, superoxide dismutase, glutathione reductase, and ascorbate peroxidase (to scavenge hydrogen peroxide). After conducting...

dismutase) and hydrogen peroxide-scavenging enzymes (catalase, ascorbate peroxidase, and glutathione peroxidase). The antioxidant superoxide dismutase catalyses...