• Glutathione hydrolase (EC 3.4.19.13, glutathionase, GGT, gamma-glutamyltranspeptidase) is an enzyme. This enzyme catalyses the following chemical reaction...
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  • hydrolase (EC 3.1.2.6, systematic name = S-(2-hydroxyacyl)glutathione hydrolase) catalyzes the following reaction: S-(2-hydroxyacyl)glutathione + H2O...
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  • enzyme hydroxymethylglutaryl-CoA hydrolase (EC 3.1.2.5) catalyzes the reaction S-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate This...
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  • reaction between a peptide and an amino acid Glutathione hydrolase, an enzyme that hydrolyzes glutathione A codon for the amino acid Glycine Germline gene...
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  • S-succinylglutathione hydrolase (EC 3.1.2.13) catalyzes the reaction S-succinylglutathione + H2O ⇌ {\displaystyle \rightleftharpoons } glutathione + succinate This...
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  • of hydrolases, specifically those acting on thioester bonds. The systematic name is S-acylglutathione hydrolase. It is also called citryl-glutathione thioesterhydrolase...
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  • Epoxide hydrolase In subsequent phase II reactions, these activated xenobiotic metabolites are conjugated with charged species such as glutathione (GSH)...
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  • S-formylglutathione hydrolase (EC 3.1.2.12) catalyzes the reaction S-formylglutathione + H2O ⇌ {\displaystyle \rightleftharpoons } glutathione + formate This...
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  • Gamma-glutamyltranspeptidase may refer to: Gamma-glutamyl transpeptidase, an enzyme Glutathione hydrolase, an enzyme This set index page lists enzyme articles associated...
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  • Thumbnail for Microsomal glutathione S-transferase 1
    To-Figueras J, Gené M, Gómez-Catalán J (2003). "Microsomal epoxide hydrolase and glutathione S-transferase polymorphisms in relation to laryngeal carcinoma...
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  • Thumbnail for Gamma-glutamyltransferase 6
    peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because...
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  • Thumbnail for Microsomal epoxide hydrolase
    In enzymology, a microsomal epoxide hydrolase (mEH) (EC 3.3.2.9) is an enzyme that catalyzes the hydrolysis reaction between an epoxide and water to form...
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  • Thumbnail for HAGH
    Hydroxyacylglutathione hydrolase, mitochondrial is an enzyme that in humans is encoded by the HAGH gene. The enzyme encoded by this gene is classified...
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  • Thumbnail for Gamma-glutamyltransferase 1
    gamma-glutamyltransferase catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. This heteroduplex...
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  • Thumbnail for Cytosol nonspecific dipeptidase
    extracellular exosome nucleoplasm cytoplasm cytosol Biological process metabolism glutathione biosynthetic process proteolysis Sources:Amigo / QuickGO...
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  • 6-oxide hydrolase Hepoxilin-epoxide hydrolase Isochorismatase Leukotriene-A4 hydrolase Limonene-1,2-epoxide hydrolase Microsomal epoxide hydrolase Trans-epoxysuccinate...
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  • Thumbnail for Gamma-glutamyltransferase 7
    is a membrane-associated protein involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of...
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  • pyroglutamate hydrolase, pyroglutamic hydrolase, L-pyroglutamate hydrolase, 5-oxo-L-prolinase, and pyroglutamase. This enzyme participates in glutathione metabolism...
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  • Thumbnail for Maleylacetoacetate isomerase
    cofactor glutathione to function. Ser 15, Cys 16, Gln 111, and the helix dipole of alpha 1 of the enzyme stabilize the thiolate form of glutathione which...
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  • Thumbnail for Gamma-glutamyltransferase 5
    a light chain and is able to hydrolyze the gamma-glutamyl moiety of glutathione. It converts leukotriene C4 to leukotriene D4, however, it doesn't convert...
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  • Thumbnail for Lactoylglutathione lyase
    (R)-S-lactoylglutathione is split into glutathione and D-lactate, is carried out by glyoxalase II, a hydrolase. Unusually, these reactions carried out...
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  • Thumbnail for Leukotriene
    residue of glutathione, LTF4 lacks the glycine residue of glutathione. LTB4 is synthesized in vivo from LTA4 by the enzyme LTA4 hydrolase. Its primary...
    18 KB (1,957 words) - 18:25, 30 March 2024
  • Thumbnail for Leukotriene C4 synthase
    encoded by this gene, LTC4S (or glutathione S-transferase II) is an enzyme that converts leukotriene A4 and glutathione to create leukotriene C4. This...
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  • List of EC numbers (EC 3) (category Hydrolases)
    EC 3.4.19.12: ubiquitinyl hydrolase 1 EC 3.4.19.13: glutathione γ-glutamate hydrolase EC 3.4.19.14: leukotriene-C4 hydrolase EC 3.4.19.15: desampylase...
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  • \rightleftharpoons } glutathione + spermidine Thus, the two substrates of this enzyme are glutathionylspermidine and H2O, whereas its two products are glutathione and...
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  • Thumbnail for EPHX1
    Epoxide hydrolase 1 is an enzyme encoded by the EPHX1 gene in humans. Epoxide hydrolase plays an important role in both the activation and detoxification...
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  • Thumbnail for Glycidamide
    glycidamide-glutathione conjugates. Both an enzymatic pathway via glutathione-S-transferase and a non-enzymatic pathway exist. These glycidamide-glutathione conjugates...
    11 KB (1,276 words) - 05:00, 26 January 2024
  • Thumbnail for Catalytic triad
    active site of some enzymes. Catalytic triads are most commonly found in hydrolase and transferase enzymes (e.g. proteases, amidases, esterases, acylases...
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  • Thumbnail for Paracetamol
    another paracetamol metabolite 4-aminophenol by action of fatty acid amide hydrolase. AM404 is a weak agonist of cannabinoid receptors CB1 and CB2, an inhibitor...
    123 KB (12,218 words) - 13:01, 4 October 2024
  • Thumbnail for Rhodanese
    DUSP2; DUSP4; DUSP5; DUSP6; DUSP7; DUSP10; DUSP16, aka MKP7; Thiosulfate:glutathione sulfurtransferase: KAT, now known as "TSTD1"; Adenylyltransferase and...
    6 KB (637 words) - 00:28, 8 December 2023