A growth cone is a large actin-supported extension of a developing or regenerating neurite seeking its synaptic target. It is the growth cone that drives...
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framework is that when a growth cone "senses" a guidance cue, the receptors activate various signaling molecules in the growth cone that eventually affect...
33 KB (4,365 words) - 15:00, 15 June 2024
are known as scales. The umbo of a conifer cone refers to the first year's growth of a seed scale on the cone, showing up as a protuberance at the end of...
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Axon (section Development and growth)
network in a growth cone will promote its neurite to become the axon. Growing axons move through their environment via the growth cone, which is at the...
58 KB (6,926 words) - 08:35, 7 August 2024
receptor on growth cones of the RGC axon. This morphogen initially attracts RGC axons, but then, through an internal change in the growth cone of the RGC...
29 KB (3,521 words) - 03:39, 17 June 2024
protoplasm called a growth cone, studded with chemical receptors. These receptors sense the local environment, causing the growth cone to be attracted or...
132 KB (15,613 words) - 14:37, 4 September 2024
Look up cone or coning in Wiktionary, the free dictionary. A cone is a basic geometrical shape. Cone may also refer to: Cone (category theory) Cone (formal...
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on growth cone spreading. Additionally, EphA receptors were shown to exert opposite effects on motor neuron growth cones by reducing growth cone size...
10 KB (1,211 words) - 05:21, 18 October 2022
development and play important roles in axon formation from neurites and in growth cone guidance and collapse through their interactions with microtubules. Cleaved...
21 KB (2,518 words) - 22:06, 10 December 2023
presence of laminin-1 can influence how the growth cone responds to other cues. For example, growth cones are repelled by netrin when grown on laminin-111...
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The growth cone is a highly dynamic structure of the developing neuron, changing directionality in response to different secreted and contact-dependent...
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involved in growth and proliferation. Neurotrophic factors act through retrograde transport in neurons, in which they are taken up by the growth cone of the...
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hedgehog (Shh) and Wnt. This navigation is mediated by the neuronal growth cone, a structure that responds to the cues by ligand-receptor signalling...
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force provides a mechanism for the growth cone to respond to direction cue, thereby directing neuronal axons. Growth cones are known to respond to various...
15 KB (1,859 words) - 20:29, 16 September 2021
processes that look like "fingers" or "feet" and often propel cells or growth cones across surfaces. Virtually all eukaryotic cells form such processes upon...
25 KB (3,212 words) - 14:49, 7 September 2024
there must be an extremely high degree of accuracy in which cell the growth cone forms neural connections. Although the target cell selection must be...
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through development, where Tropomyosin 4 was initially localized to the growth cone of growing neurons, but in mature neurons it was relocated to the somatodendritic...
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Cellular neuroscience Compartmental neuron models Connectome Dogiel cell Growth cone List of animals by number of neurons List of neuroscience databases Neuronal...
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movement of the axons (and subsequently the Schwann cells) is guided by the growth cone, a filamentous projection of the axon that actively searches for neurotrophins...
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positions, outgrowth of axons from neurons and guidance of the motile growth cone through the embryo towards postsynaptic partners, the generation of synapses...
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also makes swimming possible filopodia, enabling movement of the axonal growth cone flagellar motility, a swimming-like motion (observed for example in spermatozoa...
14 KB (1,626 words) - 21:32, 11 September 2024
processes during embryonic development including the guidance of axon growth cones, formation of tissue boundaries, cell migration, and segmentation. Additionally...
21 KB (2,476 words) - 16:32, 25 April 2024
from the growth cone at the leading edge. In neurons deprived of filopodia by partial inhibition of actin filaments polymerization, growth cone extension...
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several major contributions to neuroanatomy. He discovered the axonal growth cone, and demonstrated experimentally that the relationship between nerve...
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H, Carroll RC, Bassell GJ (2006). "Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses"...
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C9orf72–SMCR8 (Smith-Magenis chromosome region 8) complex suppresses primary cilium growth as a RAB8A GAP (GTPase activating protein), establishing a link between...
30 KB (3,424 words) - 01:44, 27 June 2024
EphA and EphB receptors mediates growth cone collapse while reverse signaling via ephrin-A and ephrin-B induces growth cone survival. The ability of Eph/ephrin...
28 KB (3,454 words) - 00:06, 2 June 2024
volcanic bombs, are also a common product of cinder cone eruptions. The growth of a cinder cone may be divided into four stages. In the first stage,...
15 KB (1,788 words) - 21:41, 1 July 2024
Conifer (section Conditions for growth)
Conifers are a group of cone-bearing seed plants, a subset of gymnosperms. Scientifically, they make up the division Pinophyta (/pɪˈnɒfɪtə, ˈpaɪnoʊfaɪtə/)...
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of the peripheral nervous system (PNS). Integrins are present at the growth cone of damaged PNS neurons and attach to ligands in the ECM to promote axon...
36 KB (3,929 words) - 14:48, 30 May 2024