• Thumbnail for Growth cone
    A growth cone is a large actin-supported extension of a developing or regenerating neurite seeking its synaptic target. It is the growth cone that drives...
    15 KB (1,695 words) - 10:16, 4 January 2024
  • framework is that when a growth cone "senses" a guidance cue, the receptors activate various signaling molecules in the growth cone that eventually affect...
    33 KB (4,365 words) - 15:00, 15 June 2024
  • Thumbnail for Conifer cone
    are known as scales. The umbo of a conifer cone refers to the first year's growth of a seed scale on the cone, showing up as a protuberance at the end of...
    23 KB (2,728 words) - 22:19, 8 June 2024
  • Thumbnail for Axon
    network in a growth cone will promote its neurite to become the axon. Growing axons move through their environment via the growth cone, which is at the...
    58 KB (6,926 words) - 08:35, 7 August 2024
  • Thumbnail for Retinal ganglion cell
    receptor on growth cones of the RGC axon. This morphogen initially attracts RGC axons, but then, through an internal change in the growth cone of the RGC...
    29 KB (3,521 words) - 03:39, 17 June 2024
  • Thumbnail for Brain
    protoplasm called a growth cone, studded with chemical receptors. These receptors sense the local environment, causing the growth cone to be attracted or...
    132 KB (15,613 words) - 14:37, 4 September 2024
  • Look up cone or coning in Wiktionary, the free dictionary. A cone is a basic geometrical shape. Cone may also refer to: Cone (category theory) Cone (formal...
    4 KB (657 words) - 13:55, 6 August 2024
  • Thumbnail for Ephrin A5
    on growth cone spreading. Additionally, EphA receptors were shown to exert opposite effects on motor neuron growth cones by reducing growth cone size...
    10 KB (1,211 words) - 05:21, 18 October 2022
  • development and play important roles in axon formation from neurites and in growth cone guidance and collapse through their interactions with microtubules. Cleaved...
    21 KB (2,518 words) - 22:06, 10 December 2023
  • Thumbnail for Laminin
    presence of laminin-1 can influence how the growth cone responds to other cues. For example, growth cones are repelled by netrin when grown on laminin-111...
    31 KB (3,430 words) - 21:00, 5 September 2024
  • Thumbnail for Tropic cues involved in growth cone guidance
    The growth cone is a highly dynamic structure of the developing neuron, changing directionality in response to different secreted and contact-dependent...
    26 KB (3,128 words) - 08:14, 18 August 2023
  • Thumbnail for Nerve injury
    involved in growth and proliferation. Neurotrophic factors act through retrograde transport in neurons, in which they are taken up by the growth cone of the...
    34 KB (4,113 words) - 01:03, 12 July 2024
  • Thumbnail for Optic chiasm
    hedgehog (Shh) and Wnt. This navigation is mediated by the neuronal growth cone, a structure that responds to the cues by ligand-receptor signalling...
    15 KB (1,712 words) - 17:03, 3 July 2024
  • Thumbnail for Role of cell adhesions in neural development
    force provides a mechanism for the growth cone to respond to direction cue, thereby directing neuronal axons. Growth cones are known to respond to various...
    15 KB (1,859 words) - 20:29, 16 September 2021
  • processes that look like "fingers" or "feet" and often propel cells or growth cones across surfaces. Virtually all eukaryotic cells form such processes upon...
    25 KB (3,212 words) - 14:49, 7 September 2024
  • there must be an extremely high degree of accuracy in which cell the growth cone forms neural connections. Although the target cell selection must be...
    10 KB (1,223 words) - 21:42, 8 June 2024
  • Thumbnail for Tropomyosin
    through development, where Tropomyosin 4 was initially localized to the growth cone of growing neurons, but in mature neurons it was relocated to the somatodendritic...
    51 KB (6,192 words) - 22:52, 17 August 2024
  • Thumbnail for Neuron
    Cellular neuroscience Compartmental neuron models Connectome Dogiel cell Growth cone List of animals by number of neurons List of neuroscience databases Neuronal...
    79 KB (9,160 words) - 08:37, 7 August 2024
  • movement of the axons (and subsequently the Schwann cells) is guided by the growth cone, a filamentous projection of the axon that actively searches for neurotrophins...
    26 KB (3,488 words) - 05:24, 13 March 2024
  • Thumbnail for Nervous system
    positions, outgrowth of axons from neurons and guidance of the motile growth cone through the embryo towards postsynaptic partners, the generation of synapses...
    72 KB (9,263 words) - 07:08, 2 August 2024
  • Thumbnail for Motility
    also makes swimming possible filopodia, enabling movement of the axonal growth cone flagellar motility, a swimming-like motion (observed for example in spermatozoa...
    14 KB (1,626 words) - 21:32, 11 September 2024
  • Thumbnail for Ephrin
    processes during embryonic development including the guidance of axon growth cones, formation of tissue boundaries, cell migration, and segmentation. Additionally...
    21 KB (2,476 words) - 16:32, 25 April 2024
  • Thumbnail for Filopodia
    from the growth cone at the leading edge. In neurons deprived of filopodia by partial inhibition of actin filaments polymerization, growth cone extension...
    12 KB (1,172 words) - 14:14, 5 April 2024
  • Thumbnail for Santiago Ramón y Cajal
    several major contributions to neuroanatomy. He discovered the axonal growth cone, and demonstrated experimentally that the relationship between nerve...
    46 KB (5,156 words) - 20:28, 13 September 2024
  • Thumbnail for FMR1
    H, Carroll RC, Bassell GJ (2006). "Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses"...
    27 KB (3,455 words) - 12:19, 13 May 2024
  • Thumbnail for C9orf72
    C9orf72–SMCR8 (Smith-Magenis chromosome region 8) complex suppresses primary cilium growth as a RAB8A GAP (GTPase activating protein), establishing a link between...
    30 KB (3,424 words) - 01:44, 27 June 2024
  • Thumbnail for Ephrin receptor
    EphA and EphB receptors mediates growth cone collapse while reverse signaling via ephrin-A and ephrin-B induces growth cone survival. The ability of Eph/ephrin...
    28 KB (3,454 words) - 00:06, 2 June 2024
  • Thumbnail for Cinder cone
    volcanic bombs, are also a common product of cinder cone eruptions. The growth of a cinder cone may be divided into four stages. In the first stage,...
    15 KB (1,788 words) - 21:41, 1 July 2024
  • Thumbnail for Conifer
    Conifers are a group of cone-bearing seed plants, a subset of gymnosperms. Scientifically, they make up the division Pinophyta (/pɪˈnɒfɪtə, ˈpaɪnoʊfaɪtə/)...
    50 KB (5,817 words) - 02:28, 14 September 2024
  • Thumbnail for Integrin
    of the peripheral nervous system (PNS). Integrins are present at the growth cone of damaged PNS neurons and attach to ligands in the ECM to promote axon...
    36 KB (3,929 words) - 14:48, 30 May 2024