HLA-DQ8 (DQ8) is a human leukocyte antigen serotype within the HLA-DQ (DQ) serotype group. DQ8 is a split antigen of the DQ3 broad antigen. DQ8 is determined...

DQA1*typing, or DR serotyping. Current serotyping can resolve, in one step, DQ8. HLA typing in autoimmunity is being increasingly used as a tool in diagnosis...

to the β-chain. The currently used serotypes are HLA-DQ2, -DQ3, -DQ4, -DQ5, -DQ6, -DQ7, -DQ8, -DQ9. HLA-DQ1 is a weak reaction to the α-chain and was replaced...

DQ8 may refer to: Dragon Quest VIII, a 2004 role-playing game. HLA-DQ8, an HLA-DQ receptor serotype associated with coeliac disease. This disambiguation...

higher risk when they carry a particular human leukocyte antigen (HLA-DQ2, HLA-DQ8 and HLA-DR4). APS-II affects women to a greater degree than men. Signs...

ancestry, and is associated with the human leukocyte antigen (HLA) haplotype HLA-DQ2 or HLA-DQ8 along with coeliac disease and gluten sensitivity. Dermatitis...

have a different HLA distribution, in particular more HLA-DQ1, compared to most persons with celiac disease, who have HLA-DQ2 and HLA-DQ8. Coeliac disease...

the second strongest linkage to Type 1 diabetes, and when paired with HLA-DQ8 is the most abundant phenotype found in late onset, "Type1-Type2" diabetes...

HLA-A antigens can mediate apoptosis in autoimmune disease and HLA A*0201 in with the HLA-DQ8 haplotypes has been documented. The class I sites were found...

patients should be tested for the presence of HLA-DQ2/DQ8 genetic markers because a negative HLA-DQ2 and HLA-DQ8 result has a high negative predictive value...

typical HLA-DQ2 or HLA-DQ8 alleles (see below). The vast majority of people with coeliac have one of two types (out of seven) of the HLA-DQ protein. HLA-DQ...

form of 'split antigen' of the broad antigen group DQ3 which also contains DQ8 and DQ9. DQ7 is linked by haplotype to a number of DQA1 (DQ alpha chain)...

Within molecular and cell biology, HLA-DQ3 (DQ3) is a broad serotype category with split antigens HLA-DQ7, DQ8, and DQ9. Historically, originally recognized...

bonds. The LMW ones are similar to Gliadin. Individuals possessing the HLA-DQ8 class II antigen receptor gene may demonstrate increased reactivity to...

understood, though there have been recent studies that suggest linkage with HLA-DR3/DR4-DQ8. Further, it is believed to involve a combination of genetic and environmental...

who have positive IgA tTG antibodies or have the at-risk haplotypes DQ2 or DQ8.46 (...) Historically, a GFD was occasionally used in the management of multiple...

taxonomy), barley, and rye. The T-cells are defined by the ability to react to HLA-DQ8 and DQ2.5 restricted antigens and gliadin is one of the antigens. Gliadin...

designation for the haplotype HLA-A*02:01~C*05:01~B*4402, the class I portion, of an ancestral haplotype (A2~B44~DR4~DQ8). The full haplotype is (for relative...

HLA-DR1 (DR1) is a HLA-DR serotype that recognizes the DRB1*01 gene products. It has been observed to be common among centenarians. The serology for the...

[citation needed] HLA-B7 along with HLA-DQ8 increased risk for cervical cancer in Costa Rican and South Asian women A weak relationship between HLA-B7 and sarcoidosis...

Major histocompatibility complex, class II, DQ alpha 1, also known as HLA-DQA1, is a human gene present on short arm of chromosome 6 (6p21.3) and also...

of cases have the HLA-DQ2 allele, which is found in over 90% of people with coeliac disease. Absence of HLA-DQ2 (and the rarer HLA-DQ8) makes coeliac disease...

Major histocompatibility complex, class II, DQ beta 1, also known as HLA-DQB1, is a human gene and also denotes the genetic locus that contains this gene...

remaining patients carry HLA-DQ2.2 or HLA-DQ8. He and his coworkers demonstrated that celiac disease patients who express HLA-DQ2.5 have gluten-specific...

HLA-DR is an MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. The complex of HLA-DR (Human...

at the HLA-DQ locus that encode HLA-DQ2 and/or HLA-DQ8 serotype proteins. About 2–3% of individuals who inherit these HLA-DQ2 and/or HLA-DQ8 serotypes...

HLA-DR4 (DR4) is an HLA-DR serotype that recognizes the DRB1*04 gene products. The DR4 serogroup is large and has a number of moderate frequency alleles...

of zonulin. Zonulin regulates intestinal lining tight junctions. HLA-DQ2 and HLA-DQ8 gene-carriers are also more prone. A paper published by Finn E. Somnier...

DR5-DQ7/DR7-DQ2 cannot mediate T1D as successfully as DR4-DQ8 or DR3-DQ2 (X is not DR3-DQ2 or DR7-DQ2). HLA DR3-DQ2 is not spread evenly among humans. It has...

association on the HLA A1-B8-DR3-DQ2 haplotype, the association appears not to extend beyond the HLA-B locus. A recent study of DR3-DQ2/DR4-DQ8 phenotype found...