HMOX1 (heme oxygenase 1 gene) is a human gene that encodes for the enzyme heme oxygenase 1 (EC 1.14.99.3). Heme oxygenase (abbreviated HMOX or HO) mediates...
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signaling, immunomodulatory, and cryoprotective roles. HMOX1 is an essential enzyme. Human HMOX1-deficiency is rare, however several cases have been reported...
34 KB (3,774 words) - 05:36, 22 August 2024
the response to oxidative stress such as CAT, SOD1, SOD2, SOD3, NFE2L2, HMOX1, GST-M1 or GST-T1 supporting the association of elevated levels of reactive...
42 KB (4,410 words) - 12:31, 5 November 2024
HGNC:5003 Q9UGU5 7136 HMHB1 HGNC:29677 O97980 7137 HMMR HGNC:5012 O75330 7138 HMOX1 HGNC:5013 P09601 7139 HMOX2 HGNC:5014 P30519 7140 HMSD HGNC:23037 A8MTL9...
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induction of the expression of the stress-responsive heme oxygenase-1 (HMOX1) isoenzyme that catabolizes heme (see below). The reason why cells must...
42 KB (4,371 words) - 06:57, 29 September 2024
peroxides, including hydrogen peroxide and peroxynitrite. Heme oxygenase-1 (HMOX1, HO-1) is an enzyme that catalyzes the breakdown of heme into the antioxidant...
29 KB (3,402 words) - 07:08, 20 May 2024
to the lysosome for degradation. This gene is localized to 22q13.1, with HMOX1 and MCM5 distally and HMG2L1 proximally positioned. TOM1 has been shown...
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described. Other genes involved affected by this mutation are Keap1, Nrf2 and HMOX1. The diagnosis is made either by testing of the fumarate hydratase activity...
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isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 (this enzyme) belong to the heme oxygenase family. ENSG00000103415...
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and thereby to increase the expression of genes such as heme oxygenase-1 (HMOX1), which increases production of the anti-inflammatory gaseous signaling...
37 KB (4,356 words) - 12:28, 5 November 2024
Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy depends on HMOX1 (heme oxygenase 1)-mediated increase in intracellular calcium levels and...
13 KB (1,097 words) - 18:28, 23 April 2024
exhibits similarities to other known oxidative stress genes like NQO1 and HMOX1. When exposed to the same amount of hydrogen peroxide, both mouse embryo...
9 KB (1,163 words) - 23:24, 2 December 2023
transcription of numerous genes that for diverse antioxidant proteins such as HMOX1 which encodes the carbon monoxide-forming and anti-inflammatory protein...
23 KB (3,059 words) - 16:19, 5 November 2023
mechanism. Nfe2l1 knockout mice also exhibit down-regulation of Gpx1 and Hmox1, and Nfe2l1 (this gene)-deficient hepatocytes from liver-specific Nfe2l1...
29 KB (3,660 words) - 09:08, 23 July 2024