Hemojuvelin (HJV), also known as repulsive guidance molecule C (RGMc) or hemochromatosis type 2 protein (HFE2), is a membrane-bound and soluble protein...
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suggests a potential mechanism to generate the soluble forms of HJV/hemojuvelin (s-hemojuvelin) found in the blood of rodents and humans. The furin substrates...
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HJV may refer to: Home Guard (Denmark) (Hjemmeværnet) Hemojuvelin Highlands J virus This disambiguation page lists articles associated with the title...
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parent, for the HJV (aka HFE2) gene, which encodes the protein hemojuvelin. Hemojuvelin is responsible for the maintaining correct levels of the protein...
12 KB (1,259 words) - 07:38, 26 July 2023
The majority of juvenile hemochromatosis cases are due to mutations in hemojuvelin. Mutations in TMPRSS6 can cause anemia through dysregulation of hepcidin...
22 KB (2,393 words) - 07:42, 23 February 2024
involves mutations in genes coding for the iron regulatory proteins hemojuvelin, transferrin receptor-2 and ferroportin. Hereditary hemochromatosis is...
46 KB (4,693 words) - 10:36, 31 May 2024
suggests a potential mechanism to generate the soluble forms of HJV/hemojuvelin (s-hemojuvelin) found in the blood of rodents and humans. The two proprotein...
10 KB (1,249 words) - 06:57, 17 March 2024
HFE2 can refer to: Hemojuvelin HAMP This disambiguation page lists articles associated with the same title formed as a letter–number combination. If an...
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family (in vertebrates) composed of RGMa, RGMb, and RGMc (also called hemojuvelin). RGMa has been implicated to play an important role in the developing...
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hepcidin deficiency. The majority of cases are caused by mutations in the hemojuvelin gene (HJV or RGMc/repulsive guidance molecule c). The exceptions, people...
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disease juvenile hemochromatosis (JH), caused by mutations in either hemojuvelin (HJV) or hepcidin (HAMP). The exact mechanisms of most of the various...
46 KB (5,567 words) - 14:57, 26 April 2024
were homozygotic. The G320V mutation in the HJV gene, which produces hemojuvelin protein, is widely distributed in central Europe and Greece. The term...
69 KB (7,318 words) - 22:37, 9 July 2024
is a hereditary hemochromatosis caused by mutations of a gene called hemojuvelin. While the symptoms and outcomes for these two diseases are similar,...
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hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6". British Journal of Haematology. 147 (4): 571–581...
112 KB (12,093 words) - 19:24, 2 July 2024