• Thumbnail for Hepatitis C virus nonstructural protein 2
    Nonstructural protein 2 (NS2) is a viral protein found in the hepatitis C virus. It is also produced by influenza viruses, and is alternatively known...
    9 KB (1,152 words) - 00:49, 3 December 2023
  • Thumbnail for Hepatitis C virus
    viral particles. Structural proteins made by the hepatitis C virus include Core protein, E1 and E2; nonstructural proteins include NS2, NS3, NS4A, NS4B...
    54 KB (6,612 words) - 08:16, 2 November 2024
  • Thumbnail for Hepatitis C virus nonstructural protein 5A
    Nonstructural protein 5A (NS5A) is a zinc-binding and proline-rich hydrophilic phosphoprotein that plays a key role in Hepatitis C virus RNA replication...
    10 KB (1,179 words) - 06:28, 28 March 2024
  • Thumbnail for Hepatitis C virus nonstructural protein 5B
    Nonstructural protein 5B (NS5B) is a viral protein found in the hepatitis C virus (HCV). It is an RNA-dependent RNA polymerase, having the key function...
    5 KB (561 words) - 16:00, 30 March 2024
  • Thumbnail for Hepatitis B virus
    Hepatitis B virus (HBV) is a partially double-stranded DNA virus, a species of the genus Orthohepadnavirus and a member of the Hepadnaviridae family of...
    56 KB (6,823 words) - 22:54, 10 November 2024
  • GB virus C (GBV-C), formerly known as hepatitis G virus (HGV) and also known as human pegivirus – HPgV is a virus in the family Flaviviridae and a member...
    14 KB (1,726 words) - 00:46, 8 November 2023
  • hepatitis C vaccine, a vaccine capable of protecting against the hepatitis C virus (HCV), is not yet available. Although vaccines exist for hepatitis...
    8 KB (782 words) - 08:57, 5 January 2024
  • Thumbnail for Dengue virus
    codes for three structural proteins (capsid protein C, membrane protein M, envelope protein E) and seven nonstructural proteins (NS1, NS2a, NS2b, NS3, NS4a...
    60 KB (7,209 words) - 21:21, 13 November 2024
  • Thumbnail for Positive-strand RNA virus
    viruses include pathogens such as the Hepatitis C virus, West Nile virus, dengue virus, and the MERS, SARS, and SARS-CoV-2 coronaviruses, as well as less clinically...
    16 KB (1,790 words) - 23:36, 12 October 2024
  • Thumbnail for Viral protein
    and groups of viral proteins include structural proteins, nonstructural proteins, regulatory proteins, and accessory proteins. Viruses are non-living and...
    14 KB (1,673 words) - 01:24, 21 April 2024
  • Thumbnail for Rift Valley fever
    reservoirs for the virus. Although many components of the RVFV's RNA play an important role in the virus' pathology, the nonstructural protein encoded on the...
    30 KB (3,050 words) - 09:35, 11 October 2024
  • Thumbnail for Coronavirus
    Coronavirus (redirect from Corona virus)
    mouse hepatitis virus (MHV) that causes hepatitis in mice were discovered. It was not realized at the time that these three different viruses were related...
    96 KB (10,558 words) - 14:18, 18 November 2024
  • Thumbnail for Brome mosaic virus
    Rice, C. M.; Strauss, J. H.; Haseloff, J.; Zimmern, D. (1985). "Sindbis virus proteins nsP1 and nsP2 contain homology to nonstructural proteins from several...
    12 KB (1,607 words) - 19:41, 22 October 2022
  • Thumbnail for Chikungunya
    Liu WJ, Prow NA, Geertsema C, Ligtenberg M, Vanlandingham DL, et al. (October 2010). "Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated...
    65 KB (6,440 words) - 04:28, 14 November 2024
  • Thumbnail for Coronavirus spike protein
    the virus' nonstructural proteins). The evolution rate in the spike gene is higher than that observed in the genome overall. Analyses of SARS-CoV-2 genomes...
    75 KB (7,399 words) - 06:53, 9 November 2024
  • Thumbnail for SARS-CoV-2
    coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19, the respiratory illness responsible for the COVID-19 pandemic. The virus previously...
    122 KB (12,462 words) - 03:40, 15 August 2024
  • Thumbnail for Ebola
    Ebola (redirect from Ebola Virus)
    mRNAs, which are then translated into structural and nonstructural proteins. The most abundant protein produced is the nucleoprotein, whose concentration...
    194 KB (18,637 words) - 04:57, 17 November 2024
  • Thumbnail for Picornavirus
    Picornavirus (redirect from Picorna virus)
    play in virulence of the virus. The rest of the genome encodes structural proteins at the 5' end and nonstructural proteins at the 3' end in a single...
    32 KB (3,646 words) - 15:03, 14 September 2024
  • Thumbnail for Parvovirus B19
    Parvovirus B19 (redirect from B19 virus)
    most notable of these is the large nonstructural protein commonly referred to as NS1. NS1 is a multifunctional protein that has a role in binding and operating...
    36 KB (4,124 words) - 05:21, 11 November 2024
  • Thumbnail for Murine coronavirus
    Yokomori K, Lai MM (October 1991). "Mouse hepatitis virus S RNA sequence reveals that nonstructural proteins ns4 and ns5a are not essential for murine...
    34 KB (4,193 words) - 11:02, 18 June 2024
  • Thumbnail for HBx
    HBx (category Viral nonstructural proteins)
    transduction. Although Protein X is normally absent in the Avihepadnavirus, a vestigial version has been identified in the duck hepatitis virus genome. Although...
    14 KB (1,563 words) - 14:36, 3 December 2023
  • Thumbnail for Discovery and development of NS5A inhibitors
    Nonstructural protein 5A (NS5A) inhibitors are direct acting antiviral agents (DAAs) that target viral proteins, and their development was a culmination...
    50 KB (5,211 words) - 01:38, 14 November 2024
  • Thumbnail for Astrovirus
    astrovirus capsid protein does not have similar homology to other known viral proteins, but the closest would be hepatitis E virus. Astroviruses infect...
    41 KB (5,024 words) - 06:58, 27 July 2024
  • Thumbnail for Betacoronavirus
    pp1ab) preceding other elements. This polyprotein is cleaved into 16 nonstructural proteins (see UniProt annotation of SARS rep, P0C6X7). As of May 2013, GenBank...
    15 KB (1,479 words) - 01:17, 9 March 2024
  • Thumbnail for VAPA
    Goff SP (August 2004). "Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication". Proceedings...
    15 KB (1,892 words) - 01:11, 30 December 2023
  • Aichivirus A (redirect from Aichi virus)
    protein, leader peptide, is the first protein translated within the polypeptide, followed by the structural proteins, and then nonstructural proteins...
    26 KB (2,985 words) - 21:08, 28 April 2024
  • survival. For example, influenza A virus and West Nile virus (WNV) use their NS1 (nonstructural protein 1) proteins to block RIG-I ubiquitination by TRIM25...
    25 KB (3,011 words) - 17:07, 24 May 2024
  • Thumbnail for Boceprevir
    protease inhibitor used to treat hepatitis caused by hepatitis C virus (HCV) genotype 1. It binds to the HCV nonstructural protein 3 active site. It was initially...
    12 KB (1,167 words) - 17:43, 26 July 2024
  • pharmaceutical drug for the treatment of hepatitis C. It is a pan-genotypic inhibitor of HCV nonstructural protein 5A. In China, it is approved for use in...
    5 KB (166 words) - 08:10, 11 May 2024
  • Thumbnail for RNA interference
    (December 2012). "Small interfering RNA targeting the nonstructural gene 1 transcript inhibits influenza A virus replication in experimental mice". Nucleic Acid...
    140 KB (15,409 words) - 05:20, 20 November 2024