• Thumbnail for Hereditary nonpolyposis colorectal cancer
    Hereditary nonpolyposis colorectal cancer (HNPCC) is a hereditary predisposition to colon cancer. HNPCC includes (and was once synonymous with) Lynch syndrome...
    47 KB (4,902 words) - 21:19, 19 February 2024
  • Thumbnail for Colorectal polyp
    affected tissues. Hereditary nonpolyposis colorectal cancer (HNPCC, also known as Lynch syndrome) is a hereditary colorectal cancer syndrome. It is the...
    30 KB (2,858 words) - 07:50, 6 April 2024
  • Thumbnail for Colorectal cancer
    associated with higher rates of colorectal cancer. The most common of these is hereditary nonpolyposis colorectal cancer (HNPCC, or Lynch syndrome) which...
    145 KB (15,792 words) - 21:07, 28 June 2024
  • Thumbnail for Hereditary cancer syndrome
    polyposis, hereditary breast–ovarian cancer syndrome, hereditary diffuse gastric cancer (HDGC), Hereditary nonpolyposis colorectal cancer (Lynch syndrome)...
    51 KB (5,554 words) - 14:58, 10 April 2024
  • Thumbnail for Precancerous condition
    authorities also refer to hereditary genetic conditions which predispose to developing cancer, such as hereditary nonpolyposis colorectal cancer, as a precancerous...
    15 KB (1,344 words) - 23:16, 29 March 2024
  • Thumbnail for MLH1
    on chromosome 3. The gene is commonly associated with hereditary nonpolyposis colorectal cancer. Orthologs of human MLH1 have also been studied in other...
    28 KB (3,414 words) - 10:03, 27 March 2024
  • Thumbnail for MSH2
    with microsatellite instability and some cancers, especially with hereditary nonpolyposis colorectal cancer (HNPCC). At least 114 disease-causing mutations...
    35 KB (4,241 words) - 03:25, 27 June 2024
  • Thumbnail for Small intestine cancer
    Radiation exposure Hereditary gastrointestinal cancer syndromes: familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, Peutz–Jeghers...
    9 KB (1,045 words) - 11:01, 26 December 2023
  • adenomatous polyposis Hereditary breast and ovarian cancer Hereditary nonpolyposis colorectal cancer Li–Fraumeni syndrome Nevoid basal-cell carcinoma syndrome...
    60 KB (6,725 words) - 03:01, 13 July 2024
  • Thumbnail for MSH6
    MSH6 (section Cancer)
    repair. Defects in hMSH6 are associated with atypical hereditary nonpolyposis colorectal cancer not fulfilling the Amsterdam criteria for HNPCC. hMSH6...
    23 KB (2,942 words) - 20:15, 5 April 2024
  • Thumbnail for MSH3
    MSH3 (section Role in Cancer)
    and hMSH2 with hMSH6: examination of mutations found in hereditary nonpolyposis colorectal cancer". Mol Cell Biol. 18 (11): 6616–23. doi:10.1128/mcb.18...
    17 KB (2,080 words) - 15:35, 9 January 2024
  • Thumbnail for Fordyce spots
    oily skin types, with some rheumatic disorders, and in hereditary nonpolyposis colorectal cancer. In the latter, the most common site for Fordyce spots...
    10 KB (1,070 words) - 05:06, 24 April 2024
  • person gets such a cancer, it is often associated with hereditary syndromes like Peutz-Jegher's, hereditary nonpolyposis colorectal cancer, or familial adenomatous...
    25 KB (2,817 words) - 00:40, 18 June 2024
  • of colon cancer. The MSH2 gene and later the MLH1 gene (also by DFCI investigators) are linked to hereditary nonpolyposis colorectal cancer (HNPCC). 1996:...
    18 KB (1,895 words) - 00:57, 28 June 2024
  • (formerly Hereditary Nonpolyposis Colorectal Cancer, HNPCC), characterized by a greatly increased risk of colorectal and endometrial cancer, plus a moderately...
    20 KB (2,462 words) - 12:57, 25 May 2024
  • invasive adenocarcinomas. The most frequent mutations in Hereditary nonpolyposis colorectal cancer (HNPCC) are mutations in the MSH2 and MLH1 genes. These...
    23 KB (2,530 words) - 05:58, 17 June 2024
  • cell cancer syndrome Hereditary neuralgic amyotrophy Hereditary nonpolyposis colorectal cancer Hermansky–Pudlak syndrome Hero syndrome Heyde's syndrome...
    41 KB (4,052 words) - 14:58, 17 June 2024
  • which are likely to have Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC). The Amsterdam criteria arose as a result of a...
    6 KB (721 words) - 14:14, 27 October 2023
  • Thumbnail for Genetic disorder
    type 1, neurofibromatosis type 2, Marfan syndrome, hereditary nonpolyposis colorectal cancer, hereditary multiple exostoses (a highly penetrant autosomal...
    35 KB (3,579 words) - 09:44, 9 July 2024
  • Thumbnail for Mendelian traits in humans
    Haemophilia: 53  Hereditary breast–ovarian cancer syndrome[citation needed] Hereditary nonpolyposis colorectal cancer[citation needed] HFE hereditary haemochromatosis...
    11 KB (458 words) - 07:38, 31 July 2023
  • Thumbnail for Microsatellite instability
    Microsatellite instability (category Cancer)
    Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability". Journal of the National Cancer Institute. 96...
    21 KB (2,633 words) - 08:51, 11 December 2023
  • Thumbnail for Cancer
    BRCA2 with a more than 75% risk of breast cancer and ovarian cancer, and hereditary nonpolyposis colorectal cancer (HNPCC or Lynch syndrome), which is present...
    185 KB (19,996 words) - 02:40, 6 July 2024
  • Thumbnail for Medical diagnosis
    clinical case definitions, are: Amsterdam criteria for hereditary nonpolyposis colorectal cancer McDonald criteria for multiple sclerosis ACR criteria...
    29 KB (3,606 words) - 20:33, 1 May 2024
  • Thumbnail for Mismatch repair cancer syndrome
    observed in the condition known as Lynch syndrome or hereditary nonpolyposis colorectal cancer, while biallelic mutations are observed in CMMR-D. People...
    7 KB (622 words) - 01:36, 11 March 2023
  • Thumbnail for Ovarian cancer
    known as hereditary nonpolyposis colorectal cancer (also known as Lynch syndrome), which confers a higher risk for developing a number of cancers, including...
    196 KB (20,972 words) - 19:41, 10 July 2024
  • Thumbnail for Ureteral cancer
    ureteral cancer. HNPCC (hereditary nonpolyposis colorectal cancer), also known as lynch syndrome, leads to an increased risk of developing ureteral cancer, as...
    14 KB (1,708 words) - 19:30, 20 May 2024
  • Thumbnail for Anaplastic astrocytoma
    Anaplastic astrocytoma (category Cancer)
    suspected hereditary predisposition. The main hereditary predispositions are mainly neurofibromatosis type I, Li-Fraumeni syndrome, hereditary nonpolyposis colorectal...
    8 KB (822 words) - 22:55, 13 December 2023
  • (December 1996). "Prophylactic colectomy in patients with hereditary nonpolyposis colorectal cancer". Annals of Medicine. 28 (6): 479–482. doi:10.3109/07853899608999111...
    18 KB (2,104 words) - 01:11, 30 May 2024
  • Thumbnail for Sebaceous adenoma
    condition that predisposes individuals to cancer. It is also linked to hereditary nonpolyposis colorectal cancer (Lynch syndrome). It is not the same as...
    5 KB (359 words) - 00:13, 12 June 2024
  • Thumbnail for DNA repair
    repair to be less effective than normal. In particular, Hereditary nonpolyposis colorectal cancer (HNPCC) is strongly associated with specific mutations...
    128 KB (15,837 words) - 04:28, 8 July 2024