• Thumbnail for High-throughput screening
    High-throughput screening (HTS) is a method for scientific discovery especially used in drug discovery and relevant to the fields of biology, materials...
    34 KB (4,314 words) - 18:49, 13 November 2024
  • High-throughput may refer to: High-throughput computing, a computer science concept High-throughput screening, a bioinformatics concept High-throughput...
    411 bytes (69 words) - 16:03, 11 November 2021
  • Thumbnail for Virtual screening
    assigning a priority order. Grid computing High-throughput screening Docking (molecular) Retro screening Scoring functions ZINC database Gillet V (2013)...
    34 KB (4,029 words) - 11:57, 5 November 2024
  • picture or film High-throughput screening, a method for scientific experimentation especially used in drug discovery Mechanical screening, the practice...
    2 KB (288 words) - 21:54, 14 April 2023
  • was initially proposed for quality control and hit selection in high-throughput screening (HTS) and has become a statistical parameter measuring effect...
    26 KB (3,541 words) - 14:49, 3 December 2023
  • image analysis. Unlike high-content analysis, high-content screening implies a level of throughput which is why the term "screening" differentiates HCS from...
    17 KB (2,285 words) - 15:41, 17 September 2024
  • methods and technologies that have been developed for 3D screening, parallel high-throughput screening approaches to test isogenic pairs of oncogene related...
    63 KB (7,727 words) - 13:06, 29 June 2024
  • natural materials like in medicinal plants. This is also known as high throughput screening (HTS) and is how most drug discoveries are made today, many cancer...
    10 KB (1,359 words) - 03:25, 26 January 2023
  • measure of statistical effect size. It has been proposed for use in high-throughput screening (HTS), where it is also known as Z-prime, to judge whether the...
    9 KB (1,096 words) - 05:49, 19 December 2023
  • Thumbnail for Drug discovery
    quantities of purified proteins, it has become common practice to use high throughput screening of large compounds libraries against isolated biological targets...
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  • ratio. It may also refer to: Z-value, in ecology Z-factor, in high-throughput screening Altman Z-score, in financial analysis This disambiguation page...
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  • single-tube approach. In contrast to conventional screening procedures such as high-throughput screening, biochemical assays are not required for binder...
    42 KB (4,746 words) - 16:04, 11 November 2024
  • expensive over time, despite improvements in technology (such as high-throughput screening, biotechnology, combinatorial chemistry, and computational drug...
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  • hit to lead stage: Target validation (TV) → Assay development → High-throughput screening (HTS) → Hit to lead (H2L) → Lead optimization (LO) → Preclinical...
    9 KB (1,012 words) - 01:56, 9 December 2023
  • In high-throughput screening (HTS), one of the major goals is to select compounds (including small molecules, siRNAs, shRNA, genes, et al.) with a desired...
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  • Thumbnail for CompTox Chemicals Dashboard
    latest data generated from the EPA's Toxicity Forecaster (ToxCast) high-throughput screening program. The Chemicals Dashboard incorporates data from several...
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  • Thumbnail for Fluorescence polarization immunoassay
    direct interaction studies, the technique has been adopted by high-throughput screening (HTS) since the mid 1990s to help facilitate the drug discovery...
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  • AG, a leading bioengineering company and its proprietary ultra-high-throughput screening platform.[self-published source] On 6 June 2022, it was reported...
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  • Combinatorial Chemistry & High Throughput Screening is a peer-reviewed scientific journal that covers combinatorial chemistry. It was established in 1998...
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  • activity, given a known starting point found, for example, by high-throughput screening. PubChem a database of small molecules from the chemical and biological...
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  • the National Center for Biotechnology Information (NCBI). These high-throughput screening genomics data are derived from microarray or RNA-Seq experimental...
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  • Thumbnail for Microfluidics
    low volumes of fluids to achieve multiplexing, automation, and high-throughput screening. Microfluidics emerged in the beginning of the 1980s and is used...
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  • are useful as potential drugs or agrochemicals. This relies on high-throughput screening which is capable of assessing the output at sufficient scale....
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  • millimeters to a few square centimeters to achieve automation and high-throughput screening. LOCs can handle extremely small fluid volumes down to less than...
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  • Thumbnail for Drug design
    drug Types of drug screening include phenotypic screening, high-throughput screening, and virtual screening. Phenotypic screening is characterized by...
    44 KB (5,022 words) - 08:47, 12 October 2024
  • Thumbnail for Cell Painting
    The Cell Painting assay is a high-content, high-throughput imaging technique used to capture a wide array of cellular phenotypes in response to diverse...
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  • an enzyme's functional characteristics in different contexts. High-throughput screening has benefitted from ABPP, particularly in the area of competitive...
    63 KB (6,157 words) - 16:00, 30 March 2024
  • "Hts.") High-temperature superconductivity High-throughput satellite High-throughput screening, drug discovery method DNA sequencing#High-throughput sequencing...
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  • Thumbnail for Exscalate4Cov
    usually involves high-throughput screening (HTS). HTS enables the rapid identification of active compounds. For example, virtual screening can be used as...
    28 KB (2,554 words) - 23:50, 18 September 2024
  • is a collection of stored chemicals usually used ultimately in high-throughput screening or industrial manufacture. The chemical library can consist in...
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