Homocysteine (/ˌhoʊmoʊˈsɪstiːn/) or Hcy: is a non-proteinogenic α-amino acid. It is a homologue of the amino acid cysteine, differing by an additional...
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Homocysteine methylase may refer to: Homocysteine S-methyltransferase 5-methyltetrahydropteroyltriglutamate—homocysteine S-methyltransferase This set index...
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Homocysteine thiolactone (HTL) is an intramolecular thioester of homocysteine synthesized by methionyl-tRNA synthetase in an error-editing reaction that...
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regenerated by methylation or is salvaged by removing the adenine and the homocysteine, leaving the compound dihydroxypentandione to spontaneously convert into...
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characterized by an abnormally high level of total homocysteine (that is, including homocystine and homocysteine-cysteine disulfide) in the blood, conventionally...
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In the field of enzymology, a betaine-homocysteine S-methyltransferase also known as betaine-homocysteine methyltransferase (BHMT) is a zinc metallo-enzyme...
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The enzyme homocysteine desulfhydrase (EC 4.4.1.2) catalyzes the chemical reaction L-homocysteine + H2O = hydrogen sulfide + NH3 + 2-oxobutanoate (overall...
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S-Adenosyl-L-homocysteine (SAH) is the biosynthetic precursor to homocysteine. SAH is formed by the demethylation of S-adenosyl-L-methionine. Adenosylhomocysteinase...
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Methyl-B12 converts homocysteine, in a reaction catalyzed by homocysteine methyltransferase, to methionine. A defect in homocysteine methyltransferase or...
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of methionine from homocysteine in most individuals. In humans it is encoded by the MTR gene (5-methyltetrahydrofolate-homocysteine methyltransferase)...
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cystine-homocysteine, homocysteine in homocysteine-homocysteine) via disulfide bonds. Since as an equilibrium process the proportion of free homocysteine is...
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adenosylmethionine:homocysteine methyltransferase, homocysteine methylase, homocysteine methyltransferase, homocysteine transmethylase, L-homocysteine S-methyltransferase...
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Adenosylhomocysteinase (redirect from S-adenosyl-L-homocysteine hydrolase)
hydrolysis of S-adenosylhomocysteine to homocysteine and adenosine. S-adenosyl-L-homocysteine + H2O ⇌ L-homocysteine + adenosine AdoHcyase is a highly conserved...
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Ethionine (redirect from S-ethyl-l-homocysteine)
IUPAC name 2-Amino-4-ethylsulfanylbutyric acid Other names S-Ethyl-L-homocysteine Identifiers CAS Number 13073-35-3 Y 3D model (JSmol) Interactive image...
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has authorized the health claim that betaine "contributes to normal homocysteine metabolism." Trimethylglycine is an N-methylated amino acid. It is a...
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In enzymology, a 5-methyltetrahydropteroyltriglutamate—homocysteine S-methyltransferase (EC 2.1.1.14) is an enzyme that catalyzes the chemical reaction...
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remethylation of homocysteine in the methionine cycle, and result in raised homocysteine levels. There is much evidence linking elevated homocysteine concentrations...
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10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Natural variation in this gene is common...
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1) that use SAM as a substrate produce S-adenosyl homocysteine as a product. S-Adenosyl homocysteine is a strong negative regulator of nearly all SAM-dependent...
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level for DNA reproduction, the cysteine cycle and the regulation of homocysteine. It is also the form found in circulation and transported across membranes...
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Cystathionine beta synthase (redirect from L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming))
first step of the transsulfuration pathway, from homocysteine to cystathionine: L-serine + L-homocysteine ⇌ {\displaystyle \rightleftharpoons } L-cystathionine...
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thetin-homocysteine S-methyltransferase (EC 2.1.1.3) is an enzyme that catalyzes the chemical reaction dimethylsulfonioacetate + L-homocysteine ⇌ {\displaystyle...
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N-Formylmethionine (redirect from N-formyl(methyl)homocysteine)
2-Formylamino-4-methylsulfanyl-butyric acid; Formylmethionine; N-Formyl(methyl)homocysteine Identifiers CAS Number 4289-98-9 Y 3D model (JSmol) Interactive image...
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Adenosylhomocysteine nucleosidase (redirect from S-adenozil-L-homocysteine homocysteinylribohydrolase)
chemical reaction S-adenosyl-L-homocysteine + H2O ⇌ {\displaystyle \rightleftharpoons } S-(5-deoxy-D-ribos-5-yl)-L-homocysteine + adenine Thus, the two substrates...
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certain enzymes. Remethylation is a major step in the conversion of homocysteine to the essential amino acid methionine. The remethylation process involves...
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is a metabolic pathway involving the interconversion of cysteine and homocysteine through the intermediate cystathionine. Two transsulfurylation pathways...
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S-ribosylhomocysteine lyase (redirect from S-(5-deoxy-D-ribos-5-yl)-L-homocysteine L-homocysteine-lyase ((4S)-4,5-dihydroxypentan-2,3-dione-forming))
4.4.1.21) catalyzes the reaction S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = L-homocysteine + (4S)-4,5-dihydroxypentan-2,3-dione This enzyme belongs to...
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and hematopoietic cells. Increased homocysteine and methylmalonic acid in Vitamin B12 deficiency Increased homocysteine in folate deficiency Normal levels...
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hydroxocobalamine at 1 mg daily to be ineffective in reducing levels of homocysteine. In a trial on adult volunteers, this dose did not lead to a significant...
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blood levels of the amino acid homocysteine is associated with premature atherosclerosis; whether elevated homocysteine in the normal range is causal is...
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