• Thumbnail for Hydroxybenzotriazole
    Hydroxybenzotriazole (abbreviated HOBt) is an organic compound that is a derivative of benzotriazole. It is a white crystalline powder, which as a commercial...
    6 KB (469 words) - 20:17, 30 July 2024
  • formation of amides by means of DCC (dicyclohexylcarbodiimide) and 1-hydroxybenzotriazole (HOBT). This reaction generally takes place at room temperature....
    4 KB (360 words) - 06:10, 10 June 2024
  • Thumbnail for Tolyltriazole
    has better solubility in some organic solvents.[citation needed] Hydroxybenzotriazole Wikimedia Commons has media related to Benzotriazoles. Benzotriazole...
    3 KB (163 words) - 01:36, 25 April 2024
  • Thumbnail for PyBOP
    amines in the context of peptide synthesis. It can be prepared from 1-hydroxybenzotriazole and a chlorophosphonium reagent under basic conditions. It is a substitute...
    5 KB (265 words) - 16:19, 3 August 2024
  • Thumbnail for HCTU
    difficult couplings HCTU and related reagents containing the 6-chloro-1-hydroxybenzotriazole moiety can be prepared by reaction with TCFH under basic conditions...
    5 KB (440 words) - 19:17, 3 August 2024
  • Thumbnail for N-Hydroxysuccinimide
    Some alternatives to NHS are the water-soluble analog sulfo-NHS, hydroxybenzotriazole (HOBt), 1-hydroxy-7-azabenzotriazole (HOAt), and pentafluorophenol...
    5 KB (397 words) - 20:55, 19 December 2023
  • Thumbnail for Dichloromethane
    DMAP, react with DCM to form methylene bispyridinium dichlorides. Hydroxybenzotriazole and related reagents used in peptide coupling react with DCM in the...
    29 KB (2,592 words) - 14:25, 17 July 2024
  • Thumbnail for BOP reagent
    acids and amines in peptide synthesis. It can be prepared from 1-hydroxybenzotriazole and a chlorophosphonium reagent under basic conditions. This reagent...
    5 KB (323 words) - 16:01, 3 August 2024
  • Thumbnail for HBTU
    salts. HBTU activates carboxylic acids by forming a stabilized HOBt (Hydroxybenzotriazole) leaving group. The activated intermediate species attacked by the...
    8 KB (639 words) - 12:03, 1 August 2024
  • Thumbnail for Carbodiimide
    convert carboxylic acids to amides or esters. Additives, such as N-hydroxybenzotriazole or N-hydroxysuccinimide, are often added to increase yields and decrease...
    14 KB (1,599 words) - 12:14, 21 July 2024
  • Thumbnail for Active ester
    are often used in peptide synthesis, e.g., N-hydroxysuccinimide, hydroxybenzotriazole. Active esters of acrylic acid are precursors to polymers with reactive...
    3 KB (277 words) - 01:21, 7 February 2024
  • Signals, distress, ship UN 0507 1.4S Signals, smoke UN 0508 1.3C 1-Hydroxybenzotriazole, anhydrous, dry or wetted with less than 20% water, by mass UN 0509...
    2 KB (60 words) - 00:22, 28 February 2024
  • Weinreb–Nahm amides from carboxylic acids. Various carbodiimide-, hydroxybenzotriazole-, and triphenylphosphine-based couplings have been reported specifically...
    12 KB (1,295 words) - 17:55, 27 January 2024
  • Thumbnail for Peptide synthesis
    (ethyl cyano(hydroxyimino)acetate). Amidinium reagents incorporating hydroxybenzotriazole moieties can exist in an N-form (guanadinium) or an O-form (uronium)...
    54 KB (6,100 words) - 16:21, 3 August 2024
  • Thumbnail for Ethyl cyanohydroxyiminoacetate
    or ethyl acetate. Compared with the benzotriazole derivatives 1-hydroxybenzotriazole (HOBt) and 1-hydroxy-7-azabenzotriazole (HOAt) (which are widely...
    9 KB (898 words) - 18:07, 30 July 2024
  • packed with equipment, containing flammable liquids UN 3474 4.1 1-Hydroxybenzotriazole, anhydrous, wetted with not less than 20% water, by mass UN 3475...
    10 KB (108 words) - 16:50, 5 July 2024
  • Thumbnail for (2-Nitrophenyl)acetic acid
    using menthol, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDCl), hydroxybenzotriazole(HOBt) and N,N-iisopropylethylamine(DIPEA). A pattern of reducing...
    10 KB (755 words) - 19:28, 15 July 2024