Ineffective erythropoiesis is defined by the expansion of early-stage erythroid precursors driven by erythropoietin, accompanied by the apoptosis of late-stage...
4 KB (230 words) - 16:26, 3 August 2024
hemoglobin). The imbalance of alpha to beta globin chains leads to ineffective erythropoiesis, increased hemolysis, and deranged iron homeostasis. Patients...
57 KB (5,458 words) - 22:49, 19 September 2024
associated with distinctive facial features due to ineffective erythropoiesis. The ineffective erythropoiesis causes marrow hyperplasia or expansion and bony...
5 KB (378 words) - 15:34, 30 March 2024
Anemia (section Erythropoiesis-stimulating agents)
globin synthesis Congenital dyserythropoietic anemias, causing ineffective erythropoiesis Anemia of kidney failure (also causing stem cell dysfunction)...
85 KB (8,824 words) - 01:19, 26 October 2024
Roughly 20% comes from other heme sources, however, including ineffective erythropoiesis, and the breakdown of other heme-containing proteins, such as...
48 KB (5,109 words) - 02:51, 15 September 2024
β-globin genes, causing ineffective production of normal alpha- or beta-globin chains, which can lead to ineffective erythropoiesis, premature red blood...
67 KB (7,132 words) - 02:15, 19 October 2024
demonstrated an increase in the lifespan of their red cells, reversal of ineffective erythropoiesis and splenomegaly, and an increase in total hemoglobin levels....
23 KB (2,469 words) - 04:12, 28 October 2024
ISBN 9781420016840. Retrieved 1 April 2011. Rivella, S. (May 2009). "Ineffective erythropoiesis and thalassemias". Curr. Opin. Hematol. 16 (3): 187–94. doi:10...
70 KB (2,582 words) - 03:15, 16 December 2023
Overproduction can be due to the reabsorption of a haematoma and ineffective erythropoiesis leading to increased red blood cell destruction. Gilbert's syndrome...
24 KB (2,897 words) - 05:51, 21 July 2024
Franz (2019-10-22). "Oral ferroportin inhibitor ameliorates ineffective erythropoiesis in a model of β-thalassemia". The Journal of Clinical Investigation...
22 KB (1,987 words) - 13:04, 23 June 2024
unconjugated bilirubin is made (such as in massive hemolysis or ineffective erythropoiesis) or because too little is conjugated (Gilbert's disease or Crigler–Najjar...
4 KB (434 words) - 01:16, 11 November 2022
(September 1962). "Jaundice in thalassemia minor: a consequence of "ineffective erythropoiesis"". The New England Journal of Medicine. 267: 523–9. doi:10...
28 KB (3,023 words) - 17:23, 9 July 2024
(April 2014). "An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia". Nature Medicine. 20 (4): 398–407. doi:10.1038/nm...
23 KB (1,570 words) - 04:15, 29 August 2024
of the newborn, hereditary spherocytosis, sickle cell disease) ineffective erythropoiesis massive tissue necrosis or large hematomas decreased clearance...
12 KB (1,183 words) - 07:01, 29 September 2024
hemolysis of any cause, including intravascular hemolysis and ineffective erythropoiesis (hemolysis within the bone marrow) Multiple frequent blood transfusions...
46 KB (4,697 words) - 03:21, 19 October 2024
thalassemias. CDA is one of many types of anemia, characterized by ineffective erythropoiesis, and resulting from a decrease in the number of red blood cells...
16 KB (1,303 words) - 21:28, 6 September 2024
Volker H.; Brugnara, Carlo; Lodish, Harvey F. (2001-12-01). "Ineffective erythropoiesis in Stat5a−/−5b−/− mice due to decreased survival of early erythroblasts"...
5 KB (729 words) - 07:50, 11 October 2024
mice has been shown and involvement in inherited anemias with ineffective erythropoiesis, anemia of chronic kidney diseases and iron-refractory iron-deficiency...
11 KB (1,292 words) - 16:18, 29 March 2024
peroxidases, soluble guanylate cyclase, nitric oxide synthase) and ineffective erythropoiesis in bone marrow. In addition to being a source of carbon monoxide...
34 KB (3,774 words) - 05:36, 22 August 2024
thalassemias. CDA is one of many types of anemia, characterized by ineffective erythropoiesis, and resulting from a decrease in the number of red blood cells...
20 KB (1,900 words) - 07:59, 26 October 2024
abnormalities, hypoglycosylation of certain RBC membrane proteins, and ineffective erythropoiesis. Cartilage–hair hypoplasia is a metaphyseal chondrodysplasia that...
26 KB (2,327 words) - 21:39, 20 September 2024
peroxidases, soluble guanylate cyclase, nitric oxide synthase) and ineffective erythropoiesis in bone marrow. The enzymatic velocity and catalytic activity...
23 KB (2,580 words) - 18:51, 23 May 2024
autosomal dominant inherited red blood cell disorder characterized by ineffective erythropoiesis and hemolysis resulting in anemia. Circulating erythroblasts and...
3 KB (215 words) - 02:43, 6 November 2023
effective for patients with chronic kidney disease when combined with erythropoiesis stimulating agents. Recent studies of iron and its associated with red...
19 KB (2,169 words) - 12:22, 27 August 2024
in the bone marrow in a process called hematopoiesis, which includes erythropoiesis, the production of red blood cells; and myelopoiesis, the production...
60 KB (6,801 words) - 13:04, 12 October 2024
hormones increase bulk, strength, and oxygen-carrying red blood cells.: 3 Erythropoiesis-stimulating agents such as erythropoietin (EPO), darbepoetin (dEPO)...
20 KB (1,821 words) - 22:04, 12 September 2024
Allopurinolα Mesnaα Rasburicaseα Ferrous salt Folic acid Hydroxocobalamin Erythropoiesis-stimulating agents Enoxaparin Phytomenadione Desmopressinα Heparin sodiumα...
38 KB (2,574 words) - 03:03, 15 July 2024
used in the treatment of iron poisoning. Iron supplements encourage erythropoiesis to increase red blood cell (RBC) production and oxygen transportation...
27 KB (2,503 words) - 15:05, 19 September 2024
(ferrous salt + folic acid) Folic acid Hydroxocobalamin Complementary: Erythropoiesis-stimulating agentsα Dabigatran Enoxaparin Heparin sodium Phytomenadione...
67 KB (4,833 words) - 09:29, 27 October 2024
host erythrocytes, the increased erythrocyte destruction and ensuing erythropoiesis result in a predominantly younger erythrocyte population, which in turn...
250 KB (25,861 words) - 02:25, 28 October 2024