Ineffective erythropoiesis is defined by the expansion of early-stage erythroid precursors driven by erythropoietin, accompanied by the apoptosis of late-stage...

hemoglobin). The imbalance of alpha to beta globin chains leads to ineffective erythropoiesis, increased hemolysis, and deranged iron homeostasis. Patients...

associated with distinctive facial features due to ineffective erythropoiesis. The ineffective erythropoiesis causes marrow hyperplasia or expansion and bony...

globin synthesis Congenital dyserythropoietic anemias, causing ineffective erythropoiesis Anemia of kidney failure (also causing stem cell dysfunction)...

Roughly 20% comes from other heme sources, however, including ineffective erythropoiesis, and the breakdown of other heme-containing proteins, such as...

β-globin genes, causing ineffective production of normal alpha- or beta-globin chains, which can lead to ineffective erythropoiesis, premature red blood...

demonstrated an increase in the lifespan of their red cells, reversal of ineffective erythropoiesis and splenomegaly, and an increase in total hemoglobin levels....

ISBN 9781420016840. Retrieved 1 April 2011. Rivella, S. (May 2009). "Ineffective erythropoiesis and thalassemias". Curr. Opin. Hematol. 16 (3): 187–94. doi:10...

Overproduction can be due to the reabsorption of a haematoma and ineffective erythropoiesis leading to increased red blood cell destruction. Gilbert's syndrome...

Franz (2019-10-22). "Oral ferroportin inhibitor ameliorates ineffective erythropoiesis in a model of β-thalassemia". The Journal of Clinical Investigation...

unconjugated bilirubin is made (such as in massive hemolysis or ineffective erythropoiesis) or because too little is conjugated (Gilbert's disease or Crigler–Najjar...

(September 1962). "Jaundice in thalassemia minor: a consequence of "ineffective erythropoiesis"". The New England Journal of Medicine. 267: 523–9. doi:10...

(April 2014). "An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia". Nature Medicine. 20 (4): 398–407. doi:10.1038/nm...

of the newborn, hereditary spherocytosis, sickle cell disease) ineffective erythropoiesis massive tissue necrosis or large hematomas decreased clearance...

hemolysis of any cause, including intravascular hemolysis and ineffective erythropoiesis (hemolysis within the bone marrow) Multiple frequent blood transfusions...

thalassemias. CDA is one of many types of anemia, characterized by ineffective erythropoiesis, and resulting from a decrease in the number of red blood cells...

Volker H.; Brugnara, Carlo; Lodish, Harvey F. (2001-12-01). "Ineffective erythropoiesis in Stat5a−/−5b−/− mice due to decreased survival of early erythroblasts"...

mice has been shown and involvement in inherited anemias with ineffective erythropoiesis, anemia of chronic kidney diseases and iron-refractory iron-deficiency...

peroxidases, soluble guanylate cyclase, nitric oxide synthase) and ineffective erythropoiesis in bone marrow. In addition to being a source of carbon monoxide...

thalassemias. CDA is one of many types of anemia, characterized by ineffective erythropoiesis, and resulting from a decrease in the number of red blood cells...

abnormalities, hypoglycosylation of certain RBC membrane proteins, and ineffective erythropoiesis. Cartilage–hair hypoplasia is a metaphyseal chondrodysplasia that...

peroxidases, soluble guanylate cyclase, nitric oxide synthase) and ineffective erythropoiesis in bone marrow. The enzymatic velocity and catalytic activity...

autosomal dominant inherited red blood cell disorder characterized by ineffective erythropoiesis and hemolysis resulting in anemia. Circulating erythroblasts and...

effective for patients with chronic kidney disease when combined with erythropoiesis stimulating agents. Recent studies of iron and its associated with red...

in the bone marrow in a process called hematopoiesis, which includes erythropoiesis, the production of red blood cells; and myelopoiesis, the production...

hormones increase bulk, strength, and oxygen-carrying red blood cells.: 3  Erythropoiesis-stimulating agents such as erythropoietin (EPO), darbepoetin (dEPO)...

Allopurinolα Mesnaα Rasburicaseα Ferrous salt Folic acid Hydroxocobalamin Erythropoiesis-stimulating agents Enoxaparin Phytomenadione Desmopressinα Heparin sodiumα...

used in the treatment of iron poisoning. Iron supplements encourage erythropoiesis to increase red blood cell (RBC) production and oxygen transportation...

(ferrous salt + folic acid) Folic acid Hydroxocobalamin Complementary: Erythropoiesis-stimulating agentsα Dabigatran Enoxaparin Heparin sodium Phytomenadione...

host erythrocytes, the increased erythrocyte destruction and ensuing erythropoiesis result in a predominantly younger erythrocyte population, which in turn...