• Thumbnail for Insulin-like growth factor
    The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
    14 KB (1,689 words) - 01:31, 19 August 2024
  • Thumbnail for Insulin-like growth factor 1
    Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role...
    35 KB (4,573 words) - 09:59, 28 August 2024
  • Thumbnail for Insulin-like growth factor 2
    Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin. The MeSH definition reads: "A well-characterized...
    15 KB (1,947 words) - 19:01, 2 October 2024
  • Thumbnail for Insulin-like growth factor-binding protein
    The insulin-like growth factor-binding protein (IGFBP) serves as a transport protein for insulin-like growth factor 1 (IGF-1). Approximately 98% of IGF-1...
    4 KB (468 words) - 09:09, 29 January 2023
  • Thumbnail for IGFBP3
    Insulin-like growth factor-binding protein 3, also known as IGFBP-3, is a protein that in humans is encoded by the IGFBP3 gene. IGFBP-3 is one of six...
    39 KB (4,717 words) - 13:09, 2 June 2024
  • Thumbnail for Insulin-like growth factor 1 receptor
    The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by...
    29 KB (3,603 words) - 16:26, 25 May 2024
  • Thumbnail for IGFBP1
    Insulin-like growth factor-binding protein 1 (IBP-1) also known as placental protein 12 (PP12) is a protein that in humans is encoded by the IGFBP1 gene...
    8 KB (1,045 words) - 09:28, 13 August 2023
  • growth factor 2 receptor (IGF-2R) Insulin-like growth factor Insulin-like growth factor 1 Insulin-like growth factor 2 Insulin-like growth factor-binding protein...
    608 bytes (51 words) - 12:36, 21 February 2022
  • Thumbnail for IGFBP7
    Insulin-like growth factor-binding protein 7 is a protein that in humans is encoded by the IGFBP7 gene. The major function of the protein is the regulation...
    19 KB (2,499 words) - 23:36, 23 December 2023
  • Thumbnail for Heparin-binding EGF-like growth factor
    Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. HB-EGF-like growth factor...
    20 KB (2,598 words) - 14:07, 21 July 2024
  • IGF-1 LR3 (category Insulin-like growth factor receptor agonists)
    as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in...
    5 KB (412 words) - 23:17, 19 June 2023
  • Thumbnail for Fibroblast growth factor 2
    (FGF2); Heparin-binding growth factor-2; and Endothelial cell growth factor-2. Gene sequencing revealed that this group is the same FGF2 protein and is a member...
    22 KB (2,698 words) - 17:05, 16 July 2024
  • Artemin Growth differentiation factor-9 (GDF9) Hepatocyte growth factor (HGF) Hepatoma-derived growth factor (HDGF) Insulin Insulin-like growth factors Insulin-like...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • known as pregnancy-associated plasma protein A, and insulin-like growth factor binding protein-4 protease is a protein encoded by the PAPPA gene in humans...
    5 KB (562 words) - 10:00, 27 March 2024
  • Thumbnail for Insulin-like growth factor 2 receptor
    Insulin-like growth factor 2 receptor (IGF2R), also called the cation-independent mannose-6-phosphate receptor (CI-MPR) is a protein that in humans is...
    13 KB (1,664 words) - 16:27, 25 May 2024
  • Thumbnail for Transferrin
    2001). "Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3". FEBS Letters. 509 (3):...
    24 KB (2,777 words) - 16:03, 10 July 2024
  • Thumbnail for Epidermal growth factor
    Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
    17 KB (1,708 words) - 13:56, 21 July 2024
  • Thumbnail for Insulin
    humans by the insulin (INS) gene. It is the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats, and protein by promoting...
    121 KB (13,799 words) - 18:31, 13 September 2024
  • Thumbnail for IGFALS
    Insulin-like growth factor binding protein, acid labile subunit, also known as IGFALS, is a protein which in humans is encoded by the IGFALS gene. The...
    9 KB (1,079 words) - 11:00, 21 February 2024
  • Thumbnail for Acanthosis nigricans
    particularly IGF-1. At high concentrations, insulin may also displace IGF-1 from insulin-like growth factor-binding protein (IGFBP). Increased circulating IGF...
    18 KB (1,782 words) - 19:54, 17 July 2024
  • Mecasermin (category Insulin-like growth factor receptor agonists)
    of mecasermin (rhIGF-1), insulin-like growth factor binding protein-3 (IGFBP-3), and insulin-like growth factor binding protein acid labile subunit (IGFALS)...
    5 KB (314 words) - 09:59, 19 August 2024
  • Thumbnail for Insulin receptor
    1997). "Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains". The Journal of Biological...
    31 KB (3,785 words) - 19:26, 2 September 2024
  • Frohman LA (March 2006). "Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing...
    12 KB (1,281 words) - 15:01, 22 July 2024
  • Thumbnail for Forkhead box protein O1
    serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter...
    28 KB (3,343 words) - 18:02, 7 November 2023
  • Androgen-binding protein Maltose-binding protein Phosphatidylethanolamine binding protein 1 Syntaxin binding protein 3 Insulin-like growth factor-binding protein...
    2 KB (263 words) - 21:49, 28 December 2020
  • Thumbnail for Laron syndrome
    growth hormone insensitivity or growth hormone receptor deficiency (GHRD), is an autosomal recessive disorder characterized by a lack of insulin-like...
    29 KB (2,885 words) - 06:45, 3 June 2024
  • Thumbnail for Sex hormone-binding globulin
    as a hepatokine. It decreases with high levels of insulin, growth hormone, insulin-like growth factor 1 (IGF-1), androgens, prolactin and transcortin....
    57 KB (4,584 words) - 22:43, 2 August 2024
  • A bone growth factor is a growth factor that stimulates the growth of bone tissue. Known bone growth factors include insulin-like growth factor-1 (IGF-1)...
    17 KB (2,024 words) - 16:54, 18 July 2024
  • Thumbnail for CTGF
    domains. These domains are, from N- to C-termini, the insulin-like growth factor binding protein (IGFBP) domain, the von Willebrand type C repeats (vWC)...
    13 KB (1,537 words) - 17:37, 27 December 2023
  • Growth hormone-binding protein (GHBP) is a soluble carrier protein for growth hormone (GH). The full range of functions of GHBP remains to be determined...
    23 KB (2,797 words) - 16:34, 5 October 2024