The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
14 KB (1,689 words) - 01:31, 19 August 2024
Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role...
35 KB (4,573 words) - 09:59, 28 August 2024
Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin. The MeSH definition reads: "A well-characterized...
15 KB (1,947 words) - 19:01, 2 October 2024
The insulin-like growth factor-binding protein (IGFBP) serves as a transport protein for insulin-like growth factor 1 (IGF-1). Approximately 98% of IGF-1...
4 KB (468 words) - 09:09, 29 January 2023
IGFBP3 (redirect from Insulin-like growth factor binding protein 3)
Insulin-like growth factor-binding protein 3, also known as IGFBP-3, is a protein that in humans is encoded by the IGFBP3 gene. IGFBP-3 is one of six...
39 KB (4,717 words) - 13:09, 2 June 2024
The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by...
29 KB (3,603 words) - 16:26, 25 May 2024
IGFBP1 (redirect from Insulin-like growth factor binding protein 1)
Insulin-like growth factor-binding protein 1 (IBP-1) also known as placental protein 12 (PP12) is a protein that in humans is encoded by the IGFBP1 gene...
8 KB (1,045 words) - 09:28, 13 August 2023
growth factor 2 receptor (IGF-2R) Insulin-like growth factor Insulin-like growth factor 1 Insulin-like growth factor 2 Insulin-like growth factor-binding protein...
608 bytes (51 words) - 12:36, 21 February 2022
IGFBP7 (redirect from Insulin-like growth-factor binding protein 7)
Insulin-like growth factor-binding protein 7 is a protein that in humans is encoded by the IGFBP7 gene. The major function of the protein is the regulation...
19 KB (2,499 words) - 23:36, 23 December 2023
Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. HB-EGF-like growth factor...
20 KB (2,598 words) - 14:07, 21 July 2024
IGF-1 LR3 (category Insulin-like growth factor receptor agonists)
as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in...
5 KB (412 words) - 23:17, 19 June 2023
(FGF2); Heparin-binding growth factor-2; and Endothelial cell growth factor-2. Gene sequencing revealed that this group is the same FGF2 protein and is a member...
22 KB (2,698 words) - 17:05, 16 July 2024
Artemin Growth differentiation factor-9 (GDF9) Hepatocyte growth factor (HGF) Hepatoma-derived growth factor (HDGF) Insulin Insulin-like growth factors Insulin-like...
10 KB (1,131 words) - 19:14, 31 March 2024
Pappalysin-1 (redirect from Insulin-like growth factor binding protein-4 protease)
known as pregnancy-associated plasma protein A, and insulin-like growth factor binding protein-4 protease is a protein encoded by the PAPPA gene in humans...
5 KB (562 words) - 10:00, 27 March 2024
Insulin-like growth factor 2 receptor (IGF2R), also called the cation-independent mannose-6-phosphate receptor (CI-MPR) is a protein that in humans is...
13 KB (1,664 words) - 16:27, 25 May 2024
Transferrin (redirect from Transferrin-binding proteins)
2001). "Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3". FEBS Letters. 509 (3):...
24 KB (2,777 words) - 16:03, 10 July 2024
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
17 KB (1,708 words) - 13:56, 21 July 2024
humans by the insulin (INS) gene. It is the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats, and protein by promoting...
121 KB (13,799 words) - 18:31, 13 September 2024
IGFALS (redirect from Insulin-like growth factor binding protein acid labile subunit)
Insulin-like growth factor binding protein, acid labile subunit, also known as IGFALS, is a protein which in humans is encoded by the IGFALS gene. The...
9 KB (1,079 words) - 11:00, 21 February 2024
Acanthosis nigricans (redirect from Acanthosis nigricans associated with obesity, insulin-resistant states, and endocrinopathy)
particularly IGF-1. At high concentrations, insulin may also displace IGF-1 from insulin-like growth factor-binding protein (IGFBP). Increased circulating IGF...
18 KB (1,782 words) - 19:54, 17 July 2024
Mecasermin (category Insulin-like growth factor receptor agonists)
of mecasermin (rhIGF-1), insulin-like growth factor binding protein-3 (IGFBP-3), and insulin-like growth factor binding protein acid labile subunit (IGFALS)...
5 KB (314 words) - 09:59, 19 August 2024
1997). "Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains". The Journal of Biological...
31 KB (3,785 words) - 19:26, 2 September 2024
Frohman LA (March 2006). "Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing...
12 KB (1,281 words) - 15:01, 22 July 2024
serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter...
28 KB (3,343 words) - 18:02, 7 November 2023
Androgen-binding protein Maltose-binding protein Phosphatidylethanolamine binding protein 1 Syntaxin binding protein 3 Insulin-like growth factor-binding protein...
2 KB (263 words) - 21:49, 28 December 2020
Laron syndrome (redirect from Severe primary insulin-like growth factor-1 deficiency)
growth hormone insensitivity or growth hormone receptor deficiency (GHRD), is an autosomal recessive disorder characterized by a lack of insulin-like...
29 KB (2,885 words) - 06:45, 3 June 2024
as a hepatokine. It decreases with high levels of insulin, growth hormone, insulin-like growth factor 1 (IGF-1), androgens, prolactin and transcortin....
57 KB (4,584 words) - 22:43, 2 August 2024
A bone growth factor is a growth factor that stimulates the growth of bone tissue. Known bone growth factors include insulin-like growth factor-1 (IGF-1)...
17 KB (2,024 words) - 16:54, 18 July 2024
CTGF (redirect from Connective tissue growth factor)
domains. These domains are, from N- to C-termini, the insulin-like growth factor binding protein (IGFBP) domain, the von Willebrand type C repeats (vWC)...
13 KB (1,537 words) - 17:37, 27 December 2023
Growth hormone-binding protein (GHBP) is a soluble carrier protein for growth hormone (GH). The full range of functions of GHBP remains to be determined...
23 KB (2,797 words) - 16:34, 5 October 2024