Interleukin-22 receptor is a type II cytokine receptor. It binds to Interleukin-22. It is a heterodimer of α1 and IL-10Rβ2 subunits. Xie MH, Aggarwal S...
1 KB (95 words) - 12:24, 14 April 2020
and resultant Thromboxane receptor activation to cause vascular endothelial and cardiac dysfunctions in mice. Interleukin 10 knockout frail mice develop...
40 KB (4,619 words) - 06:54, 7 November 2024
Interleukin 6 receptor (IL6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. Interleukin 6 (IL6) is a potent pleiotropic...
11 KB (1,438 words) - 14:27, 22 December 2023
Interleukin-22 (IL-22) is a protein that in humans is encoded by the IL22 gene. IL-22 is an α-helical cytokine. IL-22 binds to a heterodimeric cell surface...
17 KB (1,945 words) - 13:34, 9 July 2024
The interleukin-7 receptor is a protein found on the surface of cells. It is made up of two different smaller protein chains - i.e. it is a heterodimer...
6 KB (550 words) - 00:43, 19 August 2023
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the...
63 KB (7,473 words) - 05:58, 16 October 2024
Interleukin-1 receptor (IL-1R) is a cytokine receptor which binds interleukin 1. Two forms of the receptor exist. The type I receptor is primarily responsible...
3 KB (244 words) - 17:53, 24 January 2023
The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. IL-1RA was initially called the IL-1 inhibitor...
12 KB (1,323 words) - 14:55, 7 September 2024
The interleukin-3 receptor (CD123) is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune...
2 KB (206 words) - 15:30, 8 September 2024
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of an IL-12B (IL-12p40) subunit (which is shared with IL-12) and an IL-23A (IL-23p19) subunit...
20 KB (2,186 words) - 01:58, 3 November 2024
receptor Interleukin-4 receptor Interleukin-5 receptor Interleukin-6 receptor Interleukin-7 receptor Interleukin-9 receptor Interleukin-11 receptor Interleukin-12...
3 KB (248 words) - 11:20, 8 June 2024
The interleukin 4 receptor is a type I cytokine receptor. It is a heterodimer, that is, composed of two subunits. IL4R is the human gene coding for IL-4Rα...
7 KB (781 words) - 08:35, 20 August 2024
differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in...
45 KB (4,194 words) - 12:36, 2 May 2024
Interleukin-15 receptor is a type I cytokine receptor, binding interleukin-15. The IL-15 receptor is composed of the IL-2Rβ and γc subunits, along with...
7 KB (690 words) - 06:50, 29 April 2024
receptor interferon-gamma receptor Interferon type III receptor Interleukin-10 receptor Interleukin-20 receptor Interleukin-22 receptor Interleukin-28...
6 KB (616 words) - 18:29, 7 June 2023
Interleukin 21 receptor is a type I cytokine receptor. IL21R is its human gene. The protein encoded by this gene is a cytokine receptor for interleukin...
10 KB (864 words) - 16:12, 28 October 2022
Interleukin-28 receptor is a type II cytokine receptor found largely in epithelial cells. It binds type 3 interferons, interleukin-28 A (Interferon lambda...
10 KB (1,126 words) - 20:57, 24 June 2021
interleukin-5 receptor is a type I cytokine receptor. It is a heterodimer of the interleukin 5 receptor alpha subunit and CSF2RB. The IL-5 receptor (IL-5R)...
7 KB (848 words) - 11:49, 13 January 2024
The interleukin-23 receptor is a type I cytokine receptor. It is encoded in human by the IL23R gene. In complex with the interleukin-12 receptor β1 subunit...
13 KB (1,589 words) - 02:42, 19 December 2023
Interleukin 12 receptor is a type I cytokine receptor, binding interleukin 12 and consisting of beta 1 and beta 2 subunits. Chua AO, Chizzonite R, Desai...
2 KB (156 words) - 06:26, 28 May 2024
Interleukin-17 receptor (IL-17R) is a cytokine receptor which belongs to new subfamily of receptors binding proinflammatory cytokine interleukin 17A, a...
21 KB (2,139 words) - 19:25, 2 April 2024
The interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds...
9 KB (934 words) - 16:50, 3 October 2024
structural similarity to Interleukin-2 (IL-2). Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and...
39 KB (4,458 words) - 06:59, 3 June 2024
Interleukin 8 receptor, beta is a chemokine receptor. IL8RB is also known as CXCR2, and CXCR2 is now the IUPHAR Committee on Receptor Nomenclature and...
12 KB (1,474 words) - 17:52, 26 November 2024
Interleukin 9 receptor (IL9R) also known as CD129 (Cluster of Differentiation 129) is a type I cytokine receptor. IL9R also denotes its human gene. The...
8 KB (1,118 words) - 09:22, 27 March 2022
Interleukin 1 receptor, type II (IL-1R2) also known as CD121b (Cluster of Differentiation 121b) is an interleukin receptor. IL1R2 also denotes its human...
11 KB (1,399 words) - 09:00, 2 November 2024
Interleukin-2 (IL-2) is an interleukin, which is a type of cytokine signaling molecule forming part of the immune system. It is a 15.5–16 kDa protein that...
43 KB (5,007 words) - 10:38, 22 December 2024
Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and...
26 KB (3,273 words) - 08:48, 14 October 2024
fibrosis. The receptor for interleukin-4 is known as the IL-4Rα. This receptor exists in 3 different complexes throughout the body. Type 1 receptors are composed...
19 KB (2,293 words) - 11:05, 8 March 2024
Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (Cluster of Differentiation 127) is a protein that in humans is encoded by the IL7R gene...
6 KB (840 words) - 23:23, 20 February 2024