Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene. In...
22 KB (2,691 words) - 01:32, 15 March 2024
two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1β precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase)...
26 KB (3,273 words) - 13:58, 26 August 2024
lymphocyte-produced cytokines that mediate immune responses. Interleukin 1 alpha and interleukin 1 beta (IL1 alpha and IL1 beta) are cytokines that participate in...
45 KB (4,194 words) - 12:36, 2 May 2024
inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory...
12 KB (1,315 words) - 19:57, 6 May 2024
targeted at interleukin-1 beta. It has no cross-reactivity with other members of the interleukin-1 family, including interleukin-1 alpha. Common side...
15 KB (1,264 words) - 06:00, 18 July 2024
IL1RL2 (redirect from Interleukin 1 receptor-like 2)
interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor...
4 KB (603 words) - 21:06, 3 March 2023
subunits of the cytokine Interleukin-23. Interleukin-23 (IL-23) is a heterodimeric cytokine composed of an Interleukin 23 alpha subunit and an IL-12p40...
11 KB (1,358 words) - 17:09, 6 September 2023
Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1), is a human gene. The protein encoded by this gene...
8 KB (1,056 words) - 17:36, 21 May 2024
to the interleukin-1 receptor family. This protein is a receptor for interleukin 1 alpha (IL1A), interleukin 1 beta (IL1B), and interleukin 1 receptor...
10 KB (1,262 words) - 03:39, 18 February 2024
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the...
63 KB (7,473 words) - 02:17, 23 July 2024
Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, helper T cells and human B-lymphoblastoid...
14 KB (1,578 words) - 14:00, 26 February 2024
Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans, interleukin 10 is...
40 KB (4,619 words) - 05:18, 22 August 2024
They, in turn, secrete factors (such as the pro-inflammatory cytokine interleukin 8) that help creating an inflammatory environment, ultimately favoring...
154 KB (16,267 words) - 04:51, 11 August 2024
The Interleukin-1 family (IL-1 family) is a group of 11 cytokines that plays a central role in the regulation of immune and inflammatory responses to infections...
49 KB (6,005 words) - 16:30, 10 June 2024
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5–16 kDa protein that regulates the activities...
43 KB (5,000 words) - 13:28, 1 July 2024
Interleukin 5 (IL-5) is an interleukin produced by type-2 T helper cells and mast cells. Through binding to the interleukin-5 receptor, interleukin 5...
13 KB (1,523 words) - 19:27, 26 June 2024
1.4kb. It has a mass of 13 kDa and folds into 4 alpha helical bundles. The secondary structural features of IL-13 are similar to that of Interleukin 4...
24 KB (3,043 words) - 22:14, 16 June 2024
Xilonix) is a human monoclonal antibody of IgG1k isotype targeting Interleukin 1 alpha (IL1A). As of March 2017[update], bermekimab is in phase III clinical...
3 KB (196 words) - 01:45, 18 May 2024
As a signaling molecule, interleukin 11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation...
22 KB (2,510 words) - 04:11, 12 August 2024
Calcitonin (redirect from Calcitonin-related polypeptide alpha)
a molecular weight of 3454.93 daltons. Its structure comprises a single alpha helix. Alternative splicing of the gene coding for calcitonin produces a...
28 KB (3,084 words) - 05:10, 5 August 2024
inflammatory response including the release of pro-inflammatory interleukin 1 alpha, interleukin 1 beta, cytokines, kinins, lipid inflammatory mediators, complement...
8 KB (821 words) - 08:31, 9 October 2023
Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene. The IL-15 receptor is...
9 KB (1,235 words) - 03:38, 24 December 2023
pro-inflammatory cytokines tumor necrosis factor-alpha, interleukin-1 beta, interleukin-6 and interleukin-8 in the pathogenesis of the otitis media with...
22 KB (2,786 words) - 02:02, 19 August 2024
The interleukin-3 receptor (CD123) is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune...
2 KB (206 words) - 07:38, 16 June 2022
IL2RA (redirect from Interleukin-2 receptor alpha chain)
The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2...
23 KB (2,548 words) - 17:16, 27 August 2024
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells...
19 KB (2,293 words) - 11:05, 8 March 2024
Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA also denotes...
12 KB (1,569 words) - 05:04, 1 January 2024
gonadotropin, early pregnancy factor, prostaglandin E2, interleukin-1 alpha, interleukin 6, interferon-alpha, leukemia inhibitory factor and colony-stimulating...
51 KB (5,914 words) - 21:10, 16 August 2024
Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (Cluster of Differentiation 127) is a protein that in humans is encoded by the IL7R gene...
6 KB (840 words) - 23:23, 20 February 2024
Interleukin 36 receptor antagonist (IL-36RA) is a member of the interleukin-36 family of cytokines. It was previously named Interleukin-1 family member...
12 KB (1,151 words) - 00:55, 29 March 2023