Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA also denotes...
12 KB (1,569 words) - 05:04, 1 January 2024
interleukin-5 receptor is a type I cytokine receptor. It is a heterodimer of the interleukin 5 receptor alpha subunit and CSF2RB. The IL-5 receptor (IL-5R)...
7 KB (848 words) - 11:49, 13 January 2024
IL-5. IL-5 has been shown to interact with interleukin 5 receptor alpha subunit. The IL-5 receptor is composed of an α and a βc chain. The α subunit is...
13 KB (1,523 words) - 19:27, 26 June 2024
Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. The protein is also known as IL-23p19. It is one of the two subunits...
11 KB (1,358 words) - 17:09, 6 September 2023
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of an IL-12B (IL-12p40) subunit (which is shared with IL-12) and an IL-23A (IL-23p19) subunit...
20 KB (2,186 words) - 18:02, 17 October 2024
Interleukin-10 receptor subunit alpha is a subunit for the interleukin-10 receptor. IL10RA is its human gene. IL10RA has also been designated CDw210a (cluster...
11 KB (1,334 words) - 00:45, 3 October 2024
Interleukin 20 receptor, alpha subunit, is a subunit of the interleukin-20 receptor, the interleukin-26 receptor, and the interleukin-24 receptor. The...
12 KB (1,179 words) - 09:58, 31 August 2023
Interleukin 28 receptor, alpha subunit is a subunit for the interleukin-28 receptor. IL28RA is its human gene. The protein encoded by this gene belongs...
1 KB (169 words) - 02:07, 8 April 2022
with Interleukin 10 receptor, alpha subunit. The receptor complex for IL-10 also requires the IL10R2 chain to initiate signalling. This ligand–receptor combination...
40 KB (4,619 words) - 05:18, 22 August 2024
The interleukin 4 receptor is a type I cytokine receptor. It is a heterodimer, that is, composed of two subunits. IL4R is the human gene coding for IL-4Rα...
7 KB (781 words) - 08:35, 20 August 2024
Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kDa cytokine receptor like subunit encoded by this gene, and a 35 kDa subunit encoded...
10 KB (1,383 words) - 03:56, 13 August 2023
be regulated by MITF. The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein...
11 KB (1,438 words) - 14:27, 22 December 2023
Interleukin 11 receptor, alpha subunit is a subunit of the interleukin 11 receptor. IL11RA is its human gene. Interleukin 11 is a stromal cell-derived...
8 KB (1,049 words) - 07:02, 13 May 2024
chains, termed alpha (CD25), beta (CD122) and gamma (CD132). The gamma chain is shared by all family members. The IL-2 receptor (IL-2R) α subunit binds IL-2...
43 KB (5,000 words) - 12:13, 15 September 2024
Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene. The IL-15 receptor is...
9 KB (1,235 words) - 03:38, 24 December 2023
The interleukin-3 receptor (CD123) is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune...
2 KB (206 words) - 15:30, 8 September 2024
and consists of two subunits, interleukin-7 receptor-α (CD127) and common-γ chain receptor (CD132). The common-γ chain receptors is shared with various...
6 KB (550 words) - 00:43, 19 August 2023
structural similarity to Interleukin-2 (IL-2). Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and...
39 KB (4,458 words) - 06:59, 3 June 2024
multi-subunit receptor with IL-4. This receptor is a heterodimer receptor complex consisting of alpha IL-4 receptor (IL-4Rα) and alpha Interleukin-13 receptor...
24 KB (3,043 words) - 22:14, 16 June 2024
Interleukin 27 receptor, alpha is a subunit of the interleukin-27 receptor. IL27RA is its human gene. In mice, CD4+ helper T-cells differentiate into type...
5 KB (668 words) - 22:10, 29 September 2022
effects of interleukin 11. Interleukin 12 (IL-12) is a disulphide-bonded heterodimer consisting of a 35kDa alpha subunit and a 40kDa beta subunit. It is involved...
45 KB (4,194 words) - 12:36, 2 May 2024
Interleukin 10 receptor, beta subunit is a subunit for the interleukin-10 receptor. IL10RB is its human gene. IL10RB has also been designated CDw210b (cluster...
8 KB (964 words) - 23:46, 2 December 2023
responses. It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha. Interleukin 1 was discovered by Gery...
22 KB (2,679 words) - 06:27, 13 September 2024
The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. IL-1RA was initially called the IL-1 inhibitor...
12 KB (1,323 words) - 14:55, 7 September 2024
two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1β precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase)...
26 KB (3,273 words) - 08:48, 14 October 2024
The interleukin-23 receptor is a type I cytokine receptor. It is encoded in human by the IL23R gene. In complex with the interleukin-12 receptor β1 subunit...
13 KB (1,589 words) - 02:42, 19 December 2023
ciliary neurotrophic factor (CNTF) revisited. The interleukin-6 receptor can serve as an alpha-receptor for CTNF". The Journal of Biological Chemistry....
63 KB (7,473 words) - 05:58, 16 October 2024
Mepolizumab (category Anti-interleukin monoclonal antibodies)
Mepolizumab binds to IL-5 and prevents it from binding to its receptor, more specifically the interleukin 5 receptor alpha subunit, on the surface of eosinophil...
14 KB (1,147 words) - 07:33, 11 August 2024
Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (Cluster of Differentiation 127) is a protein that in humans is encoded by the IL7R gene...
6 KB (840 words) - 23:23, 20 February 2024
As a signaling molecule, interleukin 11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation...
22 KB (2,510 words) - 00:32, 20 October 2024