Elevated alkaline phosphatase (redirect from Reagan's isoenzyme)
unknown, isoenzyme studies using electrophoresis can confirm the source of the ALP. Heat stability also distinguishes bone and liver isoenzymes ("bone burns...
15 KB (1,662 words) - 21:45, 20 June 2024
Glycogen phosphorylase isoenzyme BB (abbreviation: GPBB) is an isoenzyme of glycogen phosphorylase. This isoform of the enzyme exists in cardiac (heart)...
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(brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different...
16 KB (1,765 words) - 20:23, 29 July 2024
(creatine kinase myocardial band), the bound combination of two variants (isoenzymes CKM and CKB) of the enzyme phosphocreatine kinase.[citation needed] In...
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early polyp/cancer. C. Tonus, M. Sellinger u. a.: Faecal pyruvate kinase isoenzyme type M2 for colorectal cancer screening: A meta-analysis. In: World Journal...
3 KB (347 words) - 21:35, 6 September 2023
Hexosaminidase (section Isoenzymes and genes)
Functional lysosomal β-hexosaminidase enzymes are dimeric in structure. Three isoenzymes are produced through the combination of α and β subunits to form any one...
16 KB (1,464 words) - 17:02, 27 September 2023
Aspartate transaminase (section Isoenzymes)
acid cycle. Two isoenzymes are present in a wide variety of eukaryotes. In humans:[citation needed] GOT1/cAST, the cytosolic isoenzyme derives mainly from...
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liver via the CYP3A4 isoenzyme of the cytochrome P450 enzyme system. Drugs that interfere with the activity of the CYP3A4 isoenzyme can increase serum dofetilide...
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undergoes extensive metabolism. It is biotransformed by CYP3A4 and CYP2B6 isoenzymes into norketamine, which, in turn, is converted by CYP2A6 and CYP2B6 into...
116 KB (11,202 words) - 23:02, 7 November 2024
epididymis and many organs, including the nervous system. There are three isoenzymes of 5α-reductase: steroid 5α-reductase 1, 2, and 3 (SRD5A1, SRD5A2 and...
37 KB (4,017 words) - 02:57, 2 November 2024
GABA-A receptors; (4) AMPA/kainate receptors; and (5) carbonic anhydrase isoenzymes. There is evidence that topiramate may alter the activity of its targets...
44 KB (3,871 words) - 18:24, 30 October 2024
because it has another valuable property: it allows the properties of isoenzymes catalysing the same reaction, but active in very different ranges of substrate...
47 KB (6,212 words) - 15:17, 28 October 2024
of CK isoenzymes had characteristic isoenzymes found within. Firstly, CK- MM was eluted, then CK-MB, followed by CK-BB. Therefore, the isoenzymes found...
54 KB (6,987 words) - 04:26, 19 October 2024
albumin and α1-glycoprotein. Fluoxetine is metabolized in the liver by isoenzymes of the cytochrome P450 system, including CYP2D6. The role of CYP2D6 in...
118 KB (11,819 words) - 01:14, 4 November 2024
Remedeine Forte). Dihydrocodeine is metabolised by the CYP450 system isoenzyme 2D6 to dihydromorphine, which mediates the majority of its analgesic effects...
3 KB (304 words) - 11:58, 26 January 2023
synthesized through addition of DOPAL and dopamine. CYP2D6, a cytochrome P450 isoenzyme is involved in two steps along the biosynthetic pathway, catalyzing both...
142 KB (13,823 words) - 14:44, 9 November 2024
orientalis s.l. Hybrid status not yet tested by genetic data; according to isoenzyme profiles a less-evolved, relict population of F. sylvatica or intermediate...
58 KB (5,203 words) - 22:22, 6 November 2024
inhibiting the activity of cyclooxygenase enzymes (the COX-1 and COX-2 isoenzymes). In cells, these enzymes are involved in the synthesis of key biological...
111 KB (11,570 words) - 12:10, 2 November 2024
Diagram of cytochrome P450 isoenzyme 2C9 with the haem group in the centre of the enzyme....
29 KB (2,971 words) - 18:21, 3 September 2024
glucokinase, though it is no more specific for glucose than the other mammalian isoenzymes. Genes that encode hexokinase have been discovered in every domain of...
15 KB (1,568 words) - 19:28, 22 June 2024
fifth human lysyl oxidase isoenzymes, and the consequences of a targeted inactivaton of the first described lysyl oxidase isoenzyme in mice (PDF). Oulu: Oulun...
49 KB (5,416 words) - 03:58, 20 September 2024
by rapid degradation of cortisol by 11β-hydroxysteroid dehydrogenase isoenzyme 2 (11β-HSD2) in mineralocorticoid target tissues. Mineralocorticoid effects...
54 KB (5,544 words) - 02:02, 8 October 2024
members of the Daucus genus were examined to determine differences in isoenzyme patterns and plastid DNA. The four were: Daucus carota subspecies sativus...
9 KB (913 words) - 21:19, 30 July 2024
and fast axonal, or axoplasmic transport. In sperm, a testis-specific isoenzyme GAPDHS is expressed. Under normal cellular conditions, cytoplasmic GAPDH...
33 KB (3,786 words) - 00:05, 30 July 2024
Lactate dehydrogenase (section Isoenzymes)
genes, respectively. These two subunits can form five possible tetramers (isoenzymes): LDH-1 (4H), LDH-5 (4M), and the three mixed tetramers (LDH-2/3H1M, LDH-3/2H2M...
42 KB (4,795 words) - 21:02, 11 June 2024
as diphenhydramine. Brompheniramine is metabolised by cytochrome P450 isoenzymes in the liver. Brompheniramine is part of a series of antihistamines including...
8 KB (511 words) - 15:46, 7 September 2024
cells based on elevated cardiac serum markers such as creatine kinase isoenzyme (CK)-MB and troponin T or troponin I, and thus have a diagnosis of non-ST...
14 KB (1,347 words) - 07:38, 31 August 2024
2017). "How fast monoamine oxidases decompose adrenaline? Kinetics of isoenzymes A and B evaluated by empirical valence bond simulation". Proteins. 85...
57 KB (6,576 words) - 08:23, 29 October 2024
tract, and has rapid first-pass hepatic metabolism; it is metabolized by isoenzymes of the cytochrome P450 system, including CYP3A4, CYP2D6, and, to a lesser...
30 KB (2,575 words) - 19:36, 30 October 2024