JQ1 is a thienotriazolodiazepine and a potent inhibitor of the BET family of bromodomain proteins which include BRD2, BRD3, BRD4, and the testis-specific...
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the University of Edinburgh. Adjudin CDD-2807 Dimethandrolone undecanoate JQ1 TDI-11861 "A non-hormonal pill could soon expand men's birth control options"...
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List of minor planets: 16001–17000 (redirect from (16684) 1994 JQ1)
May 3, 1994 San Marcello L. Tesi, G. Cattani · 11 km MPC · JPL 16684 1994 JQ1 — May 11, 1994 La Palma M. J. Irwin, A. Żytkow cubewano (cold) · critical...
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21491 1998 JL1 — May 1, 1998 Haleakala NEAT NYS 1.8 km MPC · JPL 21492 1998 JQ1 — May 1, 1998 Haleakala NEAT · 2.9 km MPC · JPL 21493 1998 JA2 — May 1,...
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with the pan-HDAC inhibitor LBH589 (panobinostat) and the BET bromodomain JQ1 compound. Trichostatin A (TSA) and others are being investigated as anti-inflammatory...
26 KB (2,974 words) - 05:26, 31 May 2024
motility, and it has been investigated as a potential male contraceptive drug. JQ1 TDI-11861 YCT529 Holdaway J, Georg GI (May 2024). "An emerging target for...
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2024-03-11. "Jetstar (JQ)#1 ✈ FlightAware". FlightAware. Retrieved 2024-03-19. "JQ1 schedule. (Jetstar Airways flight: Melbourne -> Honolulu)". info.flightmapper...
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GABAA receptor positive allosteric modulators include: Apafant Israpafant JQ1 Catabay, A.; Taniguchi, M.; Jinno, K.; Pesek, J. J.; Williamsen, E. (1 March...
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Shilatifard A, Roy AL (2014). "Regulation of MYC expression and differential JQ1 sensitivity in cancer cells". PLOS ONE. 9 (1): e87003. Bibcode:2014PLoSO...
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cells, preventing maturation. Male mice – injection of a solution of the JQ1 molecule to bind to a pocket of BRDT necessary for chromatin remodeling,...
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— May 3, 2002 Desert Eagle W. K. Y. Yeung · 2.5 km MPC · JPL 48291 2002 JQ1 — May 4, 2002 Desert Eagle W. K. Y. Yeung fast? 2.0 km MPC · JPL 48292 2002...
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36.8 56.7 BR-mag: 1.26; taxonomy: BR-IR catalog · MPC · JPL (16684) 1994 JQ1 1994 La Palma M. J. Irwin A. Żytkow 149 cubewano (cold) 44.1 0.05 4 41.8...
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Antoniazzi May 1, 1997 Bologna San Vittore Obs. · 3.1 km MPC · JPL 42594 1997 JQ1 — May 1, 1997 Caussols ODAS · 6.1 km MPC · JPL 42595 1997 PL — August 1...
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(8361) 1990 JN1 1 May 1990 list 15810 Arawn 12 May 1994 list (16684) 1994 JQ1 11 May 1994 list (48443) 1990 HY5 29 April 1990 list (58165) 1990 HQ5 29...
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demonstrated that FP-RMS subtypes were especially sensitive to inhibitors (such as JQ1) of a super enhancer bound protein BRD4. Embryonal RMS usually presents with...
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potentially lead to the development of future male contraceptive drugs. CDD-2807 JQ1 YCT529 Rossetti T, Ferreira J, Ghanem L, Buck H, Steegborn C, Myers RW, et al...
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2005 RN43 (145453) 2005 RR43 148780 Altjira (15807) 1994 GV9 (16684) 1994 JQ1 174567 Varda (19255) 1994 VK8 19521 Chaos (202421) 2005 UQ513 (24835) 1995...
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locations of Bio-JQ1 throughout the genome, as determined using Chem-seq, are almost identical to the ChIP-seq derived locations of the JQ1’s known target...
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mechanism of action requires more clarification. BRDT inhibitors such as JQ1 have been shown to produce reversible sterility in male mice by blocking...
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2001 HY31 28 April 2001 list (48290) 2002 JH 3 May 2002 list (48291) 2002 JQ1 4 May 2002 list (48297) 2002 LJ24 9 June 2002 list 50412 Ewen 26 February...
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1990 JN1 1 May 1990 list [A] 15810 Arawn 12 May 1994 list [A] (16684) 1994 JQ1 11 May 1994 list [A] (19299) 1996 SZ4 16 September 1996 list [B][C] (48443)...
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Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation". PLOS Pathogens. 11 (7): e1005066. doi:10.1371/journal...
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official cubewanos are 15760 Albion, (15807) 1994 GV9, and (16684) 1994 JQ1. "JPL Small-Body Database Browser: 19255 (1994 VK8)" (2000-11-27 last obs)...
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2003 HS55 — April 29, 2003 Socorro LINEAR NYS 1.6 km MPC · JPL 128008 2003 JQ1 — May 1, 2003 Socorro LINEAR EOS 4.7 km MPC · JPL 128009 2003 JP6 — May 1...
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inducers of Apolipoprotein A-I by both GSK and Resverlogix. In 2010 the use of JQ1, a tert-butyl synthetic precursor of OTX-015, was published having activity...
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super-enhancers are enriched in the target of the JQ1 small molecule, BRD4, so treatment with JQ1 causes exceptional losses in expression for super-enhancer—associated...
39 KB (4,359 words) - 19:36, 5 August 2024
2017-05-02). "IAU Minor Planet Center". "JPL Small-Body Database Browser: (2017 JQ1)" (last observation: 2017-05-03). "IAU Minor Planet Center". "JPL Small-Body...
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histone hyperacetylation in elongating spermatids. BET inhibitors such as JQ1 block the region of BRDT responsible for chromatin binding, and cause a reversible...
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important for leukemia, leading to a series of clinical trials with a new drug, JQ1. By studying cancer epigenetics, Vakoc has also identified a new subtype...
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bromodomain-specific functions of members of the BET family, small-molecule inhibitors JQ1 and I-BET were developed, but they lacked inter- and intra-BET (between BDs...
21 KB (2,510 words) - 19:34, 18 March 2024