• Thumbnail for KV1
    Tomb KV1, located in the Valley of the Kings in Egypt, was used for the burial of Pharaoh Ramesses VII of the Twentieth Dynasty. Although it has been...
    7 KB (789 words) - 21:29, 20 February 2024
  • Thumbnail for KCNA3
    KCNA3 (redirect from KV1.3)
    voltage-gated channel, shaker-related subfamily, member 3, also known as KCNA3 or Kv1.3, is a protein that in humans is encoded by the KCNA3 gene. Potassium channels...
    36 KB (4,367 words) - 22:37, 16 July 2024
  • Thumbnail for KCNA2
    Potassium voltage-gated channel subfamily A member 2 also known as Kv1.2 is a protein that in humans is encoded by the KCNA2 gene. Potassium channels...
    12 KB (1,518 words) - 22:32, 16 July 2024
  • Thumbnail for Kv1.1
    Potassium voltage-gated channel subfamily A member 1 also known as Kv1.1 is a shaker related voltage-gated potassium channel that in humans is encoded...
    16 KB (2,127 words) - 10:05, 16 September 2024
  • It targets voltage-gated potassium channels, primarily the subtypes Kv1.2 and Kv1.3. Ts15 can be isolated from the venom of Tityus serrulatus, otherwise...
    4 KB (515 words) - 20:01, 24 October 2021
  • Thumbnail for KCNA5
    voltage-gated channel, shaker-related subfamily, member 5, also known as KCNA5 or Kv1.5, is a protein that in humans is encoded by the KCNA5 gene. Potassium channels...
    12 KB (1,484 words) - 00:45, 17 July 2024
  • Thumbnail for KCNA4
    Potassium voltage-gated channel subfamily A member 4 also known as Kv1.4 is a protein that in humans is encoded by the KCNA4 gene. It contributes to the...
    15 KB (1,799 words) - 23:37, 16 July 2024
  • deployed by the Soviets in World War II KV1, the tomb of Pharaoh Ramesses VII in the Valley of the Kings, Egypt KV1, a variant of the Jackson King V electric...
    489 bytes (112 words) - 14:13, 4 October 2019
  • Thumbnail for Stichodactyla toxin
    potassium channels (KV1.6 > KV1.3 > KV1.1 = KV3.2 > Kv1.4, in decreasing potency) in the nanomolar to low micromolar range. KV1.3 is required for sustaining...
    75 KB (8,640 words) - 00:14, 23 December 2024
  • Thumbnail for KCNA7
    KCNA7 (redirect from Kv1.7)
    Potassium voltage-gated channel subfamily A member 7 also known as Kv1.7 is a protein that in humans is encoded by the KCNA7 gene. The protein encoded...
    3 KB (430 words) - 03:12, 17 April 2022
  • B, Kv1.2, and SK potassium channels. Pi4 binds to Shaker B potassium channels, the Drosophila homologue of the voltage-gated potassium channel Kv1.1....
    8 KB (886 words) - 19:58, 19 August 2021
  • Thumbnail for Voltage-gated potassium channel
    non-inactivating Kvα1.x - Shaker-related: Kv1.1 (KCNA1), Kv1.2 (KCNA2), Kv1.3 (KCNA3), Kv1.5 (KCNA5), Kv1.6 (KCNA6), Kv1.7 (KCNA7), Kv1.8 (KCNA10) Kvα2.x - Shab-related:...
    17 KB (1,772 words) - 00:46, 21 December 2024
  • BmP02 (section Kv1.3)
    Martensi Karsch (BmK) scorpion. The toxin acts on potassium channels, blocking Kv1.3 and slowing the deactivation of Kv4.2. BmP02 is not toxic to humans or...
    10 KB (1,328 words) - 22:50, 22 December 2024
  • Thumbnail for Twentieth Dynasty of Egypt
    discovery by Howard Carter in 1922. Ramesses VII's only monument is his tomb, KV1.[citation needed] Almost nothing is known about Ramesses VIII's reign, which...
    27 KB (2,714 words) - 11:45, 16 January 2025
  • Thumbnail for Hg1 (toxin)
    it selectively inhibits the potassium channel Kv1.3 and, with a lower affinity, channels Kv1.1 and Kv1.2. The Hg1 toxin is named after the Mexican scorpion...
    9 KB (571 words) - 11:11, 10 November 2024
  • the African emperor scorpion Pandinus imperator. Pi5 inhibits human Kv1.2 and Kv1.3 channels as well as Drosophila Shaker B potassium channels. Pi5 is...
    4 KB (501 words) - 18:46, 17 October 2024
  • Thumbnail for Clofazimine
    diabetes. Because the Kv1.3-high effector memory T cells (TEM) are actively involved in the development of these diseases, and Kv1.3 activity is essential...
    22 KB (1,987 words) - 15:09, 12 January 2025
  • BgK blocks the Kv1.1, Kv1.2, and Kv1.3 channels with similar affinities. IC50 is 6 nM for Kv1.1, 15 nM for Kv1.2, and 10 nM for Kv1.3. Meanwhile, tests...
    9 KB (1,111 words) - 23:00, 22 December 2024
  • Thumbnail for LmKTT-1a
    toxin, it both inhibits trypsin activity and blocks Kv1 channels with a weak selectivity towards Kv1.3 channels. The LmKTT-1a toxin was first identified...
    8 KB (829 words) - 00:30, 23 December 2024
  • encodes the voltage-gated potassium channel KV1.1, are responsible for this subtype of episodic ataxia. KV1.1 is expressed heavily in basket cells and...
    31 KB (3,132 words) - 06:50, 2 November 2024
  • but with dot inlays, no binding, and rosewood fretboard. KV1(Artist Signature Series) The KV1 is a Dave Mustaine signature model and is the first commercially-sold...
    12 KB (1,769 words) - 20:31, 16 January 2025
  • Thumbnail for Amitriptyline
    MA, Friederich P (May 2007). "Amitriptyline is a potent blocker of human Kv1.1 and Kv7.2/7.3 channels". Anesthesia and Analgesia. 104 (5): 1256–64, tables...
    92 KB (8,716 words) - 04:37, 17 January 2025
  • Thumbnail for XEN-D0101
    XEN-D0101 is a selective antagonist of the voltage-gated potassium channel Kv1.5. Atrial fibrillation is the main focus of Xention’s drug development, as...
    6 KB (470 words) - 12:32, 19 July 2024
  • Thumbnail for BrMT
    The disulfide-linked dimer of BrMT possesses inhibitory effects on the Kv1 and Kv4 families of voltage-gated potassium channels. BrMT was first isolated...
    6 KB (598 words) - 04:36, 23 November 2024
  • Thumbnail for Dave Mustaine
    meaning it had two of the longer fins from the RR). The reshaped Mustaine KV1 model had slightly shorter fins, Kahler bridge and Seymour Duncan TB-5 bridge...
    152 KB (14,415 words) - 14:56, 24 January 2025
  • inhibit both serine proteases and potassium channels (more specifically the Kv1.3 channel). Venom basic protease inhibitor IX, also named BF9, is derived...
    8 KB (882 words) - 16:45, 26 July 2024
  • Thumbnail for KCNA6
    Potassium voltage-gated channel subfamily A member 6 also known as Kv1.6 is a protein that in humans is encoded by the KCNA6 gene. The protein encoded...
    3 KB (414 words) - 13:28, 1 August 2023
  • voltage-gated potassium channel Kv1.1 with no effect on other tested potassium channels (Kv1.2, Kv1.3, Kv1.4, Kv1.5, Kv1.6, Shaker IR, Kv2.1, Kv3.1, Kv4...
    10 KB (1,136 words) - 00:23, 23 December 2024
  • Thumbnail for Cobatoxin
    These 3 families differ in structure. Cobatoxin 1 and 2 both block the Kv1.1 K+-channels in mice and the Shaker B K+ channels in insects, which are...
    4 KB (472 words) - 03:34, 29 December 2021
  • Thumbnail for KV2
    tomb of Ramesses IV, and is located low in the main valley, between KV7 and KV1. It has been open since antiquity and contains a large amount of graffiti...
    8 KB (810 words) - 18:56, 16 September 2024