Tomb KV1, located in the Valley of the Kings in Egypt, was used for the burial of Pharaoh Ramesses VII of the Twentieth Dynasty. Although it has been...
7 KB (789 words) - 21:29, 20 February 2024
KCNA2 (redirect from Kv1.2 potassium channel)
Potassium voltage-gated channel subfamily A member 2 also known as Kv1.2 is a protein that in humans is encoded by the KCNA2 gene. Potassium channels...
12 KB (1,518 words) - 22:32, 16 July 2024
Potassium voltage-gated channel subfamily A member 1 also known as Kv1.1 is a shaker related voltage-gated potassium channel that in humans is encoded...
16 KB (2,127 words) - 10:05, 16 September 2024
It targets voltage-gated potassium channels, primarily the subtypes Kv1.2 and Kv1.3. Ts15 can be isolated from the venom of Tityus serrulatus, otherwise...
4 KB (515 words) - 20:01, 24 October 2021
KCNA5 (redirect from Kv1.5 potassium channel)
voltage-gated channel, shaker-related subfamily, member 5, also known as KCNA5 or Kv1.5, is a protein that in humans is encoded by the KCNA5 gene. Potassium channels...
12 KB (1,484 words) - 00:45, 17 July 2024
KCNA4 (redirect from Kv1.4 potassium channel)
Potassium voltage-gated channel subfamily A member 4 also known as Kv1.4 is a protein that in humans is encoded by the KCNA4 gene. It contributes to the...
15 KB (1,799 words) - 23:37, 16 July 2024
deployed by the Soviets in World War II KV1, the tomb of Pharaoh Ramesses VII in the Valley of the Kings, Egypt KV1, a variant of the Jackson King V electric...
489 bytes (112 words) - 14:13, 4 October 2019
potassium channels (KV1.6 > KV1.3 > KV1.1 = KV3.2 > Kv1.4, in decreasing potency) in the nanomolar to low micromolar range. KV1.3 is required for sustaining...
75 KB (8,640 words) - 00:14, 23 December 2024
Pandinus imperator toxin (Pi4) (section Kv1.2 channel)
B, Kv1.2, and SK potassium channels. Pi4 binds to Shaker B potassium channels, the Drosophila homologue of the voltage-gated potassium channel Kv1.1....
8 KB (886 words) - 19:58, 19 August 2021
non-inactivating Kvα1.x - Shaker-related: Kv1.1 (KCNA1), Kv1.2 (KCNA2), Kv1.3 (KCNA3), Kv1.5 (KCNA5), Kv1.6 (KCNA6), Kv1.7 (KCNA7), Kv1.8 (KCNA10) Kvα2.x - Shab-related:...
17 KB (1,772 words) - 00:46, 21 December 2024
discovery by Howard Carter in 1922. Ramesses VII's only monument is his tomb, KV1.[citation needed] Almost nothing is known about Ramesses VIII's reign, which...
27 KB (2,714 words) - 11:45, 16 January 2025
it selectively inhibits the potassium channel Kv1.3 and, with a lower affinity, channels Kv1.1 and Kv1.2. The Hg1 toxin is named after the Mexican scorpion...
9 KB (571 words) - 11:11, 10 November 2024
Pi5 (section hKv1.2 and hKv 1.3 channels)
the African emperor scorpion Pandinus imperator. Pi5 inhibits human Kv1.2 and Kv1.3 channels as well as Drosophila Shaker B potassium channels. Pi5 is...
4 KB (501 words) - 18:46, 17 October 2024
diabetes. Because the Kv1.3-high effector memory T cells (TEM) are actively involved in the development of these diseases, and Kv1.3 activity is essential...
22 KB (1,987 words) - 15:09, 12 January 2025
BgK blocks the Kv1.1, Kv1.2, and Kv1.3 channels with similar affinities. IC50 is 6 nM for Kv1.1, 15 nM for Kv1.2, and 10 nM for Kv1.3. Meanwhile, tests...
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toxin, it both inhibits trypsin activity and blocks Kv1 channels with a weak selectivity towards Kv1.3 channels. The LmKTT-1a toxin was first identified...
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encodes the voltage-gated potassium channel KV1.1, are responsible for this subtype of episodic ataxia. KV1.1 is expressed heavily in basket cells and...
31 KB (3,132 words) - 06:50, 2 November 2024
but with dot inlays, no binding, and rosewood fretboard. KV1(Artist Signature Series) The KV1 is a Dave Mustaine signature model and is the first commercially-sold...
12 KB (1,769 words) - 20:31, 16 January 2025
MA, Friederich P (May 2007). "Amitriptyline is a potent blocker of human Kv1.1 and Kv7.2/7.3 channels". Anesthesia and Analgesia. 104 (5): 1256–64, tables...
92 KB (8,716 words) - 04:37, 17 January 2025
XEN-D0101 is a selective antagonist of the voltage-gated potassium channel Kv1.5. Atrial fibrillation is the main focus of Xention’s drug development, as...
6 KB (470 words) - 12:32, 19 July 2024
The disulfide-linked dimer of BrMT possesses inhibitory effects on the Kv1 and Kv4 families of voltage-gated potassium channels. BrMT was first isolated...
6 KB (598 words) - 04:36, 23 November 2024
meaning it had two of the longer fins from the RR). The reshaped Mustaine KV1 model had slightly shorter fins, Kahler bridge and Seymour Duncan TB-5 bridge...
152 KB (14,415 words) - 14:56, 24 January 2025
inhibit both serine proteases and potassium channels (more specifically the Kv1.3 channel). Venom basic protease inhibitor IX, also named BF9, is derived...
8 KB (882 words) - 16:45, 26 July 2024
KCNA6 (redirect from Kv1.6 potassium channel)
Potassium voltage-gated channel subfamily A member 6 also known as Kv1.6 is a protein that in humans is encoded by the KCNA6 gene. The protein encoded...
3 KB (414 words) - 13:28, 1 August 2023
voltage-gated potassium channel Kv1.1 with no effect on other tested potassium channels (Kv1.2, Kv1.3, Kv1.4, Kv1.5, Kv1.6, Shaker IR, Kv2.1, Kv3.1, Kv4...
10 KB (1,136 words) - 00:23, 23 December 2024
These 3 families differ in structure. Cobatoxin 1 and 2 both block the Kv1.1 K+-channels in mice and the Shaker B K+ channels in insects, which are...
4 KB (472 words) - 03:34, 29 December 2021
tomb of Ramesses IV, and is located low in the main valley, between KV7 and KV1. It has been open since antiquity and contains a large amount of graffiti...
8 KB (810 words) - 18:56, 16 September 2024