A knockout mouse, or knock-out mouse, is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing...

A knockout mouse is a genetically modified mouse that has had one or more of its genes made inoperable through a gene knockout. Experimental mouse model...

create knockout mice. With the aid of gene targeting, numerous mouse genes have been shut down, leading to the creation of hundreds of distinct mouse models...

William; Rosen, Barry; et al. (2011). "A conditional knockout resource for the genome-wide study of mouse gene function". Nature. 474 (7351): 337–342. doi:10...

postdoctoral fellow Arthur T Sands. The company has used its patented mouse gene knockout technology and extensive in vivo screening capabilities to study...

reducing the cost of research and experiments. The most common type is the knockout mouse, where the activity of a single (or in some cases multiple) genes are...

Nude mouse SCID mouse NOG mouse NSG mouse Mouse model of colorectal and intestinal cancer Mouse models of breast cancer metastasis Knockout mouse Chuprin...

KOMP 104.9 Radio Compa, an album by Akwid Knockout Mouse Program (KOMP), part of the International Knockout Mouse Consortium Comp (disambiguation) This disambiguation...

The International Knockout Mouse Consortium (IKMC) is a scientific endeavour to produce a collection of mouse embryonic stem cell lines that together...

that are unavailable in the mouse. Knockout rat models can also complement existing transgenic mouse models. Comparing mouse and rat mutants can facilitate...

therefore it is used even more. In 1993 the first C57BL/6 gene targeted knockout mouse was published by a group at Hoffmann-La Roche in Switzerland. In 2013...

Capecchi and Oliver Smithies, for his work in the development of the knockout mouse and the related technology of gene targeting, a method of using embryonic...

disorder. A mutation in one gene (TMEM63B) was identified in a large knockout mouse study as likely to result in disease in humans. In two patients, a small...

Mammals Mouse Knockout mouse Oncomouse Enviropig Herman the Bull Knockout rat Rabbit Other animals Insects Fish GloFish Salmon Birds Frogs...

ultimately lead to cancer due to the loss of function as a sensor. Runx3 null mouse gastric mucosa exhibits hyperplasia due to stimulated proliferation and...

this holds in vivo over longer time periods is not clear. The ABCR -/- knockout mouse has delayed dark adaptation but normal final rod threshold relative...

modeling. The National Institutes of Health (NIH) funds phase 2 of the Knockout Mouse Production and Phenotyping Project (KOMP2). Researchers link mutations...

activation by beta-endorphin in pons/medulla of the mu-opioid receptor knockout mouse". Neuroscience. 115 (3): 715–721. doi:10.1016/s0306-4522(02)00486-4...

HG; Gonzalez, FJ; Nebert, DW (2006). "Oral Benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required...

a major role in social reward in animals and the μ-opioid receptor knockout mouse is an animal model of autism. Studies on whether naltrexone can decrease...

"Schneckenbecken dysplasia". In 2007, Hiraoka et al. created an SLC35D1-knockout mouse model, said experiment revealed that while mice heterozygous for the...

sister. Capecchi was awarded the Nobel prize for creating a knockout mouse. This is a mouse, created by genetic engineering and in vitro fertilization...

G.; Carlson, M.; Lockridge, O. (2007). "The Butyrylcholinesterase Knockout Mouse as a Model for Human Butyrylcholinesterase Deficiency". Journal of Pharmacology...

K, Surendran S, Tyring SK (2006). "Canavan disease: studies on the knockout mouse". N-Acetylaspartate. Advances in Experimental Medicine and Biology....

conditional knockout mouse lines deficient in glycan-binding proteins or glycosyltransferases. All Core F strains are now archived at the Mutant Mouse Regional...

with a high GH secretion. An animal model of Laron syndrome, the GHR knockout mouse, shows severely impaired ductal outgrowth at 11 weeks of age. However...

(2002). "Behavioral and neuroanatomical characterization of the Fmr1 knockout mouse". Hippocampus. 12 (1): 39–46. doi:10.1002/hipo.10005. ISSN 1050-9631...

A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune...

Additionally, a double (SHH-/- ) knockout mouse model exhibited poor lung development. The lungs of the SHH double knockout failed to undergo lobation and...

Ramberg Capecchi (born 1937), and Oliver Smithies (1925–2017), U.S. – Knockout mouse, Gene targeting Ole Evinrude (1877–1934), Norway – outboard motor Charles...