• Thumbnail for Kynureninase
    Kynureninase or L-Kynurenine hydrolase (KYNU) (EC 3.7.1.3) is a PLP dependent enzyme that catalyses the cleavage of kynurenine (Kyn) into anthranilic acid...
    8 KB (941 words) - 06:52, 3 June 2024
  • Thumbnail for Kynurenine pathway
    brain. Also known as kynureninase deficiency, this extremely rare inherited disorder is caused by the defective enzyme kynureninase which leads to a block...
    23 KB (2,404 words) - 17:15, 11 April 2024
  • Thumbnail for Anthranilic acid
    now-widely outlawed euphoric sedative drug methaqualone (Quaalude, Mandrax). Kynureninase 3-Aminobenzoic acid 4-Aminobenzoic acid Methyl anthranilate "Front Matter"...
    13 KB (1,057 words) - 18:06, 15 August 2023
  • Category:EC 3.6.3 ATPase NaKATPase (EC 3.6.3.9) ATP synthase (EC 3.6.3.14) Kynureninase EC 3.7.1.3 EC 3.8.1.3 Haloacetate dehalogenase EC 3.9.1.1: Phosphoamidase...
    33 KB (3,650 words) - 18:48, 10 September 2024
  • have 2 main causes: Metabolic causes: Genetic defects in enzymes (e.g. kynureninase) involved in the kynurenine pathway of synthesis of niacin from tryptophan...
    49 KB (3,959 words) - 23:35, 27 October 2024
  • Thumbnail for Kynurenine
    deficits and depressive symptoms. Kynurenine is also associated with tics. Kynureninase catabolizes the conversion of kynurenine into anthranilic acid while...
    22 KB (2,128 words) - 05:02, 4 October 2024
  • Thumbnail for Indoleamine 2,3-dioxygenase
    Liver After Administration of Tryptophan, Kynurenine Metabolites, and Kynureninase Inhibitors". International Journal of Tryptophan Research. 9: 51–65....
    17 KB (1,976 words) - 03:43, 25 May 2024
  • Thumbnail for Kynurenic acid
    disorders, such as marked pyridoxine deficiency and deficiency/absence of kynureninase. When researchers decreased the levels of kynurenic acid in the brains...
    15 KB (1,400 words) - 02:18, 9 September 2024
  • N-formyl-L-kynurenine is converted to anthranilate by the pathway-specific kynureninase, AntP. 3. Anthranilate is activated by the acyl-CoA ligase protein, AntF...
    4 KB (486 words) - 13:20, 24 February 2023
  • Thumbnail for Kynurenine 3-monooxygenase
    kynurenic acid through kynurenine amino transferases, or anthranilic acid by kynureninase. Kynurenine 3-monooxygenase regulates the downstream production of quinolinic...
    18 KB (1,970 words) - 10:11, 22 March 2024
  • EC 3.7.1.1: oxaloacetase EC 3.7.1.2: fumarylacetoacetase EC 3.7.1.3: kynureninase EC 3.7.1.4: phloretin hydrolase EC 3.7.1.5: acylpyruvate hydrolase EC...
    119 KB (15,555 words) - 06:24, 19 September 2024
  • Thumbnail for CCDC188
    CXCL9 CXC Motif Chemokine Ligand 9 Antimicrobial protein 0.879 KYNU Kynureninase Biosynthesis of NAD cofactors from tryptophan 0.866 MASP1 Mannose-Binding...
    17 KB (1,184 words) - 22:02, 2 December 2023