DHX58 also known as RIG-I-like receptor 3 (RLR-3) or RIG-I-like receptor LGP2 (RLR) is a RIG-I-like receptor dsRNA helicase enzyme that in humans is encoded...
9 KB (1,101 words) - 12:27, 13 August 2023
(RLR) family. Together with MDA5 (melanoma differentiation-associated 5) and LGP2 (laboratory of genetics and physiology 2), this family of cytoplasmic pattern...
25 KB (3,011 words) - 17:07, 24 May 2024
part of the RIG-I-like receptor (RLR) family, which also includes RIG-I and LGP2, and functions as a pattern recognition receptor capable of detecting viruses...
18 KB (2,222 words) - 09:48, 7 July 2024
Differentiation-Associated protein 5 (MDA5) and Laboratory of genetics physiology 2 (LGP2). RIG-I and MDA5 are both involved in activating MAVS and triggering an antiviral...
23 KB (2,831 words) - 16:57, 27 August 2024
5'triphosphate-RNA and dsRNA, respectively), which activate antiviral signaling, and LGP2, which appears to act as a dominant-negative inhibitor. RLRs initiate the...
43 KB (5,173 words) - 21:02, 10 August 2024
33 DHX36 RHAU DEAH-Box Helicase 36 DHX57 DHX57 DExH-Box Helicase 57 DHX58 LGP2 DExH-Box Helicase 58 DIDO1 DIDO1 Death Inducer-Obliterator 1 DIS3L2 DIS3L2/FAM3A...
183 KB (12,458 words) - 20:40, 1 July 2024
sensors of viral replication by direct interaction with dsRNA RIG-I MDA5 LGP2 Secreted PRRs Complement system (see complement proteins section) Collectins...
38 KB (2,656 words) - 12:11, 30 October 2023