• Thumbnail for Leucyl aminopeptidase
    Leucyl aminopeptidases (EC 3.4.11.1, leucine aminopeptidase, LAPs, leucyl peptidase, peptidase S, cytosol aminopeptidase, cathepsin III, L-leucine aminopeptidase...
    14 KB (1,664 words) - 19:39, 30 June 2024
  • Thumbnail for Tripeptide
    Leupeptin (N-acetyl-L-leucyl-L-leucyl-L-argininal) is a protease inhibitor that also acts as an inhibitor of calpain Melanostatin (prolyl-leucyl-glycinamide) is...
    3 KB (341 words) - 20:00, 12 May 2024
  • Thumbnail for N-Formylmethionine-leucyl-phenylalanine
    N-Formylmethionyl-leucyl-phenylalanine (fMLF, fMLP or N-formyl-met-leu-phe) is an N-formylated tripeptide and sometimes simply referred to as chemotactic...
    15 KB (1,678 words) - 21:18, 6 April 2024
  • Bacterial leucyl aminopeptidase (EC 3.4.11.10, Aeromonas proteolytica aminopeptidase) is an enzyme. This enzyme catalyses the following chemical reaction...
    2 KB (163 words) - 13:17, 26 August 2023
  • Thumbnail for Insulin regulated aminopeptidase
    regulated aminopeptidase (IRAP) is a protein that in humans is encoded by the leucyl and cystinyl aminopeptidase (LNPEP) gene. IRAP is a type II transmembrane...
    32 KB (3,676 words) - 20:28, 16 December 2024
  • Thumbnail for Leucyl-tRNA synthetase
    Leucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the LARS gene. This gene encodes a cytosolic leucine-tRNA synthetase, a member...
    9 KB (963 words) - 08:54, 30 January 2024
  • reaction L-leucyl-tRNA + protein ⇌ {\displaystyle \rightleftharpoons } tRNA + L-leucyl-protein Thus, the two substrates of this enzyme are L-leucyl-tRNA and...
    2 KB (237 words) - 16:12, 22 September 2024
  • rginyl-L-arginyl-L-α-glutamyl-L-leucyl-L-leucyl-L-α-glutamyl-L-lysyl-L-leucyl-L-leucyl-2-methylalanyl-L-lysyl-L-leucyl-L-histidyl-L-threonyl-L-alaninamide...
    23 KB (1,979 words) - 16:13, 16 August 2024
  • Leucyl endopeptidase (EC 3.4.21.57, plant Leu-proteinase, leucine-specific serine proteinase, leucine endopeptidase, spinach serine proteinase (leucine...
    2 KB (169 words) - 14:44, 26 August 2023
  • Thumbnail for Melanocyte-inhibiting factor
    PMC 389210. PMID 5283931. Petersson M, Uvnäs-Moberg K (December 2004). "Prolyl-leucyl-glycinamide shares some effects with oxytocin but decreases oxytocin levels"...
    17 KB (1,892 words) - 23:03, 6 August 2024
  • Thumbnail for Retatrutide
    onyl-L-seryl-L-alpha -aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-2-methyl-L-leucyl-Lleucyl-L-alpha -aspartyl-L-lysyl-N6-(N-(19-carboxy-1-oxononadecyl)-L-g...
    4 KB (328 words) - 05:24, 6 August 2024
  • Thumbnail for Biuret test
    dipeptides and related substances. Part 5.—Cupric complexes of sarcosyl and leucyl ligands". Trans. Faraday Soc. 55: 2141–2151. doi:10.1039/TF9595502141. ISSN 0014-7672...
    10 KB (995 words) - 10:15, 12 August 2024
  • endopeptidase (NEP) Dipeptidyl peptidase 3 (DPP3) Carboxypeptidase A6 (CPA6) Leucyl/cystinyl aminopeptidase (LNPEP) Angiotensin-converting enzyme (ACE) Enkephalinase...
    2 KB (159 words) - 16:44, 22 September 2024
  • Thumbnail for Ganfeborole
    tuberculosis. It acts as a potent and selective inhibitor of the bacterial leucyl-tRNA synthetase enzyme, and is currently in clinical trials. Li X, Hernandez...
    3 KB (187 words) - 14:31, 21 September 2024
  • Thumbnail for Amastatin
    inhibits leucyl aminopeptidase, alanyl aminopeptidase (aminopeptidase M/N), bacterial leucyl aminopeptidase (Aeromonas proteolytica aminopeptidase), leucyl/cystinyl...
    5 KB (382 words) - 17:49, 13 February 2024
  • Thumbnail for Tavaborole
    US FDA in July 2014. The medication inhibits an essential fungal enzyme, leucyl-tRNA synthetase, that is required for protein synthesis. The inhibition...
    8 KB (610 words) - 20:02, 20 December 2023
  • Thumbnail for MG132
    mino}-1-oxopentan-2-yl]carbamate Other names N-Benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal Z-Leu-Leu-Leu-al Identifiers CAS Number 133407-82-6 Y 3D...
    5 KB (374 words) - 11:11, 10 September 2024
  • Thumbnail for Monocyte
    receptor agonists (e.g., 5-HETE and 5-oxo-ETE); and N-Formylmethionine leucyl-phenylalanine and other N-formylated oligopeptides which are made by bacteria...
    31 KB (3,227 words) - 02:17, 22 December 2024
  • Identifiers IUPAC name glycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-L-lysyl-L-leucyl-L-α-aspartyl-L-arginyl-L-isole...
    13 KB (1,374 words) - 21:56, 10 March 2024
  • amyl-L-α-glutamyl-L-valylL-isoleucyl-L-lysyl-L-leucyl-L-cysteinylglycyl-L-arginyl-L-α-glutamyl-L-leucyl-L-valyl-L- arginyl-L-alanyl-L-glutaminyl-L-iso...
    12 KB (1,043 words) - 06:49, 19 May 2024
  • Thumbnail for Leucine
    of mTOR by leucine is mediated through Rag GTPases, leucine binding to leucyl-tRNA synthetase, leucine binding to sestrin 2, and possibly other mechanisms...
    27 KB (4,132 words) - 00:11, 7 September 2024
  • Thumbnail for Oxytocin
    concentrations of vitamin C. Oxytocin is known to be metabolized by the oxytocinase, leucyl/cystinyl aminopeptidase. Other oxytocinases are also known to exist. Amastatin...
    110 KB (12,241 words) - 19:17, 17 December 2024
  • aspertetronin A, aspertetronin B, cyclo-L-isoleucyl-L-proline, cyclo-L-leucyl-L-proline, cyclo-L- valyl-L-proline, desferritriacetylfusigen, 3,30-Dihydroxy-5...
    2 KB (192 words) - 19:06, 13 January 2024
  • Thumbnail for Élie Metchnikoff
    including the most prominent member of this group, N-Formylmethionine-leucyl-phenylalanine, that are made by a variety of replicating gram positive bacteria...
    40 KB (4,071 words) - 10:58, 16 November 2024
  • giant African snail (Achatina fulica). Tentoxin (cyclo(N-methyl-L-alanyl-L-leucyl-N-methyl-trans-dehydrophenyl-alanyl-glycyl)) is a natural cyclic tetrapeptide...
    15 KB (1,938 words) - 23:35, 30 July 2024
  • Thumbnail for BC-LI-0186
    BC-LI-0186 is a compound that acts as an inhibitor of the GTPase enzyme leucyl-tRNA synthetase (LRS). This enzyme acts as part of the mTOR complex and...
    3 KB (255 words) - 21:09, 28 April 2024
  • in common use include leucyl-tRNA synthetase, leucyl-transfer ribonucleate synthetase, leucyl-transfer RNA synthetase, leucyl-transfer ribonucleic acid...
    3 KB (292 words) - 15:49, 22 September 2024
  • Thumbnail for Sermorelin
    -lysyl-L-valyl-L-leucylglycyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-L-meth...
    11 KB (736 words) - 14:38, 2 November 2024
  • Thumbnail for Leupeptin
    Leupeptin, also known as N-acetyl-L-leucyl-L-leucyl-L-argininal, is a naturally occurring protease inhibitor that can inhibit cysteine, serine and threonine...
    3 KB (224 words) - 10:08, 2 July 2022
  • Thumbnail for N-Formylmethionine
    immunity. The prototypical fMet-containing oligopeptide is N-formylmethionine-leucyl-phenylalanine (FMLP) which activates leukocytes and other cell types by...
    11 KB (1,188 words) - 21:01, 6 November 2024