Leukotriene C4 synthase is an enzyme that in humans is encoded by the LTC4S gene. The protein encoded by this gene, LTC4S (or glutathione S-transferase...

The enzyme leukotriene-C4 synthase (EC 4.4.1.20) catalyzes the reaction leukotriene C4 ⇌ {\displaystyle \rightleftharpoons } leukotriene A4 + glutathione...

Leukotriene C4 (LTC4) is a leukotriene. LTC4 has been extensively studied in the context of allergy and asthma. In cells of myeloid origin such as mast...

LTC4 synthase, such as mast cells and eosinophils, LTA4 is conjugated with the tripeptide glutathione to form the first of the cysteinyl-leukotrienes, LTC4...

Leukotriene A4 (LTA4) is a leukotriene, and is the precursor for the productions of leukotriene B4 (LTB4) and leukotriene C4 (LTC4). Following the biosynthesis...

antileukotriene, also known as leukotriene modifier and leukotriene receptor antagonist, is a medication which functions as a leukotriene-related enzyme inhibitor...

Leukotriene C4 synthase deficiency is an inborn error of metabolism. Deficiency of Leukotriene C4 synthase can lead to a reduction in Leukotriene C4. Mayatepek...

Other leukotrienes that function in a similar manner are leukotrienes C4 and E4. Pharmacological agents that inhibit the function of these leukotrienes are...

Montelukast is in the leukotriene receptor antagonist family of medications. It works by blocking the action of leukotriene D4 in the lungs resulting...

protein (gene FLAP), leukotriene C4 synthase (EC 2.5.1.37), which catalyzes the production of leukotriene C4 (LTC4) from leukotriene A4 (LTA4), and microsomal...

Leukotriene E4 (LTE4) is a cysteinyl leukotriene involved in inflammation. It is known to be produced by several types of white blood cells, including...

Leukotriene B4 (LTB4) is a leukotriene involved in inflammation. It has been shown to promote insulin resistance in obese mice. LTB4 is a leukotriene...

PMID 10703053. Gehlert R, Schoeppner A, Kindl H (1990). "Stilbene Synthase from Seedlings of Pinus sylvestris: Purification and Induction in Response...

Helenalin can inhibit certain enzymes, such as 5-lipoxygenase and leukotriene C4 synthase. For this reason the compound or its derivatives may have potential...

elongation and unsaturation. AA is the precursor to some prostaglandins, leukotrienes (LTA, LTB, LTC), thromboxane (TXA) and the N-acylethanolamine (NAE)...

arachidonate 5-lipoxygenase produces no leukotrienes and the conversion by the enzyme of arachidonic acid to leukotrienes is inhibited. GLA is categorized as...

leukotriene A4 which is then metabolized to the chemotactic factor for leukocytes, leukotriene B4, or to contractors of lung airways, leukotriene C4,...

proteins: Leukotriene B4 receptors (BLTRs) – bind to and are activated by LTB4: BLT1 (Leukotriene B4 receptor 1) – LTB4R BLT2 (Leukotriene B4 receptor...

Söderström M, Hammarström S (April 2009). "Distinct parts of leukotriene C(4) synthase interact with 5-lipoxygenase and 5-lipoxygenase activating protein"...

LTC4STooltip Leukotriene C4 synthase Azelastine MK-886 LTC4HTooltip Leukotriene C4 hydrolase Acivicin Serine-borate complex LTD4Tooltip Leukotriene D4 hydrolase...

LTC4STooltip Leukotriene C4 synthase Azelastine MK-886 LTC4HTooltip Leukotriene C4 hydrolase Acivicin Serine-borate complex LTD4Tooltip Leukotriene D4 hydrolase...

which in turn converts to various leukotrienes (i.e., leukotriene B4, leukotriene C4, leukotriene D4, and leukotriene E4) as well as to 5-hydroxyeicosatetraenoic...

the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity...

Minocycline is also known to indirectly inhibit inducible nitric oxide synthase. A trial found no difference between minocycline and placebo in people...

Leukotriene-C4 hydrolase (EC 3.4.19.14, gamma-glutamyl leukotrienase) is an enzyme. Gamma-glutamyltransferase 5 (GGT5) is a human gene which encodes an...

Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes ... 2. Prostaglandin G/H synthase 1 ... General function:...

epoxide, leukotriene A4 LTA4, which is then either rapidly converted to leukotriene B4 (LTB4) by leukotriene-A4 hydrolase (LTA4H) or to leukotriene C4 (LTC4)...

S-transferase with leukotriene C4 synthase activity and significant sequence identity to 5-lipoxygenase-activating protein and leukotriene C4 synthase". J Biol...

Leukotriene-A4 hydrolase is an enzyme that catalyzes the reaction which converts Leukotriene A4 to Leukotriene B4. It is a bifunctional zinc enzyme (EC...

synthase and CYP2C9 may predict how a person reacts to zafirlukast treatment. Zafirlukast (brand name Accolate) was the first cysteinyl leukotriene receptor...