Low complexity regions (LCRs) in protein sequences, also defined in some contexts as compositionally biased regions (CBRs), are regions in protein sequences...

Computational methods can study protein sequences to identify regions with low complexity, which can have particular properties regarding their function...

palindromes in peptides might be related to the prevalence of low-complexity regions in proteins, as palindromes are frequently associated with low-complexity sequences...

palindromes in peptides might be related to the prevalence of low-complexity regions in proteins, as palindromes frequently are associated with low-complexity sequences...

C, Iliopoulos I, Promponas V, et al. (November 2019). "Low complexity regions in the proteins of prokaryotes perform important functional roles and are...

histidine-rich low-complexity regions are found in metal-binding and especially nickel-cobalt binding proteins. These histidine-rich low complexity regions have...

linkers in large multi-domain proteins. They are sometimes considered as a separate class of proteins along with globular, fibrous and membrane proteins. IDPs...

the human genome project and the large diversity of proteins seen in an organism: different proteins encoded by the same gene could increase the diversity...

the presence of low-complexity region/regions. Low-complexity regions are regions in the sequence with only a few amino acids, which in turn, causes redundancy...

leucine-rich repeat proteins, which specifically bind some globular proteins by their concave surfaces; and zinc-finger proteins, which regulate the expression...

produced from protein-coding genes contains untranslated regions at both ends which contain binding sites for ribosomes, RNA-binding proteins, miRNA, as...

structural differences in proteins and their immunogenicity. Specifically, the irregular curl and low bond energy of the G protein make it prone to conformational...

NV (1 January 2004). "Gaps in structurally similar proteins: towards improvement of multiple sequence alignment". Proteins. 54 (1): 71–87. doi:10.1002/prot...

(PIR). A protein family comprises proteins with the same function in different organisms (orthologous sequences) but may also include proteins in the same...

and ultimately affect a phenotype. These products are often proteins, but in non-protein-coding genes such as transfer RNA (tRNA) and small nuclear RNA...

sequence. This sequence is called a Prion-Like Domain (PLD). PLDs are low complexity sequences that have been reported to mediate gene regulation via Liquid-Liquid...

Protein sequence can be used to predict local features, such as segments of secondary structure, or trans-membrane regions. However, the complexity of...

specific proteins. The sequence of nucleobases on a nucleic acid strand is translated by cell machinery into a sequence of amino acids making up a protein strand...

alignment is provided. FASTA can remove complexity regions before aligning the sequences by encoding low complexity regions in lower case and using the -S option...

tBLASTn tBLASTn used to search for proteins in sequences that haven't been translated into proteins yet. It takes a protein sequence and compares it to all...

Protein engineering is the process of developing useful or valuable proteins through the design and production of unnatural polypeptides, often by altering...

transmembrane protein expressed in neurons. It contains up to seven potential transmembrane domains separated by regions of low complexity. Functionally...

flavor and odorant compounds by breaking down macronutrients. Soy proteins and grain proteins are hydrolyzed into short peptide chains and free amino acids...

demonstrated that non-secreted proteins were translated by free ribosomes in the cytosol, while secreted proteins (and target proteins, in general) were translated...

The charge of proteins is determined by the pKa of its amino acid side chains, and the terminal amino acid and carboxylic acid. Proteins with isoelectric...

example, lysine and arginine are present in large amounts in the low-complexity regions of nucleic-acid binding proteins. There are various hydrophobicity scales...

genome. Human genomes include both protein-coding DNA sequences and various types of DNA that does not encode proteins. The latter is a diverse category...

promotes less vigour in the vine, which can keep yields low. In the Napa Valley wine regions of Oakville and Rutherford, the soil is more alluvial and...

the genome. The remaining mitochondrial proteins, metabolic enzymes, DNA and RNA polymerases, ribosomal proteins, and mtDNA regulatory factors are all encoded...

biochemistry of protein domains of low sequence complexity that are now recognized to comprise ~25% of eukaryotic proteomes and to function broadly in eukaryotic...