genes. MALAT1 may play a role in temperature-dependent sex determination in the Red-eared slider turtle (Trachemys scripta). Transcripts of MALAT1 are significantly...
11 KB (1,228 words) - 19:34, 2 October 2024
MALAT1-associated small cytoplasmic RNA, also known as mascRNA, is a non-coding RNA found in the cytosol. This is a small RNA, roughly 53–61 nucleotides...
4 KB (493 words) - 09:40, 18 August 2023
proper telomerase functioning. The triple helix at the 3' end of the PAN and MALAT1 long-noncoding RNAs serves to stabilize the RNA by protecting the Poly(A)...
12 KB (1,553 words) - 19:12, 4 August 2024
Mao YS, Lazar Z, Hung G, Bhattacharjee G, et al. (July 2012). "The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory...
40 KB (4,617 words) - 07:21, 2 November 2024
renal cell carcinoma. The t(6;11)(p21;q12) translocation fuses the Alpha (MALAT1) gene with the TFEB transcription factor gene, resulting in upregulated...
1 KB (104 words) - 18:57, 13 April 2021
case to date. In four cases described a mutation - a fusion between the MALAT1 and GLI1 genes - has been described. This fusion causes over expression...
5 KB (567 words) - 23:42, 26 July 2023
stability. Malat1, another neurological lncRNA, causes increased synaptic function and greater amounts of dendrite development. Increases of Malat1 increase...
45 KB (6,147 words) - 19:46, 29 June 2024
; Kingston, Robert E. (2014-09-04). "The Long Noncoding RNAs NEAT1 and MALAT1 Bind Active Chromatin Sites". Molecular Cell. 55 (5): 791–802. doi:10.1016/j...
22 KB (2,305 words) - 16:56, 26 June 2024
pathogenesis, which are metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), H19, maternally expressed gene 3 (MEG3), prostate cancer antigen 3 (PCA3)...
25 KB (2,873 words) - 03:45, 6 January 2024
non-small cell lung cancer, oral squamous cell carcinoma and colorectal cancer. MALAT1 (also known as NEAT2) was originally identified as an abundantly expressed...
121 KB (13,135 words) - 10:24, 9 November 2024
Romeo, Enrica; Raimondi, Lavinia (September 2018). "Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers...
10 KB (1,142 words) - 05:31, 14 March 2024
(paraspeckles), and determining that knockout or knockdown of the lncRNA Malat1 results in the differentiation of mammary tumors and a significant reduction...
12 KB (1,187 words) - 15:57, 17 January 2024
but the female mice exhibit decreased fertility and lactation defect. MALAT1-associated small cytoplasmic RNA Long non-coding RNA GRCh38: Ensembl release...
8 KB (843 words) - 00:03, 3 December 2023
Nucleus presence markers: Detection of nuclear specific genes (such as Malat1 in mammals) and increased ratio of intronic reads provide evidence for nucleus...
43 KB (5,261 words) - 16:24, 6 December 2023
to rescue aging-mediated impairment of endothelial cell function. LncRNA MALAT1 was found to regulate endothelial cell function and vessel growth. and protects...
118 KB (15,449 words) - 16:35, 18 July 2024