protein 8 (mLST8) or TORC subunit LST8 or G protein beta subunit-like (GβL or Gable), is a protein that in humans is encoded by the MLST8 (MTOR associated...
6 KB (810 words) - 15:16, 5 April 2024
the S1859 site downstream of mTORC1 signaling. CAD is also regulated by mLST8, an mTORC1/2 component. Congenital disorder of glycosylation, Type Iz is...
9 KB (1,156 words) - 15:08, 5 January 2024
regulatory-associated protein of mTOR (Raptor), mammalian lethal with SEC13 protein 8 (mLST8) and the non-core components PRAS40 and DEPTOR. This complex functions as...
119 KB (12,658 words) - 19:25, 19 September 2024
as raptor), mammalian lethal[clarification needed] with SEC13 protein 8 (MLST8), PRAS40 and DEPTOR. This complex embodies the classic functions of mTOR...
69 KB (7,807 words) - 19:19, 19 September 2024
HGNC:7141 P12872 9639 MLNR HGNC:4495 O43193 9640 MLPH HGNC:29643 Q9BV36 9641 MLST8 HGNC:24825 Q9BVC4 9642 MLX HGNC:11645 Q9UH92 9643 MLXIP HGNC:17055 Q9HAP2...
277 KB (17 words) - 18:41, 6 October 2024
binds rapamycin. In addition to mTOR, the TORC2 complex contains RICTOR, mLST8, and SIN1 and regulates insulin action and Akt phosphorylation. Thus, mTOR...
17 KB (1,932 words) - 02:07, 11 June 2024
mammalian LST8 (mLST8), and two negative regulators, proline-rich AKT substrate 40 (PRAS40) and DEPTOR. mTORC2 consists of mTOR, mLST8, mSin1, protor,...
57 KB (6,280 words) - 19:28, 19 September 2024
mTOR-interacting protein (DEPTOR), mammalian lethal with sec-13 protein 8 (mLST8, also known as GβL), and TTI1/TEL2 complex are shared by both mTORC2 and...
34 KB (3,791 words) - 19:30, 19 September 2024
12325. PMC 4406678. PMID 25678027. Lu, A (2016). "Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum". Nature Communications...
25 KB (2,130 words) - 07:15, 7 October 2024
Crimmins EM, Lunnon K, et al. (February 2016). "Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum". Nature Communications...
67 KB (7,187 words) - 04:41, 19 October 2024
mammalian target of rapamycin complex 1 (mTORC1). This complex contains mTOR, MLST8, RPTOR, AKT1S1/PRAS40, and DEPTOR. mTORC1 both binds to and is inhibited...
32 KB (3,504 words) - 19:00, 11 April 2024