Macrocycles are often described as molecules and ions containing a ring of twelve or more atoms. Classical examples include the crown ethers, calixarenes...
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view of heme, a complex of a protoporphyrin IX. A macrocycle of 40 porphyrin molecules, model A macrocycle of 40 porphyrin molecules, STM image A geoporphyrin...
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Sports periodization (section The macrocycle)
time up into three types of cycles: microcycle, mesocycle, and macrocycle. A macrocycle refers to a season of training in its entirety. It is an annual...
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hemoglobin and chlorophyll. In these two molecules, in particular, the pyrrole macrocycle ring frames a metal atom, that forms a coordination compound with the...
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Cyclic compound (section Macrocycles)
regular use.[citation needed] The term macrocycle is used for compounds having a rings of 8 or more atoms. Macrocycles may be fully carbocyclic (rings containing...
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consisting of a dumbbell-shaped molecule which is threaded through a macrocycle (see graphical representation). The two components of a rotaxane are kinetically...
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Cyclic peptide (redirect from Peptide macrocycle)
Cyclic peptides are polypeptide chains which contain a circular sequence of bonds. This can be through a connection between the amino and carboxyl ends...
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Catenane (category Macrocycles)
interlocked molecular architecture consisting of two or more interlocked macrocycles, i.e. a molecule containing two or more intertwined rings. The interlocked...
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of the macrocycle ring absorbs visible light. The nature of the central metal can also influence the absorption spectrum of the metal-macrocycle complex...
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iron atom is at the centre of a porphyrin macrocycle, bound to four nitrogen atoms of the tetrapyrrole macrocycle. The very stable dimethylglyoximate complex...
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Cyclodextrin (category Macrocycles)
1002/14356007.e08_e02. ISBN 978-3527306732. Gu A, Wheate N (2021). "Macrocycles as drug-enhancing excipients in pharmaceutical formulations". Journal...
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E (May 1980). "Biosynthesis of the pigments of life: formation of the macrocycle". Nature. 285 (5759): 17–21. Bibcode:1980Natur.285...17B. doi:10.1038/285017a0...
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Dynamic covalent chemistry (section Macrocycles)
as covalent organic frameworks, molecular knots, polymers, and novel macrocycles. Not to be confused with dynamic combinatorial chemistry, DCvC concerns...
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are bacteriochlorins, meaning their molecules have a bacteriochlorin macrocycle ring with two reduced pyrrole rings (B and D). Bacteriochlorophylls c...
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cyclizes the molecule, yielding the unbound product, prerapamycin. The core macrocycle, prerapamycin (figure 2), is then modified (figure 3) by an additional...
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charge-transfer complexes. Porphyrins have conjugated molecular ring systems (macrocycles) that appear in many enzymes of biological systems. As a ligand, porphyrin...
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Michel (1999). "Gold(I) and Gold(0) Complexes of Phosphinine‐Based Macrocycles". Angewandte Chemie International Edition. 38 (21): 3194–3197. doi:10...
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anemia. Fludara (Fludarabine), for leukemia. Mozobil (Plerixafor), for macrocycle, approved by the FDA for peripheral blood stem cell mobilizer for non-Hodgkin's...
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Cyanostar (category Macrocycles)
A cyanostar (pentacyanopentabenzo[25]annulene) is a shape-persistent macrocycle that binds anions. The cyanostar structure is synthesized in a one-pot...
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cations tend to form stronger complexes, but when large polydentate macrocycles are involved the trend is reversed. Though calcium is in the same group...
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some amino acids, such as glycine. Heme B is the porphyrin derivative macrocycle molecule that holds the iron atom in place in hemoglobin, allowing for...
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natural products such as heme. Pyrroles are components of more complex macrocycles, including the porphyrinogens and products derived therefrom, including...
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most stable rings contain five or six carbon atoms, but large rings (macrocycles) and smaller rings are common. The smallest cycloalkane family is the...
39 KB (4,396 words) - 08:54, 25 October 2024
Michel (1999). "Gold(I) and Gold(0) Complexes of Phosphinine‐Based Macrocycles". Angewandte Chemie International Edition. 38 (21): 3194–3197. doi:10...
47 KB (8,698 words) - 02:26, 27 October 2024
abbreviated as PPIX. Protoporphyrin IX contains a porphine core, a tetrapyrrole macrocycle with a marked aromatic character. Protoporphyrin IX is essentially planar...
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carbohydrates) and large non-polymeric molecules such as lipids, nanogels and macrocycles. Synthetic fibers and experimental materials such as carbon nanotubes...
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Phthalocyanine (category Macrocycles)
derivatives of the parent phthalocyanine, where either carbon atoms of the macrocycle are exchanged for nitrogen atoms or the peripheral hydrogen atoms are...
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Macrocyclic ligand (category Macrocycles)
synthesis of the "Curtis macrocycles", in which a metal ion serves as a template for ring formation. Polyether macrocycles - or "crown" ligands - were...
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price of linaclotide to around $414 in 2018. Oh SA (17 August 2011). "Macrocycle Milestone for Ironwood Pharma". The Haystack. Archived from the original...
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tetrapyrrolic molecules, with the heart of the skeleton a heterocyclic macrocycle, known as a porphine. The fundamental porphine frame consists of four...
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