Maleimide is a chemical compound with the formula H2C2(CO)2NH (see diagram). This unsaturated imide is an important building block in organic synthesis...

In enzymology, a maleimide hydrolase (EC 3.5.2.16) is an enzyme that catalyzes the chemical reaction maleimide + H2O ⇌ {\displaystyle \rightleftharpoons...

chromatography. TCEP is particularly useful when labeling cysteine residues with maleimides. TCEP can keep the cysteines from forming di-sulfide bonds and, unlike...

DA-step-growth furan-maleimide based polymer (3M4F) were demonstrated by subjecting it to heating/cooling cycles. Tris-maleimide (3M) and tetra-furan...

Ramachandra S.; Liebman, Joel F. (1997). "The Elusive Antiaromaticity of Maleimides and Maleic Anhydride: Enthalpies of Formation of N-Methylmaleimide, N-Methylsuccinimide...

brentuximab (cAC10, which targets the cell-membrane protein CD30) linked with maleimide attachment groups, cathepsin-cleavable linkers (valine-citrulline), and...

Eosin-5-maleimide binding test: Positive (reduced mean fluorescence), as the test will demonstrate a reduced ability of the eosin-5-maleimide dye to bind...

acid forms esters, an imide, and an anhydride, i.e. diethyl maleate, maleimide, and maleic anhydride. Fumaric acid, as fumarate, is an intermediate in...

which ends in a highly reactive moiety such as N-hydroxysuccinimide or maleimide. Many analogs of standard Cy 2 / 3 / 3.5 / 5 / 5.5 / 7 / 7.5 dyes were...

T in the name. In presence of a bismaleimide, the double bond of the maleimide group can copolymerize with the cyano groups to heterocyclic 6-membered...

carboxylate, isothiocyanate, hydrazine), carboxyl groups (carbodiimide), thiol (maleimide, acetyl bromide), and organic azide (via click chemistry or non-specifically...

carboxyfluorescein 3.2 488 Alexa 488 1.96, 4.35 22.5±0.5 488 Atto 655-maleimide 4.07 ± 0.1 25 663 Atto 655-carboxylicacid 4.26 ± 0.08 25 663 2′, 7′-difluorofluorescein...

susceptibility (χ) −78.4×10−6 cm3/mol Related compounds Related Amides Maleimide Related compounds Phthalic anhydride Except where otherwise noted, data...

fumaric acid succinic acid crotonic acid Related compounds maleic anhydride maleimide Except where otherwise noted, data are given for materials in their standard...

SO, Hunter JH, Anderson ME, et al. (October 2014). "Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody–drug...

labeling experiments to investigate biomolecular structure and dynamics. Maleimides selectively attach to cysteine using a covalent Michael addition. Site-directed...

that contains two reactive functional groups, a succinimide ester and a maleimide. The succinimide group of SMCC reacts with the free amino group of a lysine...

reactions are often reversible at high temperatures. In the case of furan–maleimide adducts, the retro-cycloaddition is accessible at temperatures as low...

Functional groups like alkyne, norbornene, maleimide, nitrite, and cyanate have been used for this purpose. Maleimide and norbornene end-capped oligomers can...

Safety data sheet (SDS) External MSDS Related compounds Related Imides Maleimide, N-Chlorosuccinimide, N-Bromosuccinimide Except where otherwise noted...

spacer is needed. Preferred end groups for heterobifunctional PEGs are maleimide, vinyl sulfones, pyridyl disulfide, amine, carboxylic acids and NHS esters...

transferrin-antibody were connected using a SMCC bifunctional linker (NHS ester and maleimide moiety) to radiolabelled and cys-bearing ASOs targeting HIV mRNA. Marcin...

Pencolide is a maleimide isolate of Penicillium and seaweed endophytic fungi. Birkinshaw, JH; Kalyanpur, MG; Stickings, CE (1963). "Studies in the biochemistry...

two reactive groups at opposite ends: N-hydroxysuccinimide-ester and maleimide, reactive with amines and thiols respectively. SMCC is often used in bioconjugation...

contrast for breast carcinoma imaging in mice. Biotin-Peg2-Amine Biotin-Peg2-Maleimide Biotin-Peg3-Amine Biotin-Peg4-NHS Mono BOC Cystamine[permanent dead link‍]...

Grigorieff N (Sep 2003). "Electron cryomicroscopy structure of N-ethyl maleimide sensitive factor at 11 A resolution". The EMBO Journal. 22 (17): 4365–74...

carboxyhemoglobin which is currently in late clinical development. Similarly, maleimide PEG conjugated human carboxyhemoglobin had previously been the subject...

crosslinker Sulfo-SMCC, which converts lysine residues to sulfhydryl-reactive maleimide groups. A sulfhydryl-containing hapten can then be reacted with the KLH...

quenching by a stereospecific Diels-Alder reaction with the substituted maleimide. In particular, the syn-substituted product gave the anti-WH product,...

cathepsin-cleavable linker is blue, and the attachment group (consisting of maleimide and caproic acid) is brown. The whole radical inside the four boxes is...