Malonyl-CoA is a coenzyme A derivative of malonic acid. It plays a key role in chain elongation in fatty acid biosynthesis and polyketide biosynthesis...
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(acyl-carrier-protein) S-malonyltransferase (redirect from Malonyl coenzyme A:acyl carrier protein transacylase)
this enzyme class is malonyl-CoA:[acyl-carrier-protein] S-malonyltransferase. Other names in common use include malonyl coenzyme A-acyl carrier protein...
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Coenzyme A (CoA, SHCoA, CoASH) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the...
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Watanabe M, Kawase Y, Jishage K, Lopaschuk GD (2006). "Absence of Malonyl Coenzyme A Decarboxylase in Mice Increases Cardiac Glucose Oxidation and Protects...
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PMID 18079405. Alber B, Olinger M, Rieder A, Kockelkorn D, Jobst B, Hügler M, Fuchs G (December 2006). "Malonyl-coenzyme A reductase in the modified 3-hydroxypropionate...
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interaction with the coenzyme A moiety. It has been suggested that malonyl-CoA may behave as a competitive inhibitor of CPT1A at this site. A second "O site"...
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Malonic aciduria (redirect from Malonyl-CoA decarboxylase deficiency)
Malonic aciduria or malonyl-CoA decarboxylase deficiency (MCD) is an autosomal-recessive metabolic disorder caused by a genetic mutation that disrupts...
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Acetyl-CoA (redirect from Acetyl coenzyme A)
Acetyl-CoA (acetyl coenzyme A) is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism. Its main function...
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Isoflavone-7-O-beta-glucoside 6"-O-malonyltransferase (redirect from Malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase)
malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase, MAT-7, malonyl-coenzyme A:isoflavone 7-O-glucoside-6"-malonyltransferase, and malonyl-coenzyme...
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Flavonol-3-O-beta-glucoside O-malonyltransferase (redirect from Malonyl-CoA:flavonol-3-O-beta-D-glucoside 6''-O-malonyltransferase)
malonyl-coenzyme A:flavonol-3-O-glucoside malonyltransferase. Matern U, Feser C, Hammer D (1983). "Further characterization and regulation of malonyl-coenzyme...
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3-Hydroxypropionic acid (category Wikipedia articles incorporating a citation from the 1911 Encyclopaedia Britannica with Wikisource reference)
reached a commercial stage. It can also be produced from glucose via pyruvate and malonyl coenzyme A. 3-Hydroxypropionic acid is of interest as a bio-derived...
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3-hydroxyacyl-coenzyme A Medium-chain acyl-coenzyme A dehydrogenase deficiency (MCAD) - Medium-chain acyl-coenzyme A dehydrogenase Short-chain acyl-coenzyme A dehydrogenase...
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Malonyl-CoA decarboxylase (EC 4.1.1.9), (which can also be called MCD and malonyl-CoA carboxyl-lyase) is found in bacteria and humans and has important...
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Malonic acid (redirect from Malonyl)
is converted to malonyl-CoA by acyl-CoA synthetase family member 3 (ACSF3). Additionally, the coenzyme A derivative of malonate, malonyl-CoA, is an important...
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synthesis. XVII. Preparation and general properties of acetyl coenzyme A and malonyl coenzyme A-acyl carrier protein transacylases". J. Biol. Chem. 241 (10):...
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Mupirocin (redirect from Pseudomonic acid A)
acetyl-Coenzyme A (CoA) to the first ACP domain. The chain is extended by malonyl-CoA, followed by a SAM-dependent methylation at C12 (see Figure 2 for PA-A...
30 KB (2,604 words) - 19:53, 17 August 2024
Combined malonic and methylmalonic aciduria (category Vitamin, coenzyme, and cofactor metabolism disorders)
Gregg, A. R.; Warman, A. W.; Thorburn, D. R.; O'Brien, W. E. (1998). "Combined malonic and methylmalonic aciduria with normal malonyl-coenzyme A decarboxylase...
32 KB (3,294 words) - 15:59, 4 August 2024
malonyl coenzyme A (after decarboxylation). This process produces 3-ketoacyl-CoA's as intermediates. The C=O (keto) group is replaced with CH2 via a series...
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Fatty-acyl-CoA synthase (redirect from Acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl- reducing))
FAS catalysis mechanism consumes an acetyl coenzyme A (acetyl-CoA) and seven malonyl-CoA molecules to produce a palmitoyl-CoA. Synthesis of fatty acids is...
15 KB (1,675 words) - 08:43, 10 July 2024
"Combined malonic and methylmalonic aciduria with normal malonyl-coenzyme A decarboxylase activity: a case supporting multiple aetiologies". Journal of Inherited...
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Anthocyanin 6"-O-malonyltransferase (redirect from Malonyl-CoA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase)
Cloning, Heterologous Expressions, and Functional Characterization of Malonyl-Coenzyme A:Anthocyanidin 3-O-Glucoside-6"-O-Malonyltransferase from Dahlia Flowers"...
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Stern JR (1960). "Enzymic synthesis and metabolism of malonyl coenzyme A and glutaryl coenzyme A". J. Biol. Chem. 235 (12): 3393–3398. doi:10.1016/S0021-9258(18)64478-3...
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Menendez C, Schägger H, Fuchs G (May 2002). "Malonyl-coenzyme A reductase from Chloroflexus aurantiacus, a key enzyme of the 3-hydroxypropionate cycle...
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Acetoacetyl-CoA synthase (redirect from Acetyl-CoA:malonyl-CoA C-acetyltransferase (decarboxylating))
acetyl-CoA:malonyl-CoA C-acetyltransferase (decarboxylating). This enzyme catalyses the following chemical reaction acetyl-CoA + malonyl-CoA ⇌ {\displaystyle...
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Cinnamoyl-CoA (redirect from Cinnamoyl-Coenzyme A)
Cinnamoyl-coenzyme A is an intermediate in the phenylpropanoid metabolic pathway. Cinnamoyl-CoA reductase, an enzyme that catalyzes the chemical reaction...
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(KS), releasing acetyl CoA to generate malonyl-CoA. This reaction undergoes chain elongation using malonyl-coenzyme A (CoA) following ketoreductase (CLF,...
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Fatty acid synthase (redirect from Acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing))
palmitate (C16:0, a long-chain saturated fatty acid) from acetyl-CoA and malonyl-CoA, in the presence of NADPH. The fatty acids are synthesized by a series of...
35 KB (4,020 words) - 10:13, 27 March 2024
Biotin (redirect from Coenzyme R)
serves as the carbon dioxide carrier in carboxylation reactions. Biotin is a coenzyme for five carboxylase enzymes, which are involved in the catabolism of...
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Klebsiella pneumoniae catalyses the turnover of acetyl and malonyl thioester residues on a coenzyme-A-like prosthetic group". European Journal of Biochemistry...
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Guynn RW, Veloso D, Veech RL (November 1972). "The concentration of malonyl-coenzyme A and the control of fatty acid synthesis in vivo". J. Biol. Chem. 247...
22 KB (2,740 words) - 14:47, 26 August 2023