• Mannose-binding protein-associated serine protease are serine proteases involved in the complement system. Types include: MASP1 MASP2 mannan-binding lectin...
    1 KB (122 words) - 14:24, 29 March 2024
  • Thumbnail for Mannan-binding lectin
    Mannose-binding lectin (MBL), also called mannan-binding lectin or mannan-binding protein (MBP), is a lectin that is instrumental in innate immunity as...
    17 KB (2,127 words) - 19:30, 18 May 2024
  • Thumbnail for MASP2 (protein)
    Mannan-binding lectin serine protease 2 also known as mannose-binding protein-associated serine protease 2 (MASP-2) is an enzyme that in humans is encoded...
    11 KB (1,482 words) - 01:56, 4 January 2024
  • Mannan-binding lectin-associated serine protease-2 (EC 3.4.21.104, MASP-2, MASP2, MBP-associated serine protease-2, mannose-binding lectin-associated serine...
    4 KB (466 words) - 14:52, 26 August 2023
  • Thumbnail for Complement system
    Such binding leads to conformational changes in the C1q molecule, which leads to the activation of two C1r molecules. C1r is a serine protease. They...
    43 KB (5,014 words) - 19:53, 25 May 2024
  • Thumbnail for MASP1 (protein)
    Mannan-binding lectin serine protease 1 also known as mannose-associated serine protease 1 (MASP-1) is an enzyme that in humans is encoded by the MASP1...
    18 KB (2,168 words) - 09:47, 27 February 2024
  • complement system. Specifically, mannose binding triggers recruitment of MBL-associated serine proteases (MASPs). The serine proteases activate themselves in a...
    43 KB (5,165 words) - 05:18, 16 June 2024
  • Thumbnail for Dengue virus
    protein until the viral particle has exited the cell. The DENV NS3 is a serine protease, as well as an RNA helicase and RTPase/NTPase. The protease domain...
    53 KB (6,368 words) - 15:17, 27 June 2024
  • Thumbnail for Lectin pathway
    MBL form a complex with MASP1 (Mannose-binding lectin-Associated Serine Protease), MASP2 and MASP3, that are protease zymogens. The MASPs are very similar...
    7 KB (875 words) - 13:26, 8 June 2024
  • of mannose-6-phosphate is accomplished by two proteins: CI-MPR (cation-independent mannose-6-phosphate receptor) and CD-MPR (cation-dependent mannose-6-phosphate...
    26 KB (3,161 words) - 19:09, 8 June 2024
  • Thumbnail for Phagocytosis
    these granules are proteases, such as collagenase, gelatinase or serine proteases, myeloperoxidase, lactoferrin and antibiotic proteins. Degranulation of...
    22 KB (2,451 words) - 08:23, 28 May 2024
  • Ficolin (category Blood proteins)
    facilitated by the mannose-binding protein-associated serine proteases (MASPs) that ficolins are associated to and co-circulate with. Serine proteases then cleave...
    7 KB (829 words) - 06:25, 13 May 2024
  • ribonucleoprotein K (HNRPK), transcript PABPN1 poly(A) binding protein, nuclear 1 SRSF3 splicing factor, arginine/serine-rich EIF1 aka SUI1 EIF1AD EIF1B EIF2A EIF2AK1...
    48 KB (4,612 words) - 23:41, 12 December 2023
  • Thumbnail for HIV
    virion such as reverse transcriptase, proteases, ribonuclease and integrase. A matrix composed of the viral protein p17 surrounds the capsid ensuring the...
    125 KB (14,349 words) - 12:00, 24 June 2024
  • Thumbnail for Rheumatic fever
    Guilherme L (2008). "Association of Mannose-Binding Lectin Gene Polymorphism but Not of Mannose-Binding Serine Protease 2 with Chronic Severe Aortic Regurgitation...
    57 KB (5,871 words) - 12:19, 4 June 2024
  • Thumbnail for C3-convertase
    response to binding to CRP or immunoglobulin, and in the lectin pathway it is driven by mannose binding lectin and its associated serine proteases (MASPs,...
    10 KB (1,319 words) - 09:52, 27 February 2024
  • Granzyme B (GrB) is one of the serine protease granzymes most commonly found in the granules of natural killer cells (NK cells) and cytotoxic T cells...
    16 KB (1,920 words) - 16:20, 9 June 2024
  • Thumbnail for Insulin
    Insulin (category Recombinant proteins)
    glucose and mannose) and vagal nerve stimulation to be exocytosed from the cell into the circulation. Insulin and its related proteins have been shown...
    121 KB (13,791 words) - 16:50, 29 June 2024
  • Thumbnail for Chromosome 5
    interacting protein (synphilin) SPEF2: Sperm flagellar protein 2 SPINK5: serine protease inhibitor Kazal-type 5 (LEKTI) SPINK6: serine protease inhibitor...
    32 KB (2,298 words) - 22:55, 28 March 2024
  • Thumbnail for Chromosome 6
    encoding protein Gametogenetin binding protein 1 (pseudogene) GMDS: GDP-mannose 4,6-dehydratase (6p25.3) GTPBP2: encoding protein Gtp binding protein 2 HCG4P11:...
    35 KB (2,420 words) - 20:47, 13 May 2024
  • Thumbnail for C3a (complement)
    including sugars. These bound receptors then complex with Mannose-Binding Lectin-Associated Serine Proteases (MASPs), which have proteolytic activity similar to...
    17 KB (2,036 words) - 05:36, 19 February 2024
  • TPP1, cerliponase alfa functions as a serine protease, cleaving N-terminal tripeptides from a broad range of protein substrates. The enzyme uses a catalytic...
    18 KB (1,789 words) - 09:52, 9 May 2024
  • Thumbnail for Murine respirovirus
    Paramyxoviruses use different host cell proteases to activate their F-proteins. Sendai virus uses activating proteases that are serine endopeptidases represented by...
    295 KB (31,886 words) - 17:12, 23 June 2024
  • Thumbnail for Complement component 1s
    Nonaka M, Fujita T (November 1998). "Two lineages of mannose-binding lectin-associated serine protease (MASP) in vertebrates". Journal of Immunology. 161...
    10 KB (1,195 words) - 05:11, 25 December 2023
  • Thumbnail for Acrosin
    Acrosin is a typical serine proteinase with trypsin-like specificity. The reaction proceeds according to the usual serine protease mechanism. First, His-57...
    20 KB (2,477 words) - 20:56, 30 December 2023
  • C Lee (1991-03-15). "Ligand-binding characteristics of rat serum-type mannose-binding protein (MBP-A). Homology of binding site architecture with mammalian...
    22 KB (2,721 words) - 01:46, 24 May 2024
  • Thumbnail for Morpheein
    Morpheein (category Proteins)
    Schwartz, Lawrence B. (1994). "[6] Tryptase: A mast cell serine protease". Proteolytic Enzymes: Serine and Cysteine Peptidases. Methods in Enzymology. Vol...
    81 KB (6,781 words) - 20:07, 2 April 2024
  • Thumbnail for Alveolar macrophage
    phosphorylate serine and threonine residues on many cellular proteins, especially transcription factor cAMP response element binding protein (CREB). cAMP/PKA/CREB...
    33 KB (3,862 words) - 16:23, 12 June 2024
  • Thumbnail for Chromosome 3
    encoding protein Transmembrane protein 44 TM4SF1: Transmembrane 4 L6 family member 1 TMPRSS7: encoding protein Transmembrane serine protease 7 TP63: Tumor...
    34 KB (1,978 words) - 16:11, 20 April 2024
  • Thumbnail for MBL deficiency
    or mannose-binding lectin deficiency is an illness that has an impact on immunity. Low levelsĀ of mannose-binding lectin, an immune system protein, are...
    10 KB (890 words) - 05:28, 29 January 2024