Marimastat was a proposed antineoplastic drug developed by British Biotech. It acted as a broad-spectrum matrix metalloproteinase inhibitor. Marimastat...

$2.5 billion, largely on the basis of its two main development drugs: marimastat (a novel matrix metalloprotease inhibitor for cancer treatment) and lexipafant...

called "hydroxamate-based MMP inhibitors“. An example can be seen in Marimastat, a first generation inhibitor, which has a similar backbone and sidechain...

suspected to be involved in (see above). However, most of these, such as marimastat (BB-2516), a broad-spectrum MMP inhibitor, and cipemastat (Ro 32-3555)...

with these compounds have to date produced equivocal results. Batimastat Marimastat Coussens, L. M. (2002). "Matrix Metalloproteinase Inhibitors and Cancer--Trials...

as anticancer drugs. Examples include: Batimastat Cipemastat Ilomastat Marimastat Prinomastat Tanomastat Metalloproteinase inhibitors are found in numerous...

administered orally (as opposed to the newer and chemically similar MMPI marimastat), and injection into the peritoneum caused peritonitis. It is well-known...

generally safe with minimal adverse side effects. Additionally, trials with marimastat did show a slight increase in survival of patients with gastric or pancreatic...

lymphoma – mammary – mammogram – mammography – Mammotome – mantle field – marimastat – mast cell – mastectomy – mastocytoma – matrix metalloproteinase – MDL...

inhibitors, DPP-4 inhibitors, and exogenous MMP inhibitors like batimastat and marimastat. Various enkephalinase inhibitors, such as ketalorphan, spinorphin, and...