• Thumbnail for Melanocyte
    Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer...
    20 KB (2,274 words) - 09:10, 28 July 2024
  • neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH)...
    10 KB (940 words) - 05:25, 31 October 2023
  • α-Melanocyte-stimulating hormone (α-MSH) is an endogenous peptide hormone and neuropeptide of the melanocortin family, with a tridecapeptide structure...
    8 KB (456 words) - 17:58, 15 September 2024
  • Thumbnail for Greying of hair
    of hair follicles produce melanocytes, the cells that produce and store pigment in hair and skin. The death of the melanocyte stem cells causes the onset...
    16 KB (1,856 words) - 13:37, 25 October 2024
  • Thumbnail for Β-Melanocyte-stimulating hormone
    β-Melanocyte-stimulating hormone (β-MSH) is an endogenous peptide hormone and neuropeptide. It is a melanocortin, specifically, one of the three types...
    3 KB (245 words) - 18:24, 15 September 2024
  • Thumbnail for Pituitary gland
    secreting prolactin). The intermediate lobe synthesizes and secretes melanocyte-stimulating hormone. The posterior pituitary (or neurohypophysis) is a...
    26 KB (2,800 words) - 20:39, 15 October 2024
  • release in hair follicles. This overproduction causes depletion of the melanocyte stem cells which are required to produce melanin, the pigment responsible...
    6 KB (728 words) - 03:48, 19 September 2024
  • γ-Melanocyte-stimulating hormone (γ-MSH) is an endogenous peptide hormone and neuropeptide. It is a melanocortin, specifically, one of the three types...
    4 KB (261 words) - 18:52, 15 September 2024
  • Thumbnail for Lentigo
    harmless (benign) hyperplasia of melanocytes which is linear in its spread. This means the hyperplasia of melanocytes is restricted to the cell layer directly...
    6 KB (604 words) - 16:35, 27 January 2024
  • Thumbnail for Vitiligo
    produced by skin cells called melanocytes. Variations in genes that are part of the immune system or part of melanocytes have both been associated with...
    42 KB (4,420 words) - 06:46, 27 October 2024
  • Thumbnail for Blue nevus
    nevus (also known as an "acquired dermal melanocytosis", and "dermal melanocyte hamartoma") is a cutaneous condition characterized by a diffusely gray-blue...
    6 KB (488 words) - 21:51, 12 September 2024
  • Thumbnail for Tortoiseshell cat
    are expressed in melanocytes that migrate to the skin surface later in development. In bi-colored tortoiseshell cats, the melanocytes arrive relatively...
    18 KB (2,044 words) - 00:51, 19 October 2024
  • Thumbnail for Melanocyte-inhibiting factor
    Melanocyte-inhibiting factor (also known as Pro-Leu-Gly-NH2, Melanostatin, MSH release–inhibiting hormone or MIF-1) is an endogenous peptide fragment derived...
    17 KB (1,892 words) - 23:03, 6 August 2024
  • Thumbnail for Piebaldism
    melanin-forming cells (melanocytes) in certain areas of the skin and hair. It is a rare autosomal dominant disorder of melanocyte development.: 867  Common...
    8 KB (836 words) - 17:07, 1 January 2024
  • Thumbnail for Acral lentiginous melanoma
    Melanoma is a group of serious skin cancers that arise from pigment cells (melanocytes); acral lentiginous melanoma is a kind of lentiginous skin melanoma....
    15 KB (1,429 words) - 21:58, 22 October 2024
  • Thumbnail for Grey
    specialized cell, the melanocyte, which is found in each hair follicle, from which the hair grows. As hair grows, the melanocyte injects melanin into the...
    30 KB (3,724 words) - 03:35, 23 October 2024
  • Thumbnail for Hyperpigmentation
    the body ages, melanocyte distribution becomes less diffuse and its regulation less controlled by the body. UV light stimulates melanocyte activity, and...
    16 KB (1,624 words) - 00:52, 19 September 2024
  • Thumbnail for Bicolor cat
    is co-dominant to normal coat colour as it prevents the migration of melanocytes into the developing hair follicles. The genetics of this pattern are...
    20 KB (2,317 words) - 19:47, 17 October 2024
  • Thumbnail for Skin whitening
    of which CREB is a transcription factor. Alpha-melanocyte stimulating hormone (α-MSH), beta-melanocyte stimulating hormone (β-MSH), and adrenocorticotropic...
    67 KB (7,644 words) - 13:03, 4 October 2024
  • undergoes cleavage to adrenocorticotropin (ACTH), β-lipotropin (β-LPH), and melanocyte-stimulating hormone (MSH). These cells are stimulated by corticotropin...
    16 KB (1,605 words) - 08:42, 3 July 2024
  • Thumbnail for Poliosis
    poliosis is marked by the lack of melanin or melanocytes in the hair bulbs, though epidermal melanocytes typically remain unaffected unless associated...
    11 KB (1,037 words) - 05:27, 27 September 2024
  • Thumbnail for Heterochromia iridum
    heterochromia. Piebaldism – similar to Waardenburg's syndrome, a rare disorder of melanocyte development characterized by a white forelock and multiple symmetrical...
    26 KB (2,873 words) - 21:06, 1 October 2024
  • Thumbnail for Keratinocyte
    containing the endogenous photoprotectant melanin, from epidermal melanocytes. Each melanocyte in the epidermis has several dendrites that stretch out to connect...
    25 KB (2,752 words) - 02:30, 23 October 2024
  • Thumbnail for Melanotan II
    Melanotan II is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis and increases sexual...
    17 KB (1,327 words) - 09:55, 25 July 2024
  • Thumbnail for Freckle
    an increased number of the melanin-producing cells, or melanocytes, but instead have melanocytes that overproduce melanin granules (melanosomes) changing...
    11 KB (1,293 words) - 16:49, 30 October 2024
  • Thumbnail for Pars intermedia
    fetus, this area produces melanocyte stimulating hormone (MSH) which causes the release of melanin produced in melanocytes that can give a darker skin...
    5 KB (573 words) - 22:48, 10 October 2024
  • Thumbnail for Leucism
    Albinism results in the reduction of melanin production only, though the melanocyte (or melanophore) is still present. Thus in species that have other pigment...
    10 KB (884 words) - 22:34, 16 September 2024
  • Thumbnail for Melanocytic nevus
    pigmented growth on the skin, formed mostly of a type of cell known as a melanocyte. The high concentration of the body's pigmenting agent, melanin, is responsible...
    28 KB (3,020 words) - 23:37, 17 October 2024
  • and activated by synthetic (i.e. afamelanotide) and endogenous agonist melanocyte-stimulating hormones. Several selective ligands for the melanocortin receptors...
    10 KB (1,143 words) - 18:46, 8 November 2023
  • Thumbnail for Lentigo maligna
    Lentigo maligna is where melanocyte cells have become malignant and grow continuously along the stratum basale of the skin, but have not invaded below...
    11 KB (1,307 words) - 06:51, 15 April 2024