Melatonin receptor 1C, also known as MTNR1C, is a protein that is encoded by the Mtnr1c gene. This receptor has been identified in fish, amphibia, and...
5 KB (488 words) - 07:56, 15 April 2024
Melatonin receptors are G protein-coupled receptors (GPCR) which bind melatonin. Three types of melatonin receptors have been cloned. The MT1 (or Mel1A...
23 KB (2,654 words) - 08:07, 10 March 2024
Melatonin receptor agonists are analogues of melatonin that bind to and activate the melatonin receptor. Agonists of the melatonin receptor have a number...
29 KB (2,894 words) - 16:33, 30 June 2024
Melatonin receptor 1B, also known as MTNR1B, is a protein that in humans is encoded by the MTNR1B gene. This gene encodes the MT2 protein, one of two high-affinity...
16 KB (1,640 words) - 08:07, 10 March 2024
Melatonin receptor type 1A is a protein that in humans is encoded by the MTNR1A gene. This gene encodes the MT1 protein, one of two high-affinity forms...
8 KB (1,006 words) - 09:39, 7 November 2023
with liver disease. Melatonin acts as an agonist of the melatonin MT1 and MT2 receptors, the biological targets of endogenous melatonin. It is thought to...
60 KB (5,849 words) - 05:55, 12 August 2024
Luzindole (category Melatonin receptor antagonists)
scientific research to study the role of melatonin in the body. Luzindole acts as a selective melatonin receptor antagonist, with approximately 11- to 25-fold...
5 KB (459 words) - 17:26, 5 August 2024
adrenergic receptor (α1A adrenoreceptor), also known as ADRA1A, formerly known also as the alpha-1C adrenergic receptor, is an alpha-1 adrenergic receptor, and...
11 KB (1,360 words) - 10:20, 23 June 2024
Ramelteon (category Melatonin receptor agonists)
levels. Ramelteon is an analogue of melatonin and is a selective agonist of the melatonin MT1 and MT2 receptors. The half-life and duration of ramelteon...
30 KB (2,894 words) - 17:28, 8 June 2024
N-Acetylserotonin (category Melatonin receptor agonists)
endogenous production of melatonin from serotonin. It also has biological activity in its own right, including acting as a melatonin receptor agonist, an agonist...
12 KB (1,142 words) - 23:43, 2 December 2023
protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G...
82 KB (9,384 words) - 18:56, 11 June 2024
MT3 may refer to: Melatonin receptor 1C Metallothionein-3 Montana Highway 3 This disambiguation page lists articles associated with the same title formed...
129 bytes (49 words) - 12:48, 29 December 2019
directly modulate the melatonin system in the body or brain. Examples include melatonin receptor agonists and melatonin receptor antagonists. Adenosinergic...
669 bytes (44 words) - 21:08, 29 November 2023
6-Hydroxymelatonin (category Melatonin receptor agonists)
endogenous, major active metabolite of melatonin. Similar to melatonin, 6-OHM is a full agonist of the MT1 and MT2 receptors. It is also an antioxidant and neuroprotective...
4 KB (214 words) - 02:59, 28 March 2024
Fabomotizole (category Melatonin receptor antagonists)
however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms...
6 KB (453 words) - 11:30, 4 June 2024
enzyme which catalyzes the final reaction in melatonin biosynthesis: converting Normelatonin to melatonin. This reaction is embedded in the more general...
20 KB (2,283 words) - 23:26, 28 November 2023
Agomelatine (category Melatonin receptor agonists)
antidepressants. It acts by blocking certain serotonin receptors and activating melatonin receptors. Agomelatine was approved for medical use in Europe in...
39 KB (3,632 words) - 15:35, 18 August 2024
2-Iodomelatonin (category Melatonin receptor agonists)
2-Iodomelatonin is a melatonin analog used as a radiolabelled ligand for the melatonin receptors, MT1, MT2, and MT3. It acts as a full agonist at both...
2 KB (102 words) - 21:37, 9 March 2024
Tasimelteon (category Melatonin receptor agonists)
for the melatonin receptors MT1 and MT2, similar to other members of the melatonin receptor agonist class of which ramelteon (2005), melatonin (2007),...
12 KB (1,110 words) - 13:24, 14 June 2024
of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled...
35 KB (3,892 words) - 05:20, 16 May 2024
by histamine Melatonin receptors – bound by melatonin Serotonin receptors – bound by serotonin (5-HT) Trace amine-associated receptors – bound by trace...
2 KB (163 words) - 11:14, 6 November 2023
Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the plasma membrane of cells. They act in cell...
21 KB (2,456 words) - 22:14, 21 November 2023
Olfactory receptors (ORs), also known as odorant receptors, are chemoreceptors expressed in the cell membranes of olfactory receptor neurons and are responsible...
36 KB (4,350 words) - 07:43, 3 June 2024
The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline)...
33 KB (2,982 words) - 11:42, 7 August 2024
GR-196,429 (category Melatonin receptor agonists)
GR-196,429 is a melatonin receptor agonist with some selectivity for the MT1 subtype. It was one of the first synthetic melatonin agonists developed and...
3 KB (194 words) - 04:36, 25 March 2024
receptor (β1 adrenoceptor), also known as ADRB1, can refer to either the protein-encoding gene (gene ADRB1) or one of the four adrenergic receptors....
31 KB (3,743 words) - 00:48, 23 July 2024
Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins...
40 KB (4,427 words) - 12:37, 12 January 2024
Muscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain...
31 KB (2,707 words) - 09:11, 16 June 2024
The glucagon-like peptide-1 receptor (GLP1R) is a G protein-coupled receptor (GPCR) found on beta cells of the pancreas and on neurons of the brain. It...
33 KB (4,071 words) - 15:36, 30 July 2024
TIK-301 (category Melatonin receptor agonists)
TIK-301 (LY-156735) is an agonist for the melatonin receptors MT1 and MT2 that is under development for the treatment of insomnia and other sleep disorders...
17 KB (1,686 words) - 05:28, 16 June 2024