• Thumbnail for Microtubule
    Microtubules are polymers of tubulin that form part of the cytoskeleton and provide structure and shape to eukaryotic cells. Microtubules can be as long...
    62 KB (7,838 words) - 13:27, 31 December 2024
  • The microtubule-organizing center (MTOC) is a structure found in eukaryotic cells from which microtubules emerge. MTOCs have two main functions: the organization...
    9 KB (1,113 words) - 17:22, 28 November 2024
  • destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with...
    12 KB (1,689 words) - 06:05, 30 December 2024
  • form of microtubule nucleation that generates fan-like branching arrays, in which new microtubules grow at an angle off of older microtubules. These branching...
    13 KB (1,601 words) - 17:13, 22 December 2024
  • Thumbnail for Spindle apparatus
    composed of hundreds of proteins. Microtubules comprise the most abundant components of the machinery. Attachment of microtubules to chromosomes is mediated...
    28 KB (3,300 words) - 12:32, 30 September 2024
  • Thumbnail for Cytoskeleton
    Additionally, the microtubules control the beating (movement) of the cilia and flagella. Also, the dynein arms attached to the microtubules function as the...
    45 KB (5,122 words) - 19:13, 4 December 2024
  • Thumbnail for Orchestrated objective reduction
    cytoskeleton, and particularly on microtubules. As neuroscience has progressed, the role of the cytoskeleton and microtubules has assumed greater importance...
    48 KB (5,233 words) - 11:44, 5 November 2024
  • Thumbnail for Prometaphase
    metaphase. The microtubules are composed of two types, kinetochore microtubules and non-kinetochore microtubules. Kinetochore microtubules begin searching...
    4 KB (337 words) - 15:31, 7 March 2024
  • Thumbnail for Tubulin
    polymerize into microtubules, a major component of the eukaryotic cytoskeleton. It was discovered and named by Hideo Mōri in 1968. Microtubules function in...
    32 KB (3,393 words) - 07:42, 25 November 2024
  • Thumbnail for Aster (cell biology)
    Astral microtubules are a subpopulation of microtubules, which only exist during and immediately before mitosis. They are defined as any microtubule originating...
    5 KB (631 words) - 23:27, 14 November 2024
  • Thumbnail for Mitosis
    Microtubules project from opposite ends of the cell, attach to the centromeres, and align the chromosomes centrally within the cell. The microtubules...
    71 KB (7,317 words) - 10:21, 19 December 2024
  • Thumbnail for Motor protein
    ends of microtubules located at the cell periphery, while kinesins with C-terminal motor domains move cargo towards the minus ends of microtubules located...
    13 KB (1,550 words) - 06:28, 1 January 2025
  • Thumbnail for Anaphase
    microtubules, and astral microtubules. The centromeres are split, and the sister chromatids are pulled toward the poles by kinetochore microtubules....
    6 KB (719 words) - 02:00, 2 May 2024
  • Thumbnail for Tau protein
    from the gene MAPT (microtubule-associated protein tau). They have roles primarily in maintaining the stability of microtubules in axons and are abundant...
    55 KB (6,284 words) - 05:15, 11 November 2024
  • Thumbnail for Protein filament
    the microtubules. These microtubules are structurally quantified into three main groups: singlets, doublets, and triplets. Singlets are microtubule structures...
    14 KB (1,806 words) - 22:50, 17 August 2024
  • Thumbnail for Axoneme
    consisted of nine doublet microtubules surrounding two central, singlet microtubules (i.e., the “central pair microtubule apparatus”), and hence the...
    10 KB (1,263 words) - 06:33, 20 November 2024
  • Thumbnail for Centrosome
    lack centrosomes and therefore use other structures to organize their microtubules. Although the centrosome has a key role in efficient mitosis in animal...
    24 KB (2,611 words) - 13:50, 13 September 2024
  • Thumbnail for Stuart Hameroff
    consciousness via action on neural microtubules. The two met in 1992, and Hameroff suggested that the microtubules were a good candidate site for a quantum...
    14 KB (1,556 words) - 11:30, 10 November 2024
  • extending microtubules in a non-autonomous manner. +TIPs' localization at the plus end of microtubules is a highly relevant aspect of microtubule regulation...
    8 KB (875 words) - 07:52, 27 May 2024
  • "Identification of katanin, an ATPase that severs and disassembles stable microtubules". Cell. 75 (3): 419–29. doi:10.1016/0092-8674(93)90377-3. PMID 8221885...
    2 KB (157 words) - 14:58, 26 August 2023
  • Thumbnail for Mitotic inhibitor
    prophase, the microtubules required for cell division begin to form and grow towards the newly formed chromosomes,forming a bundle of microtubules called the...
    59 KB (6,976 words) - 05:14, 15 December 2024
  • Thumbnail for CAMSAP2
    responsible for the maintenance of non-centrosomal microtubules. In epithelial cells, major microtubules are not anchored to the centrosome, which can be...
    22 KB (2,395 words) - 07:22, 18 August 2024
  • Thumbnail for Intracellular transport
    motors that haul them along microtubules and actin filaments. Since intracellular transport heavily relies on microtubules for movement, the components...
    12 KB (1,474 words) - 21:00, 3 October 2023
  • Thumbnail for Treadmilling
    of the cytoskeletons of many cells, especially in actin filaments and microtubules. It occurs when one end of a filament grows in length while the other...
    12 KB (1,476 words) - 21:34, 5 December 2024
  • Thumbnail for Kinesin
    proteins act within the spindle to slide microtubules apart, while the Kinesin 13 family act to depolymerize microtubules. Human kinesin superfamily members...
    36 KB (4,259 words) - 06:31, 1 January 2025
  • Thumbnail for Microtubule-associated protein 2
    experiments: tubulin in cell extracts can be made to polymerize to produce microtubules (MT) under the influence of heat and the addition of GTP, and the MT...
    11 KB (1,380 words) - 17:46, 6 July 2024
  • Thumbnail for Dynein
    metaphase of mitosis. Dynein pulls the microtubules and chromosomes to one end of the cell. When the end of the microtubules become close to the cell membrane...
    29 KB (3,313 words) - 16:08, 3 December 2023
  • believes that microtubules within neurons support quantum superpositions. The objective collapse of the quantum wavefunction of the microtubules is critical...
    16 KB (1,755 words) - 02:26, 3 October 2024
  • Thumbnail for Eukaryote
    present in submembranous cortical layers and bundles. Motor proteins of microtubules, dynein and kinesin, and myosin of actin filaments, provide dynamic character...
    62 KB (6,208 words) - 12:14, 24 December 2024
  • encoded by KATNA1, which functions to sever microtubules. This subunit requires ATP and the presence of microtubules for activation. The second 80 kDA subunit...
    16 KB (1,693 words) - 01:52, 1 December 2023