• A myc tag is a polypeptide protein tag derived from the c-myc gene product that can be added to a protein using recombinant DNA technology. It can be...
    2 KB (296 words) - 22:15, 4 April 2024
  • of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered...
    57 KB (6,717 words) - 23:11, 17 August 2024
  • epitope. The FLAG-tag can be used in conjunction with other affinity tags, for example a polyhistidine tag (His-tag), HA-tag or myc-tag. The first use of...
    7 KB (846 words) - 22:41, 10 August 2024
  • high immunoreactivity. Epitope tags include ALFA-tag, V5-tag, Myc-tag, HA-tag, Spot-tag, T7-tag and NE-tag. These tags are particularly useful for western...
    24 KB (2,673 words) - 17:55, 22 July 2024
  • characterization. Common epitopes used for this purpose are Myc-tag, HA-tag, FLAG-tag, GST-tag, 6xHis, V5-tag and OLLAS. Peptides can also be bound by proteins...
    22 KB (2,495 words) - 16:40, 19 August 2024
  • Thumbnail for Glutathione S-transferase
    amino acids (roughly 26 kDa) in size, which, compared to tags such as the Myc-tag or the FLAG-tag, is quite large. It can be fused to either the N-terminus...
    38 KB (4,286 words) - 01:59, 22 June 2024
  • virus promoter used to express FLS2 coding sequences fused to a triple c-myc tag. What happens to a FLS2 gene in Arabidopsis is known but this study looks...
    14 KB (1,844 words) - 12:40, 27 December 2023
  • Thumbnail for ChIP-on-chip
    protein. This can be done either by using a tagged protein with an antibody against the tag (ex. FLAG, HA, c-myc) or with an antibody to the native protein...
    25 KB (3,057 words) - 05:34, 12 December 2023
  • Thumbnail for Affimer
    target binding. Many different tags and fusion proteins, such as fluorophores, single-stranded DNA, His, and c-Myc tags can be conjugated to Affimers....
    25 KB (2,484 words) - 10:24, 8 March 2024
  • Thumbnail for Dyslexia-associated protein
    C-terminally myc-tagged KIAA0319 protein in transiently transfected 293T cells, showing plasma membrane localization. Detection with monoclonal anti-myc 9E10...
    7 KB (855 words) - 15:20, 5 January 2024
  • Thumbnail for L-Photo-methionine
    cholesterol levels. Cells (COS7) that had HA (hemagglutinin tagged PGRMC1) and Myc tagged Insig-1 were grown with and without photo-Met. In the presence...
    21 KB (2,542 words) - 09:55, 8 November 2023
  • researched how MYC expression induces cancer in mice and the effect of its inactivation in those tumors. She showed that removing MYC expression kills...
    10 KB (1,020 words) - 01:02, 3 December 2023
  • Thumbnail for Medulloblastoma
    Medulloblastoma (category Articles tagged with the inline citation overkill template from June 2020)
    medulloblastoma. Additional pathways disrupted in some medulloblastomas include MYC, Notch, BMP, and TGF-β signaling pathways.[excessive citations] The tumor...
    36 KB (3,455 words) - 22:51, 26 April 2024
  • Thumbnail for Kavita Devi (wrestler)
    Devi Cagematch profile". Cagematch. Retrieved 15 October 2017. "Kavita Devi MYC Biography". WWE. Retrieved 15 October 2017. "Kavita Devi Wrestlingdata profile"...
    8 KB (672 words) - 19:51, 17 July 2024
  • Thumbnail for Cellular differentiation
    Virally induced expression of four transcription factors Oct4, Sox2, c-Myc, and Klf4 (Yamanaka factors) is sufficient to create pluripotent (iPS) cells...
    50 KB (6,033 words) - 03:30, 25 July 2024
  • nuclear localization signal or sequence (NLS) is an amino acid sequence that 'tags' a protein for import into the cell nucleus by nuclear transport. Typically...
    15 KB (2,036 words) - 18:37, 22 June 2024
  • Thumbnail for RNA-Seq
    regulators including chromatin remodelers, transcription factors (e.g., MYC), acetyltransferase complexes, and nucleosome positioning are not congruent...
    103 KB (11,098 words) - 04:11, 29 July 2024
  • a gene (known as a viral oncogene) normally near the cellular myc (c-myc)gene. The c-myc gene is normally turned off in the cell; however when it is turned...
    8 KB (1,037 words) - 11:48, 10 August 2023
  • Thumbnail for Developmental Studies Hybridoma Bank
    Epitope Tags Skeletal Muscle Transcription Factors Nobel Prize and Alfred P. Sloan, Jr. Prize winner J. Michael Bishop deposited the anti c-MYC hybridoma...
    6 KB (702 words) - 03:25, 31 December 2023
  • Thumbnail for Oct-4
    induced pluripotent stem cells (iPSCs), together with Sox2, Klf4, and often c-Myc (OSKM) in mice, demonstrating its capacity to induce an embryonic stem-cell-like...
    33 KB (3,818 words) - 23:33, 17 August 2024
  • Thumbnail for DNA
    Zhang MQ, Ren B (July 2003). "A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells". Proceedings of the National Academy of Sciences...
    166 KB (17,865 words) - 08:43, 15 August 2024
  • Thumbnail for Jasmonate
    best-studied transcription factors acting in this pathway belong to the MYC family of transcription factors, which are characterized by a basic helix-loop-helix...
    23 KB (2,887 words) - 22:51, 13 June 2024
  • Thumbnail for G-quadruplex
    gene region, the c-myc pathway, plays an integral role in the regulation of a protein product, c-Myc. With this product, the c-Myc protein functions in...
    93 KB (11,903 words) - 13:50, 21 August 2024
  • Thumbnail for Antibody
    PMID 12884279. S2CID 32059768. Casali P, Zan H (November 2004). "Class switching and Myc translocation: how does DNA break?". Nature Immunology. 5 (11): 1101–3. doi:10...
    118 KB (13,287 words) - 12:29, 5 August 2024
  • Thumbnail for HUWE1
    2005). "The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation". Cell. 123 (3): 409–21. doi:10...
    8 KB (906 words) - 17:48, 15 January 2024
  • Thumbnail for Proteasome
    Proteasomes are protein complexes which degrade ubiquitin-tagged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that help...
    105 KB (12,670 words) - 08:02, 23 August 2024
  • ISBN 9781405384230. Retrieved 7 June 2017. Iaccino, James F.; Barker, Cory; Wiatrowski, Myc (29 September 2017). Arrow and Superhero Television: Essays on Themes and...
    326 KB (14,573 words) - 18:52, 17 August 2024
  • Thumbnail for Ornithine decarboxylase
    T cells after activation. As with ODC and cancer, MYC, also referred to as c-Myc for cellular Myc, is the master regulator of polyamine biosynthesis...
    19 KB (2,082 words) - 12:53, 9 January 2024
  • Thumbnail for Glioma
    Glioma (category Cleanup tagged articles with a reason field from January 2022)
    O, Kenner L, Kleihues P, Wiestler OD (1993). "Tumor induction by ras and myc oncogenes in fetal and neonatal brain: modulating effects of developmental...
    61 KB (6,663 words) - 21:44, 7 August 2024
  • well as gene-specific probes for cancer-related genes, such as HER-2, EGFR, MYC, and TOP2A. Despite the limited variety of available CISH probes, they are...
    27 KB (3,039 words) - 20:41, 3 December 2023