• Thumbnail for NF-kappa-B-activating protein
    NF-kappa-B-activating protein is a protein that in humans is encoded by the NKAP gene. GRCh38: Ensembl release 89: ENSG00000101882 – Ensembl, May 2017...
    4 KB (492 words) - 16:09, 9 June 2024
  • Thumbnail for NF-κB
    Nuclear factor kappa-light-chain-enhancer of activated B cells (NFB) is a family of transcription factor protein complexes that controls transcription...
    89 KB (9,773 words) - 11:16, 4 October 2024
  • Thumbnail for IKBKG
    NF-kappa-B essential modulator (NEMO) also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK-γ) is a protein that in humans is encoded...
    26 KB (3,277 words) - 15:04, 23 July 2024
  • Thumbnail for TMEM101
    to breast cancer. Known aliases of TMEM101 include Putative NF-Kappa-B-Activating Protein 130, FLJ23987, and MGC4251. TMEM101 is located on the minus...
    20 KB (1,391 words) - 00:44, 17 October 2024
  • The IκB kinase enzyme complex is part of the upstream NFB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates...
    14 KB (1,447 words) - 09:31, 22 December 2023
  • Thumbnail for NKAPD1
    NKAPD1 (category Human proteins)
    NKAPD1 (NF-kappa-B-activating protein domain containing 1) is a protein, which in humans, is encoded by the gene NKAPD1. This protein is also commonly...
    10 KB (707 words) - 07:39, 12 February 2024
  • Thumbnail for IκBα
    IκBα (redirect from I-kappa B protein)
    function to inhibit the NFB transcription factor. IκBα inhibits NFB by masking the nuclear localization signals (NLS) of NFB proteins and keeping them...
    13 KB (1,526 words) - 18:27, 5 February 2024
  • Thumbnail for B-cell activating factor
    B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B and CD257 among other names, is a protein that in humans...
    25 KB (3,095 words) - 14:05, 12 March 2024
  • Thumbnail for Transforming growth factor beta
    1996). "TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alpha". Immunity. 5 (1): 31–40...
    67 KB (8,184 words) - 20:48, 31 October 2024
  • Thumbnail for Protein phosphorylation
    PMID 24886973. Hou, Shihe (November 14, 2003). "Phosphorylation of serine 337 of NF-kappaB p50 is critical for DNA binding". The Journal of Biological Chemistry...
    67 KB (7,955 words) - 20:50, 29 July 2024
  • Thumbnail for RELA
    NF-kappa-B p65 subunit is a protein that in humans is encoded by the RELA gene. RELA, also known as p65, is a REL-associated protein involved in NF-κB...
    56 KB (6,507 words) - 07:54, 19 July 2024
  • Thumbnail for AKT1
    AKT1 (category Protein kinases)
    Schraven B, Baier G (Aug 2001). "Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation...
    24 KB (2,803 words) - 10:09, 29 October 2024
  • Thumbnail for TRAF3IP2
    with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase...
    10 KB (1,139 words) - 09:01, 29 December 2023
  • Thumbnail for NFKB1
    Nuclear factor NF-kappa-B p105 subunit is a protein that in humans is encoded by the NFKB1 gene. This gene encodes a 105 kD protein which can undergo cotranslational...
    20 KB (2,363 words) - 03:00, 19 December 2023
  • Thumbnail for Molluscum contagiosum virus
    inhibitor of NFB, allowing NFB to be activating. When MC160 binds heat shock protein 90, IKK is degraded and the inhibitor remains bound to NFB, thus making...
    21 KB (2,676 words) - 10:59, 6 January 2024
  • Thumbnail for Tumor necrosis factor
    wasting by activating the NFB pathway, which activates the ubiquitin–proteasome pathway to degrade protein, and by inhibiting the activation of satellite...
    49 KB (6,233 words) - 07:30, 6 November 2024
  • Thumbnail for Sirtuin 1
    deactivate the p53 protein, and may have a role in activating T helper 17 cells. Lamin A is a protein that had been identified as a direct activator of Sirtuin...
    26 KB (3,126 words) - 05:58, 11 June 2024
  • Thumbnail for BCL10
    BCL10 (category Proteins)
    (1999). "CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10". J. Biol. Chem....
    15 KB (1,813 words) - 14:39, 26 January 2024
  • Thumbnail for Mitochondrial antiviral-signaling protein
    characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3". Cell. 122 (5): 669–682. doi:10.1016/j.cell.2005...
    16 KB (1,931 words) - 19:24, 19 August 2024
  • Thumbnail for RANKL
    osteoblasts' surface-bound RANKL activating the osteoclasts' surface-bound receptor activator of nuclear factor kappa-B (RANK). Recent studies suggest that...
    28 KB (3,305 words) - 13:29, 8 November 2024
  • Thumbnail for AP-1 transcription factor
    2003). "Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein". Journal...
    41 KB (4,468 words) - 17:08, 21 September 2024
  • Thumbnail for TNFAIP3
    (TNF). The protein encoded by this gene is a zinc finger protein and a deubiquitinating enzyme, and has been shown to inhibit NF-kappa B activation as well...
    16 KB (1,971 words) - 14:55, 15 October 2024
  • Thumbnail for CD40 (protein)
    Kovalenko AV, Wallach D (February 1997). "MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1". Nature. 385 (6616): 540–544. doi:10...
    22 KB (2,808 words) - 16:03, 28 October 2024
  • Thumbnail for MYD88
    MYD88 (category Human proteins)
    interleukin-1beta -induced NF-kappa B activation by calcium/calmodulin-dependent protein kinase kinase occurs through Akt activation associated with interleukin-1...
    20 KB (2,250 words) - 15:55, 30 July 2024
  • Thumbnail for B-cell maturation antigen
    superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members,...
    18 KB (1,937 words) - 21:50, 5 January 2024
  • Thumbnail for NFKB2
    Nuclear factor NF-kappa-B p100 subunit is a protein that in humans is encoded by the NFKB2 gene. NFB has been detected in numerous cell types that express...
    10 KB (1,276 words) - 00:06, 3 December 2023
  • Thumbnail for Protein c-Fos
    Cheong J, Meltzer PS, Lee YC, Lee JW (June 2000). "Activating protein-1, nuclear factor-kappaB, and serum response factor as novel target molecules...
    26 KB (3,991 words) - 05:29, 10 July 2024
  • Thumbnail for Transcription factor
    region) 4.1.1 Family: Rel/ankyrin; NF-kappaB 4.1.2 Family: ankyrin only 4.1.3 Family: NFAT (Nuclear Factor of Activated T-cells) (NFATC1, NFATC2, NFATC3)...
    74 KB (8,192 words) - 19:50, 7 November 2024
  • Thumbnail for CEBPB
    CEBPB (redirect from NF-IL6)
    CCAAT/enhancer-binding protein beta is a protein that in humans is encoded by the CEBPB gene. The protein encoded by this intronless gene is a bZIP transcription...
    20 KB (2,336 words) - 16:02, 5 November 2024
  • Thumbnail for BCL3
    kappa B proteins. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression...
    23 KB (2,553 words) - 23:08, 3 August 2024