• Thumbnail for Neurotrophin
    Neurotrophins are a family of proteins that induce the survival, development, and function of neurons. They belong to a class of growth factors, secreted...
    28 KB (3,088 words) - 19:11, 28 November 2024
  • Thumbnail for Low-affinity nerve growth factor receptor
    The p75 neurotrophin receptor (p75NTR) was first identified in 1973 as the low-affinity nerve growth factor receptor (LNGFR) before discovery that p75NTR...
    37 KB (4,235 words) - 21:48, 19 November 2024
  • Thumbnail for Neurotrophin-4
    Neurotrophin-4 (NT-4), also known as neurotrophin-5 (NT-5), is a protein that in humans is encoded by the NTF4 gene. It is a neurotrophic factor that...
    11 KB (1,241 words) - 12:35, 9 January 2024
  • Thumbnail for Neurotrophin-3
    Neurotrophin-3 is a protein that in humans is encoded by the NTF3 gene. The protein encoded by this gene, NT-3, is a neurotrophic factor in the NGF (Nerve...
    14 KB (1,816 words) - 04:39, 31 October 2023
  • Neurotrophin mimetics are small molecules or peptide like molecules that can modulate the action of the neurotrophin receptor. One of the main causes of...
    34 KB (3,791 words) - 22:59, 7 December 2024
  • Thumbnail for Dehydroepiandrosterone
    the neurotrophin receptors from early on in the evolution of the nervous system. The findings that DHEA binds to and potently activates neurotrophin receptors...
    42 KB (3,937 words) - 11:44, 15 November 2024
  • Thumbnail for Brain-derived neurotrophic factor
    that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth...
    46 KB (5,344 words) - 15:43, 27 November 2024
  • Thumbnail for Tropomyosin receptor kinase C
    gene. TrkC is the high affinity catalytic receptor for the neurotrophin NT-3 (neurotrophin-3). As such, TrkC mediates the multiple effects of this neurotrophic...
    30 KB (3,901 words) - 17:05, 28 November 2024
  • axons. Most neurotrophic factors belong to one of three families: (1) neurotrophins, (2) glial cell-line derived neurotrophic factor family ligands (GFLs)...
    16 KB (1,784 words) - 04:08, 6 January 2024
  • Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to neurotrophins (neurotrophic factors)....
    5 KB (670 words) - 17:28, 23 January 2021
  • Brain-derived neurotrophic factor (BDNF) Nerve growth factor Neurotrophin-3 Neurotrophin-4 Ephrins Neuregulins Molecule Biomolecule Macromolecule Supermolecule...
    6 KB (596 words) - 17:05, 17 June 2022
  • Thumbnail for Tropomyosin receptor kinase B
    "neurotrophins", which are small protein growth factors that induce the survival and differentiation of distinct cell populations. The neurotrophins that...
    39 KB (4,391 words) - 05:30, 23 October 2024
  • Each type of neurotrophin has different binding affinity toward its corresponding Trk receptor. The activation of Trk receptors by neurotrophin binding may...
    27 KB (3,122 words) - 21:45, 8 July 2024
  • Thumbnail for LM11A-31
    Longo, Frank M.; El-Remessy, Azza B. (2019). "Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinal vascular permeability...
    8 KB (542 words) - 11:21, 14 November 2024
  • Thumbnail for Monoamine neurotransmitter
    neurotransmitters play an important role in the secretion and production of neurotrophin-3 by astrocytes, a chemical which maintains neuron integrity and provides...
    7 KB (1,409 words) - 21:17, 11 March 2024
  • Thumbnail for Dehydroepiandrosterone sulfate
    steroid is hormonally inert and is instead an important neurosteroid and neurotrophin. Similarly to other conjugated steroids, DHEA-S is devoid of hormonal...
    28 KB (2,570 words) - 16:18, 29 November 2023
  • Thumbnail for Liver
    K, Tanaka M, Watanabe N, Saito S, Nonaka H, Miyajima A (2008). "p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts...
    87 KB (10,329 words) - 05:37, 5 November 2024
  • Thumbnail for Nervous system
    molecules called neurotrophins which regulate the growth and survival of neurons. Zhu et al. identified DNT1, the first neurotrophin found in flies. DNT1...
    72 KB (9,249 words) - 21:36, 14 December 2024
  • Thumbnail for Nerve growth factor
    survival. Alternatively, programmed cell death occurs when TRAF6 and neurotrophin receptor interacting factor (NRIF) are both recruited to activate c-Jun...
    27 KB (3,107 words) - 17:30, 30 November 2024
  • Thumbnail for Amitriptyline
    Pleiotrophin Renalase Thrombopoietin (see here instead) Wnt signaling proteins Additional growth factor receptor modulators: Cerebrolysin (neurotrophin mixture)...
    93 KB (8,733 words) - 03:33, 16 December 2024
  • Thumbnail for Tropomyosin receptor kinase A
    receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself (autophosphorylation) and members of the...
    28 KB (3,328 words) - 15:54, 29 October 2024
  • experimental tests using animal subjects, neurotrophic factors, specifically neurotrophin-3, were shown to potentially reverse the neuropathy caused from the vitamin...
    49 KB (4,453 words) - 15:20, 26 August 2024
  • cultural phenomenon. Love is influenced by hormones (such as oxytocin), neurotrophins (such as NGF), and pheromones, and how people think and behave in love...
    86 KB (10,030 words) - 06:00, 22 December 2024
  • Thumbnail for Insulin
    Pleiotrophin Renalase Thrombopoietin (see here instead) Wnt signaling proteins Additional growth factor receptor modulators: Cerebrolysin (neurotrophin mixture)...
    121 KB (13,799 words) - 10:33, 13 November 2024
  • Thumbnail for Dexamethasone
    Pleiotrophin Renalase Thrombopoietin (see here instead) Wnt signaling proteins Additional growth factor receptor modulators: Cerebrolysin (neurotrophin mixture)...
    73 KB (6,489 words) - 08:56, 21 December 2024
  • Thumbnail for Adenosine
    Lee FS, Chao MV (March 2001). "Activation of Trk neurotrophin receptors in the absence of neurotrophins". Proceedings of the National Academy of Sciences...
    32 KB (3,341 words) - 09:46, 22 December 2024
  • Neuregulin 4 (NRG4) Neurotrophins Brain-derived neurotrophic factor (BDNF) Nerve growth factor (NGF) Neurotrophin-3 (NT-3) Neurotrophin-4 (NT-4) Placental...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • cone, a filamentous projection of the axon that actively searches for neurotrophins released by the myotube. The specific patterning of synapse development...
    26 KB (3,488 words) - 05:24, 13 March 2024
  • Francesco; Maione, Sabatino; de Novellis, Vito (1 December 2011). "Role of Neurotrophins in Neuropathic Pain". Current Neuropharmacology. 9 (4): 523–529. doi:10...
    59 KB (6,671 words) - 20:45, 13 November 2024
  • Thumbnail for Type 1 diabetes
    ROS that result from insulitis and beta cell death stimulate the p75 neurotrophin receptor (p75NTR), which acts to prune off axons. Axons are normally...
    118 KB (13,899 words) - 09:33, 13 December 2024